Pyridines and derivatives
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (2)
- (7)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (17)
- (2)
- (1)
- (6)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (48)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
- (6)
- (1)
- (7)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (6)
- (4)
- (15)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (10)
- (1)
- (17)
- (9)
- (1)
- (1)
- (2)
- (4)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (11)
- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (23)
- (1)
- (16)
- (2)
- (2)
- (1)
- (1)
- (2)
- (6)
- (3)
- (1)
- (1)
- (7)
- (11)
- (3)
- (2)
- (1)
- (1)
- (2)
- (4)
- (5)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (34)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (17)
- (1)
- (13)
- (2)
- (3)
- (1)
- (5)
- (18)
- (1)
- (13)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (18)
- (11)
- (18)
- (1)
- (1)
- (3)
- (1)
- (17)
- (8)
- (6)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (4)
- (1)
- (3)
- (2)
- (7)
- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
- (8)
- (5)
- (6)
- (24)
- (2)
- (1)
- (2)
- (6)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (9)
- (12)
- (1)
- (12)
- (26)
- (8)
- (1)
- (1)
- (1)
- (7)
- (9)
- (1)
- (1)
- (1)
- (3)
- (1)
- (15)
- (5)
- (2)
- (2)
- (3)
- (4)
- (2)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (8)
- (6)
- (1)
- (2)
- (2)
- (7)
- (1)
- (1)
- (11)
- (8)
- (1)
- (3)
- (4)
- (1)
- (2)
- (6)
- (6)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (1)
- (5)
- (27)
- (2)
- (15)
- (4)
- (3)
- (9)
- (4)
- (4)
- (18)
- (8)
- (2)
- (4)
- (7)
- (1)
- (32)
- (2)
- (75)
- (1)
- (4)
- (53)
- (1)
- (3)
- (1)
- (10)
- (6)
- (33)
- (6)
- (1)
- (1)
- (106)
- (1)
- (9)
- (544)
- (5)
- (462)
- (42)
- (22)
- (130)
- (9)
- (1)
- (117)
- (1)
- (2)
- (3)
- (1)
- (1)
- (27)
- (32)
- (15)
- (4)
- (13)
- (12)
- (1)
- (2)
- (2)
- (13)
- (1)
- (2)
- (2)
- (1)
- (2)
- (20)
- (1)
- (1)
- (1)
- (1)
- (27)
- (6)
- (1)
- (1)
- (4)
- (5)
- (4)
- (5)
- (3)
- (1)
- (3)
- (1)
- (47)
- (1)
- (11)
- (364)
- (5)
- (3)
- (133)
- (1,015)
- (4)
- (2)
- (1)
- (3)
- (12)
- (904)
- (7)
- (35)
- (7)
- (2)
- (1)
- (418)
- (26)
- (4)
- (10)
- (1)
- (1)
- (4)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (4)
- (1)
- (3)
- (19)
- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (9)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (1)
- (1)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (5)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (3)
- (13)
- (1)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (5)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (3)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (4)
- (3)
- (6)
- (3)
- (1)
- (9)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (2)
- (6)
- (2)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (2)
- (3)
- (9)
- (4)
- (1)
- (4)
- (4)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (2)
- (5)
- (3)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (5)
- (1)
- (3)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (3)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (3)
- (3)
- (2)
- (1)
- (4)
- (1)
- (1)
- (4)
- (4)
- (1)
- (4)
- (3)
- (6)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (6)
- (3)
- (1)
- (5)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (4)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (5)
- (3)
- (5)
- (2)
- (4)
- (4)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (7)
- (1)
- (3)
- (3)
- (4)
- (3)
- (3)
- (5)
- (6)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (3)
- (3)
- (3)
- (4)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC Spermine(N3BBB) | 1190203-80-5 | C25H48N6O6 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies.
