Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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5,866 – 5,880 of 178,527 results

5,866

Medchemexpress LLC Dioleyldimethylammonium chloride | 7212-69-3 | 95.9% | 582.47 g·mol⁻¹ | C38H76ClN | 100 MG

Dioleyldimethylammonium chloride (DODAC) is a cationic quaternary ammonium lipid used in research for liposome formulation and as a component in transfection reagents. Supplied with documented purity and storage recommendations, it is intended for laboratory research use only.

Cationic lipid for liposome formulation and transfection applications.
Purity 95.9% by supplied analysis.
Chemical formula C38H76ClN; molecular weight 582.47 g·mol⁻¹.
Available in small-scale quantities suitable for research use.
Storage recommendations include sealed, dry storage at 4°C and low-temperature solvent storage.

Pricing & Availability

5,867

Medchemexpress LLC Phenol, 3,5-bis(1,1-dimethylethyl)- | 1138-52-9 | MFCD00008829 | 100.0% | 206.33 g/mol | C14H22O | 25 G

3,5-Di-tert-butylphenol is a substituted phenolic research reagent (CAS 1138-52-9) used in antifungal and anti-biofilm studies and as a chemical building block for analytical and synthetic applications. It is supplied as a high-purity solid and as ready-to-use DMSO solutions, and is provided with supporting documentation for research use.

High purity, 99.98% assay reported on the COA.
Available as solid and as 10 mM solutions in DMSO.
Provided with datasheet, certificate of analysis, and safety data sheet.
Offered in multiple package sizes, including 25 g and larger bulk quantities.
Molecular formula C14H22O; molecular weight 206.33 g/mol.

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5,868

Medchemexpress LLC Nadifloxacin | 124858-35-1 | 99.9% | 1 ML

Nadifloxacin is a broad-spectrum quinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, thereby interfering with DNA replication. It also suppresses the production of proinflammatory cytokines such as IL-1α, IL-6, and IL-8. This compound demonstrates antibacterial activity against various pathogens, including *Propionibacterium acnes* and *Staphylococcus aureus*, and also exhibits anti-inflammatory activity. It is utilized in the research of skin infections like acne vulgaris, folliculitis, and impetigo.

Inhibits bacterial DNA gyrase and topoisomerase IV
Suppresses proinflammatory cytokines (IL-1α, IL-6, IL-8)
Exhibits antibacterial activity against *Propionibacterium acnes* and *Staphylococcus aureus*
Shows anti-inflammatory activity
Used in research for skin infections
Potent activity against *Propionibacterium acnes* isolated from acne vulgaris

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5,869

Medchemexpress LLC IFN-alpha 13/IFNA13 100ug

IFN-alpha 13 (IFNA13) belongs to type I interferon family is produced by macrophages with antiviral activities[1] IFN-alpha 13/IFNA13 Protein Cynomolgus (HEK293 His) contains 166 a a (C25-E190) produced in HEK293 cells with a C-terminal His-tag

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5,870

Medchemexpress LLC Ceftriaxone | 73384-59-5 | 99.6% | 5 MG

Ceftriaxone is a broad-spectrum β-lactam third-generation cephalosporin antibiotic. It exhibits good antibacterial activity against various gram-negative and positive bacteria. It is a covalent inhibitor of GSK3β and an inhibitor of Aurora B. Ceftriaxone also possesses anti-inflammatory, antitumor, and antioxidant activities, making it useful in studies of bacterial infections and meningitis.

Broad-spectrum β-lactam third-generation cephalosporin antibiotic
Good antibacterial activity against gram-negative and positive bacteria
Covalent inhibitor of GSK3β
Inhibitor of Aurora B
Exhibits anti-inflammatory properties
Exhibits antitumor properties
Exhibits antioxidant properties
Useful in studies of bacterial infections
Useful in studies of meningitis

Pricing & Availability

5,871

Medchemexpress LLC Tropicamide | 1508-75-4 | 98.9% | 1 G

Tropicamide is a selective M4 muscarinic acetylcholine receptor antagonist. It is commonly used as an eye drop to induce short-term mydriasis (pupil dilation) and cycloplegia. This compound is valuable in the research of neurological diseases, such as epilepsy.

