Lactams
Medchemexpress LLC 2-(2,6-dioxopiperidin-3-yl)-4,5-difluoroisoindoline-1,3-dione | 2222115-19-5 | >98.0% | 294.21 g·mol⁻¹ | C13H8F2N2O4 | 50 MG
Thalidomide-4,5-F is a fluorinated analogue of thalidomide that serves as a cereblon (CRBN) ligand for E3 ligase recruitment and targeted protein degradation research. It promotes ubiquitinylation of proteins and is suitable for derivatization at its fluorine positions, making it a useful building block in PROTAC and molecular glue chemistries.
- Promotes ubiquitinylation of proteins.
- Useful as a cereblon ligand for E3 ligase recruitment and PROTAC synthesis.
- Fluorine positions amenable to further derivatization.
- High purity (>98.0%).
- Chemical formula C13H8F2N2O4; molecular weight 294.21 g·mol⁻¹.
- Appearance: white to off-white solid; available in multiple sizes.
Medchemexpress LLC Thalidomide-propargyne-PEG3-COOH | 2797649-54-6 | MFCD34473293 | 98.0% | 472.45 g/mol | C23H24N2O9 | 5 MG
Thalidomide-propargyne-PEG3-COOH is a thalidomide-based E3 ligase ligand-linker conjugate with a propargyl (alkynyl) handle and a PEG3 linker terminating in a carboxylic acid. Designed as a building block for PROTAC assembly and related chemical biology work, it is compatible with click chemistry and standard amide-coupling reactions. CAS 2797649-54-6; formula C23H24N2O9; MW 472.45; typical purity ~98%.
- Contains a propargyl (alkynyl) handle for CuAAC click chemistry.
- Includes a PEG3 linker terminating in a carboxylic acid for conjugation.
- Acts as a cereblon (CRBN) E3 ligase ligand for PROTAC design.
- Suitable for amide coupling and linker attachment.
- Supplied as a solid with high purity for research use.
![eMolecules 2227205-60-7 | tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate | Pharmablock212.293 | C11H20N2O2 | 97.000 | CC(C)(C)OC(=O)NC1CC2CNC1C2 | 25mg | 588505928](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502458980.PNG-250.jpg)
eMolecules 2227205-60-7 | tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate | Pharmablock212.293 | C11H20N2O2 | 97.000 | CC(C)(C)OC(=O)NC1CC2CNC1C2 | 25mg | 588505928
tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate | Pharmablock | 2227205-60-7212.293 | C11H20N2O2 | 97.000 | CC(C)(C)OC(=O)NC1CC2CNC1C2 | 25mg | 588505928
Medchemexpress LLC Fc epsilon RIA/FCER1 50ug
Recombinant human Fc epsilon RI alpha (extracellular domain) supplied as 50 μg lyophilized material with an N-terminal His-SUMO tag, intended for binding and functional studies involving human IgE.
- Prepared as lyophilized powder for long-term storage and transport.
- Includes N-terminal His-SUMO tag to facilitate affinity purification.
- Expression system: E. coli for efficient production.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Approximate molecular weight ~37 kDa for molecular characterization.
- Demonstrated IgE binding in ELISA with reported ED50 of 5.864 μg/mL.
Cambridge Isotope Laboratories N-METHYLCAPROLACTAM (N-METHYL-D3, 98%), 5 G
N-METHYLCAPROLACTAM (N-METHYL-D3, 98%), 5 G
Medchemexpress LLC CD3 epsilon Rhesus 50ug | 50ug
CD3 epsilon Protein a vital component of the TCR-CD3 complex on T-lymphocytes is pivotal for adaptive immune responses CD3E is crucial for proper T-cell development and contributes to TCR-CD3 complex internalization and down-regulation[1] CD3 epsilon Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived CD3 epsilon protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC CD3 epsilon protein (rat, HEK293-expressed, Fc tag) | ≥95.0% | 100 UG
Recombinant rat CD3 epsilon protein expressed in HEK293 cells with a C-terminal Fc tag, purified to ≥95% and supplied for use in immunoassays, binding studies, and antibody characterization.
- Recombinant rat CD3 epsilon (Y24-D103).
- Expressed in HEK293 cells for mammalian post-translational modifications.
- C-terminal Fc tag for improved stability and detection.
- Purity ≥95.0% as determined by supplier analysis.
- Supplied in a 100 μg format suitable for assay development.
- Common applications include TCR binding assays and antibody validation.
Medchemexpress LLC 14-3-3 epsilon Antibody (YA2629) | 100 UL
The 14-3-3 epsilon antibody (YA2629) is a rabbit-derived, non-conjugated IgG monoclonal antibody designed to target the 14-3-3 epsilon protein. This protein acts as an adapter involved in the regulation of diverse cellular signaling pathways by binding to phosphoserine or phosphothreonine motifs, thereby modulating the activity of binding partners. The antibody shows reactivity with human, mouse, and rat samples and is supplied as a liquid formulation.
- Reactivity with human, mouse, and rat samples
- Suitable for WB, IHC-P, ICC/IF, and FC applications
- Formulated in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipping with blue ice
Medchemexpress LLC CD23/Fc epsilon RII 100ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
Medchemexpress LLC 14-3-3 epsilon protein, mouse (His) | ≥98.0% | 50 UG
Recombinant mouse 14-3-3 epsilon His-tag protein supplied as a lyophilized powder for research use. The protein is produced in Escherichia coli, carries an N-terminal 6xHis affinity tag, and has an approximate molecular weight of 31 kDa. Supplied with high purity and low endotoxin for biochemical assays and binding studies.
- Recombinant protein expressed in Escherichia coli.
- N-terminal 6xHis tag for affinity purification and detection.
- Lyophilized powder formulation for extended shelf life.
- Approximate molecular weight 31 kDa.
- Purity ≥98.0% by reducing SDS-PAGE.
- Endotoxin <1 EU/μg (LAL), suitable for in vitro assays.
- Formulated in Tris-HCl, NaCl; reconstitute at ≥100 μg/mL.
- Store lyophilized at -20°C; freeze aliquots at -80°C for long term.
Medchemexpress LLC CD23/Fc epsilon RII 10ug
CD23/Fc epsilon RII Protein a low-affinity receptor for IgE and CR2/CD21 regulates IgE production and B cell differentiation On B cells it initiates IgE-dependent antigen uptake and presentation to T cells On macrophages IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding CD23/Fc epsilon RII Protein Mouse (HEK293 His) is the recombinant mouse-derived CD23/Fc epsilon RII protein expressed by HEK293 with N-His labeled tag
TARGETMOL CHEMICALS INC EPSILON-MOMFLUOROTHRIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Epsilon-momfluorothrin (Momfluorothrin (Z1R3R)-) a type I synthetic pyrethroid insecticide exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably its administration in rats has been observed to induce the development of hepatocellular tumors. purity: 99%