- Contains an azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC 2(1H)-Pyrimidinone, 4-[2-(3-bromophenyl)ethenyl]-6-(trifluoromethyl)- | 357158-20-4 | C13H8BrF3N2O | 10 MM / 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
BVFP binds to the PGRN588-593 peptide with a Kd of 20 μM. It can disrupt PGRN-SORT1 binding and inhibits SORT1-mediated rPGRN endocytosis.
- Binds to the PGRN588-593 peptide with a Kd of 20 μM.
- Disrupts PGRN-SORT1 binding.
- Inhibits SORT1-mediated rPGRN endocytosis.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC URAT1 inhibitor 3 | 2850331-30-3 | C14H8Cl2N2O2 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM. It demonstrates urate-lowering efficacy and is suitable for research on gout and hyperuricemia.
- Potent, orally active, and selective URAT1 inhibitor
- Has an IC50 value of 0.8 nM for URAT1
- Demonstrates urate-lowering efficacy
- Shows low toxicity at high concentrations in HepG2 and HK2 cells
- Does not cause hepatic or renal toxicities in mice at tested dosages
- Useful in research for gout and hyperuricemia
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC UC-764864 | 278806-03-4 | C19H18N2OS | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
UC-764864 is a UBE2N inhibitor that impedes UBE2N enzymatic activity. It exhibits cytotoxic effects and hinders UBE2N-dependent signaling in leukemic cells. Furthermore, UC-764864 blocks the ubiquitination of innate immune- and inflammatory-related substrates within human Acute Myeloid Leukemia (AML) cell lines.
- Inhibits UBE2N enzymatic activity
- Demonstrates cytotoxic effects in leukemic cells
- Inhibits UBE2N-dependent signaling in leukemic cells
- Blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC UNC7467 | 2922283-43-8 | C20H13NO3 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
UNC7467 is a potent IP6K inhibitor designed for use in obesity research. It effectively reduces levels of inositol pyrophosphates and has demonstrated the ability to ameliorate diet-induced obesity, insulin resistance, and hepatic steatosis in mouse models.
- Potent IP6K inhibitor
- Reduces levels of inositol pyrophosphates
- Useful for obesity research
- Ameliorates diet-induced obesity
- Improves insulin resistance
- Reduces hepatic steatosis in diet-induced obesity mice
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC EGFR-IN-69 | 2433837-65-9 | C31H37Cl2N7O3S | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor used in non-small-cell-lung-cancer (NSCLC) research. It demonstrates strong inhibitory activity against multiple EGFR mutations, including EGFRL858R/T790M/C797S (IC50 4.3 nM), EGFRL858R/T790M (IC50 6.6 nM), and EGFR19del/T790M/C797S (IC50 25.6 nM). The compound also shows antiproliferative and cytotoxic effects on BaF3 cell lines.
- Potent EGFR inhibitor
- Inhibits EGFR L858R/T790M/C797S, L858R/T790M, and del19/T790M/C797S mutations
- Used in NSCLC research
- Antiproliferative and cytotoxic activity against BaF3 cell lines
- Light yellow to yellow solid
- 99.58% purity
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Spermine(N3BBB) | 1190203-80-5 | C25H48N6O6 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Spermine(N3BBB) is a click chemistry reagent containing an azide group. It is utilized for various biochemical studies, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- Click chemistry reagent
- Contains an azide group
- Suitable for various biochemical studies
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC)
- Can be used as an ADC linker
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC XR8-89 | 2817811-16-6 | C29H36N4O2S | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
XR8-89 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 0.1 μM. It induces conformational changes in SARS-CoV-2 papain-like protease, inhibiting SARS-CoV-2 replication and can be used for SARS-CoV-2 research.
- Potent papain-like protease (PLpro) inhibitor
- Induces conformational changes in SARS-CoV-2 papain-like protease
- Inhibits SARS-CoV-2 replication
- Suitable for SARS-CoV-2 research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC MI-1851 | 2417283-44-2 | C34H53N15O6 | 100 UG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
MI-1851 is a potent furin inhibitor that prevents the proteolytic processing of the S protein of SARS-CoV-2 by endogenous flavoprotease in HEK293 cells and exhibits antiviral activity. It also inhibits the spread and proliferation of SARS-CoV-2 in Calu-3 cells and replication of DENV-2 and WNV in huh-7 cells.
