Pyridines and derivatives
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Filtered Search Results
Medchemexpress LLC Prolactin Human HE 100ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant human prolactin expressed in HEK293 cells and supplied as a lyophilized, C-terminal His-tagged protein for research applications. The product is glycosylated and highly pure, with low endotoxin and recommended storage and formulation guidelines to preserve activity.
- Mammalian-expressed glycosylated protein suitable for functional studies.
- High purity (>95%) by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) for sensitive assays.
- Lyophilized powder formulation for long-term storage.
- Recommended storage at -20°C or -80°C with carrier protein for extended stability.
- Includes amino acid sequence and defined residue range for reproducibility.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mefox | 79573-48-1 | 98.9% | 5MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Mefox | 79573-48-1 | 98.9% | 5MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bromosalicylchloranilide | 3679-64-9 | 99.2% | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Multifungin (Bromochlorosalicylanilide) is an antifungal agent used to treat oral candidiasis. It also prevents the formation and accumulation of Zearalenone and reduces the fungal population in stored-crushed corn. This product is for research use only and not sold to patients.
- Interacts with bacterial cell membranes, changing intracellular H+ and K+ ion levels.
- Destroys bacterial proton motive force (PMF), affecting respiratory chain function and ATP synthesis.
- Inhibits phosphatidic acid biosynthesis, exerting an antibacterial effect.
- Exhibits broad-spectrum antibacterial activity against various bacteria with MICs of 0.25-1 μg/mL.
- Shows anti-infectious activity in infected mouse models, reducing bacterial load.
- Exhibits anti-inflammatory activity in mouse peritonitis models, alleviating lung pathological changes.
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Medchemexpress LLC AN5777 | 491586-42-6 | 98.37% | 319.36 | 5 MG
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AN5777 is a GSPT1 degrader that significantly reduces GSPT1 through the ubiquitin-proteasome system. It induces G1 block and Apoptosis, and also exhibits antitumor activity. It is intended for research use only and not for sale to patients.
- GSPT1 degrader
- Significantly reduces GSPT1 through the ubiquitin-proteasome system
- Induces G1 block and apoptosis
- Has antitumor activity
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Selleck Chemical LLC Apitolisib (GDC-0980) S2696-1g
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Apitolisib (GDC-0980 RG7422 GNE 390) is a potent class I PI3K inhibitor for PI3K / / / with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays respectively Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay and highly selective versus other PIKK family kinases Apitolisib activates autophagy and apoptosis simultaneously in pancreatic cancer cells Phase 2
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Medchemexpress LLC Butyrylcholinesteras 1mg
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Butyrylcholinesterase (BCHE) Protein an esterase with broad substrate specificity crucially inactivates acetylcholine maintaining neurotransmitter homeostasis Beyond acetylcholine metabolism BCHE degrades neurotoxic organophosphates highlighting its detoxification role The enzyme s versatility underscores its critical function in safeguarding against harmful effects of neurotoxic compounds Butyrylcholinesterase/BCHE Protein Mouse (HEK293 His) is the recombinant mouse-derived Butyrylcholinesterase/BCHE protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC FCRL2 Human HEK293 50ug | 50ug
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The FCRL2 protein regulates normal and neoplastic B cell development and has been shown to be involved in complex processes that control B cell maturation Its tyrosine-phosphorylated isoform 2 interacts with PTPN6 suggesting the existence of a signaling pathway and emphasizing the role of this protein in cellular regulation FCRL2 Protein Human (HEK293 His) is the recombinant human-derived FCRL2 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC Mequitazine | 29216-28-2 | 100.0% | 1 ML
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Mequitazine is a potent, and long-acting histamine H1 antagonist. It is a potent H1-receptors selective antihistaminic drug widely studied and used for allergic disorders such as hay fever and urticaria.
- Potent, and long-acting histamine H1 antagonist.
- Potent H1-receptors selective antihistaminic drug.
- Widely studied and used for allergic disorders such as hay fever and urticaria.
- Demonstrates significant bactericidal effects against all the tested clinical isolates including Ps. aeruginosa.
- Its effect against the Gram-positive isolates is more pronounced.
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Medchemexpress LLC Carbamic acid, N,N-dimethyl-, 3-[[[4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinyl]carbonyl]amino]phenyl ester | 1192189-69-7 | 99.5% | 10 MM 1 ML
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LX7101 is a potent inhibitor of LIM-kinase, ROCK, and PKA. It exhibits significant selectivity for LIMK2, with IC50 values of 4.3 nM for LIMK2 and 32 nM for LIMK1 at 2 μM ATP. This compound shows potential for research in ocular hypertension and associated glaucoma.