Can be used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Improves perseverative behavior, learning, and memory in Fmr1KO mice models
Reduces the occurrence of seizures
Decreases pilocarpine-induced tremulous jaw movements in rat models

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5,872

Medchemexpress LLC Busulfan | 55-98-1 | 99.9% | 1 ML

Busulfan is a potent alkylating antineoplastic agent that causes DNA damage by cross-linking DNAs and DNA and proteins. It also inhibits thioredoxin reductase and induces apoptosis, acting as both an immunosuppressive and myeloablative chemotherapeutic agent.

Causes DNA damage by cross-linking DNAs and DNA and proteins
Inhibits thioredoxin reductase
Induces apoptosis
Functions as an immunosuppressive agent
Functions as a myeloablative chemotherapeutic agent
Can be used to induce aplastic anemia models

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5,873

Medchemexpress LLC Cidofovir | 113852-37-2 | 99.95% | 279.19 | 50 MG

Cidofovir is an acyclic monophosphate nucleotide analogue and a potent inhibitor of cytomegalovirus (CMV). It exerts its antiviral activity by selectively inhibiting viral DNA polymerase. This compound induces apoptosis and is utilized in studies concerning AIDS cytomegalovirus retinitis, herpes, and various cancers. Additionally, it demonstrates anti-orthopoxvirus and anti-variola activities.

Acyclic monophosphate nucleotide analogue
Inhibits cytomegalovirus (CMV) replication
Selectively inhibits viral DNA polymerase
Induces apoptosis
Used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer
Exhibits anti-orthopoxvirus and anti-variola activities
High purity of 99.95%

Pricing & Availability

5,874

Medchemexpress LLC IFNAR1 Cynomolgus 50ug

Recombinant IFNAR1 protein derived from cynomolgus macaque and produced in HEK293 cells, supplied lyophilized with a C-terminal 6xHis tag. The protein is provided at >95% purity and is intended for research use in type I interferon receptor biology, receptor-ligand interaction assays, and signaling studies.

Expressed in HEK293 cells to support proper mammalian folding and post-translational modifications.
C-terminal 6xHis tag for straightforward detection and purification.
Greater than 95% purity by reducing SDS-PAGE for consistent experimental results.
Lyophilized formulation from PBS (pH 7.4) for convenient storage and handling.
Sequence range corresponds to XP_005548864 (A25-K437), enabling studies of native receptor domains.
Recommended storage at -20°C with aliquoting to maintain stability and activity.

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5,875

Apexbio Technology LLC Tariquidar(Synonyms: XR9576, Tariquidar fumarate, XR-9576, UNII-1W8830WSA2, P-glycoprotein inhibitor XR9576), 50mg, CAS: 206873-63-4.

Tariquidar (CAS 206873-63-4) is a small-molecule inhibitor targeting the efflux transporter P-glycoprotein (Pgp) Pgp a 170-kDa transmembrane protein functions primarily as an ATP-dependent drug efflux pump removing structurally diverse molecules from cells Tariquidar acts through noncompetitive inhibition of Pgp-associated basal ATPase activity thereby reducing drug efflux In vitro assays across several cell models demonstrate tariquidar-mediated Pgp inhibition with IC50 values ranging from 15 to 223 nM Due to its selectivity for Pgp tariquidar serves as a significant research tool in studies of drug resistance and transporter-mediated drug disposition

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5,876

Medchemexpress LLC Trazodone | 19794-93-5 | 99.8% | 50 MG

Trazodone (AF-1161 free base) is a triazolopyridine derivative and a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates anti-depressant and anti-insomnious activity. It also shows antagonistic properties against a1- and a2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects.