- Prevents proteolytic processing of S protein of SARS-CoV-2.
- Exhibits antiviral activity.
- Strongly inhibits the spread of SARS-CoV-2 in Calu-3 cells.
- Inhibits DENV-2 and WNV replication.
- Does not affect PHH cell viability.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Edelinontrine | 1082744-20-4 | C20H25N7O2 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Edelinontrine (PF-04447943) is a potent and highly selective inhibitor of human recombinant PDE9A. It exhibits an IC50 of 12 nM for PDE9A, showing over 78-fold selectivity compared to other PDE family members.
- Potent inhibitor of human recombinant PDE9A.
- Demonstrates high selectivity over other PDE enzymes.
- Inhibits ANP stimulated cGMP in HEK whole cells expressing rhesus PDE9A2.
- Increases blood, brain, and cerebrospinal fluid concentrations in rats.
- Increases CSF cGMP levels in mice.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC CRT0063465 | C17H16BrN3O2 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
CRT0063465 is a ligand of Human PGK1 and Stress Sensor DJ1, with a Kd of 24 μM of PGK1. It modulates the shelterin complex composition and telomere length.
- Purity: 99.64%
- Molecular weight: 374.23
- Appearance: Solid
- Color: Off-white to light yellow
- Target: Phosphatase
- Pathway: Metabolic Enzyme/Protease
- Solubility (in vitro): DMSO: 20 mg/mL (53.44 mM)
- Storage (solid): 4°C, protect from light
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month (protect from light)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Apexbio Technology LLC LED209 245342-14-7 5mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
LED209 (CAS 245342-14-7) is a small-molecule inhibitor targeting the bacterial histidine sensor kinase QseC It is designed to selectively inhibit QseC thereby disrupting the phosphorylation-mediated signaling essential for the regulation of virulence gene expression in bacteria LED209 exerts its biological activity primarily through inhibition of the interaction between signaling molecules and QseC In cell-based studies LED209 demonstrates inhibitory activity with an IC50 value of less than 10 M Notably it suppresses the expression and secretion of bacterial virulence factors such as EspA and EspB and inhibits formation of attaching and effacing lesions in cultured epithelial cells infected by pathogenic Escherichia coli (EHEC) Based on these pharmacological properties LED209 holds research potential in the study of bacterial pathogenesis and the development of therapeutic alternatives to traditional antibiotics
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Plasma kallikrein-IN-4 | 1357954-34-7 | C22H23N7O | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Plasma kallikrein-IN-4 (Example 153) is a plasma kallikrein inhibitor with an IC50 of 0.016 μM against human plasma kallikrein.
- High purity
- Potent inhibitor
- Documented support: Data Sheet, COA, SDS, and Handling Instructions are available
- Detailed solubility information for in vitro use
- Recommended storage conditions
- Intended for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 101066-61-9 | 2-Chloroisonicotinaldehyde | Apollo Scientific | MFCD06651557 | 141.550 | C6H4ClNO | 97.000 | Clc1cc(C=O)ccn1 | 5g | 600855559
2-Chloroisonicotinaldehyde | Apollo Scientific | 101066-61-9 | MFCD06651557 | 141.550 | C6H4ClNO | 97.000 | Clc1cc(C=O)ccn1 | 5g | 600855559
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 10438-96-7 | Methylsulfamoyl Chloride | Accela ChemBio (ASD) | MFCD00126938 | 129.560 | CH4ClNO2S | 95.000 | CNS(Cl)(=O)=O | 5g | 507751815
Methylsulfamoyl Chloride | Accela ChemBio (ASD) | 10438-96-7 | MFCD00126938 | 129.560 | CH4ClNO2S | 95.000 | CNS(Cl)(=O)=O | 5g | 507751815
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More