- Potent LIM-kinase, ROCK, and PKA inhibitor
- Shows significant selectivity for LIMK2
- Has potential for ocular hypertension research
- Has potential for associated glaucoma research
- Reduces intraocular pressure in ocular normotensive rabbits
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Medchemexpress LLC Ad80 | 1384071-99-1 | 99.9% | 473.43 g·mol⁻¹ | C22H19F4N7O | 1 ML
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AD80 is a multikinase inhibitor that potently inhibits RET, RAF, SRC, and S6K while exhibiting greatly reduced mTOR activity. It is used in research to probe kinase-driven signaling and to evaluate anti-proliferative effects in cancer cell models. The compound is supplied as a 10 mM solution in DMSO (1 mL) and is intended for in vitro research use.
- Potent inhibition of RET, RAF, SRC, and S6K.
- Reduced activity against mTOR compared with other multikinase inhibitors.
- Suitable for in vitro kinase assays and cell-based signaling studies.
- High purity suitable for biochemical and cellular experiments (99.9%).
- Supplied as a ready-to-use 10 mM solution in DMSO, 1 mL.
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Medchemexpress LLC 5-benzofuranol, 2-[2-fluoro-6-(methylamino)-3-pyridinyl]- | 1054629-49-0 | 99.0% | 258.25 | 50 MG
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AZD4694 is a chemical compound primarily intended for laboratory research applications. It is supplied as a white to off-white solid with a molecular weight of 258.25. Analytical testing confirms a high purity of 98.96% by LCMS, ensuring reliability for experimental use. Optimal storage conditions are critical to maintain its stability, with specific temperature guidelines provided for both powder form and solutions.
- Provided as a white to off-white solid
- Suitable for laboratory research applications
- High purity of 98.96% verified by LCMS
- Stable under recommended storage conditions
- Specific storage guidelines for powder and in-solvent forms
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Ethos Biosciences Eosinophil Stain, 16oz, Ethos
Eosinophil Stain is a staining solution designed for hematology and cytology applications. Commonly used for the identification and differentiation of eosinophils in peripheral blood smears and related specimens, it provides clear cytoplasmic staining for reliable microscopic evaluation. The formulation delivers consistent color intensity to support accurate cell morphology assessment and differential counts. Ideal for routine diagnostic workflows, Eosinophil Stain is suitable for clinical, research, and educational laboratories.
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Medchemexpress LLC DBCO Ir catalyst | 2695594-15-9 | 93.1% | 1367.23 | 5 MG
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DBCO Ir catalyst is an iridium catalyst labeled with DBCO. It can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems. It acts as a catalyst in bioorthogonal reactions (e.g., copper-free click chemistry), facilitating the cycloaddition between DBCO and azide groups for specific labeling.
- Iridium catalyst labeled with DBCO
- Used for in situ labeling and imaging of biomolecules
- Suitable for constructing targeted drug delivery systems
- Acts as a catalyst in bioorthogonal reactions
- Facilitates cycloaddition between DBCO and azide groups
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Apexbio Technology LLC Clomipramine 303-49-1 25mg
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Clomipramine (CAS 303-49-1) is a tricyclic antidepressant that functions primarily as a potent inhibitor of serotonin (5-HT) reuptake with an IC50 value of 1 5 nM By blocking the reabsorption of serotonin at the synaptic cleft clomipramine increases synaptic serotonin levels which is associated with its antidepressant and anti-obsessive effects This compound is widely utilized in preclinical and clinical research to investigate the pathophysiology and potential treatments of depressive disorders and obsessive-compulsive disorder (OCD)
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Medchemexpress LLC Dolcanatide | 1092457-65-2 | 99.2% | 1681.89 | 1 MG
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Dolcanatide is an orally active agonist of guanylate cyclase-C (GC-C). It exhibits laxative, anti-nociceptive, and anti-inflammatory activities, making it suitable for research related to inflammatory bowel disease.
- Activates GC-C receptors to stimulate cGMP synthesis in T84 cells.
- Suppresses lipopolysaccharide-induced paracellular permeability in Caco-2 and T84 cells.
- Alleviates TNBS-induced rectal allodynia in rats.
- Alleviates stress-induced colorectal hypersensitivity (CRD) in rats.
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