Binds to 5-HT1A receptor with a Ki of 23.6 nM.
Reduces neuroinflammatory markers by inhibiting NF-κB, p38 MAPK, and JNK pathways.
Exhibits neuroprotective effects.
Increases mRNA expression of BDNF and CREB.
Decreases IFN-γ release.
Decreases spontaneous firing rate of DR 5-HT neurons and blocks 5-HT reuptake.
Reduces spontaneous motor activity, hyperactivity, prostration, and clonic convulsions in animal models.
Inhibits nicotine and oxotremorine-induced tremor.

Pricing & Availability

5,877

Medchemexpress LLC Ospemifene | 128607-22-7 | 99.8% | 100 MG

Ospemifene (FC-1271a) is an orally active and non-estrogenic selective estrogen receptor modulator (SERM) with Ki values of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. It inhibits caspase-3 activity, neuronal degeneration, prevents bone loss, and increases vaginal weight and vaginal epithelial height. Ospemifene also exhibits anticancer activity against breast cancer.

Inhibits caspase-3 activity.
Inhibits neuronal degeneration.
Prevents bone loss.
Increases vaginal weight and vaginal epithelial height.
Exhibits anticancer activity against breast cancer.

Pricing & Availability

5,878

Medchemexpress LLC Captopril (Standard) | 62571-86-2 | 99.8% | 100 MG

Captopril (Standard) is the analytical standard of Captopril. This product is intended for research and analytical applications. Captopril (SQ 14225), an antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.

Intended for research and analytical applications.
Thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
Used for research of hypertension and congestive heart failure.
New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.
Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC, and MS.

Pricing & Availability

5,879

Medchemexpress LLC Ibutilide | 122647-31-8 | 99.0% | 5 MG

Ibutilide (U70226E free base) is an action potential-prolonging antiarrhythmic agent that acts as a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. It inhibits Cav1.2 current in CHO cells and prolongs cardiac repolarization in vivo.

Potent IKr blocker with an EC50 of 20 nM at +20 mV in atrial tumor myocytes.
Inhibits Cav1.2 current with an IC50 of 62.5 μM in CHO cells.
Blocks IKr in HERG+MDR1*1 and HERG alone, showing resistance in MDR1*7 expressing cells.
Store pure form at -20°C for 3 years or 4°C for 2 years.
Store in solvent at -80°C for 6 months or -20°C for 1 month.
Shipping at room temperature if less than 2 weeks.
Keep container sealed in a cool, well-ventilated area, away from direct sunlight and ignition sources.

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5,880

Cayman Chemical AG183 Inhibitors

An inhibitor of EGF receptor kinase (IC50 = 0.8 µM in A431 cells)

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Pyridines and derivatives

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Medchemexpress LLC Dioleyldimethylammonium chloride | 7212-69-3 | 95.9% | 582.47 g·mol⁻¹ | C38H76ClN | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phenol, 3,5-bis(1,1-dimethylethyl)- | 1138-52-9 | MFCD00008829 | 100.0% | 206.33 g/mol | C14H22O | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nadifloxacin | 124858-35-1 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC IFN-alpha 13/IFNA13 100ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ceftriaxone | 73384-59-5 | 99.6% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tropicamide | 1508-75-4 | 98.9% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Busulfan | 55-98-1 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cidofovir | 113852-37-2 | 99.95% | 279.19 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC IFNAR1 Cynomolgus 50ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Tariquidar(Synonyms: XR9576, Tariquidar fumarate, XR-9576, UNII-1W8830WSA2, P-glycoprotein inhibitor XR9576), 50mg, CAS: 206873-63-4. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trazodone | 19794-93-5 | 99.8% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ospemifene | 128607-22-7 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Captopril (Standard) | 62571-86-2 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ibutilide | 122647-31-8 | 99.0% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Cayman Chemical AG183 Inhibitors Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More