Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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3,721 – 3,735 of 6,662 results

3,721

Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | MFCD00868190 | 99.9% | 337.24 g·mol⁻¹ | C17H18Cl2N2O | 10 MG

Etifoxine hydrochloride is a non-benzodiazepine GABAergic compound used in research to modulate GABAA receptor activity. It is supplied as the hydrochloride salt for improved handling and solubility, and is commonly used in preclinical studies of anxiolytic and anticonvulsant effects.

Acts as a positive allosteric modulator of GABAA receptors
Hydrochloride salt form for enhanced solubility
High purity suitable for research applications
Available in small research pack sizes for preclinical work
Used in studies of anxiolytic and anticonvulsant pharmacology

Pricing & Availability

3,722

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG

Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine-derived, potent and selective vasopressin V2 receptor antagonist (reported IC50 ≈14 nM) used as a research chemical for studies of vasopressin signaling and conditions such as hyponatremia and SIADH. It is supplied as a white to off-white solid and is commonly available in small milligram quantities or as a DMSO solution for in vitro and pharmacology experiments. Molecular formula C27H30ClN3O2; molecular weight 464.0 g/mol; CAS 138470-70-9.

High purity suitable for research (≈99.9%)
Potent V2 receptor antagonist activity for pharmacology studies
Available in solid and DMSO solution formats
Compact packaging for small-scale experiments
Standard identifiers provided for traceability

Pricing & Availability

3,723

Medchemexpress LLC LY3020371 hydrochloride | 1377615-44-5 | 99.2% | 395.81 | 5 MG

LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM. It exerts an antidepressant-like signature in vivo.

Potent, selective mGlu2/3 receptor antagonist.
Ki values of 5.3 nM for mGluR2 and 2.5 nM for mGluR3.
Blocks cAMP formation with an IC50 of 16.2 nM.
Exerts an antidepressant-like signature in vivo.
Blocks agonist-suppressed Ca2+ oscillations (IC50=34 nM) and in hippocampal slices (IC50=46 nM).
Intravenous injection leads to effective mGlu2/3 receptor blockade in rat cerebrospinal fluid.
Promotes wakefulness, reducing NREM sleep in Wistar rats.
Available in various sizes and forms.
High purity (99.18%).
Detailed documentation provided.
Solubility and dissolution protocols available.

Pricing & Availability

3,724

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.

Potent SUV39H2 inhibitor
Inhibits tumor growth in mouse xenograft models
Regulates production of γ-H2AX in cancer cells
Shows significant inhibition of tumor growth without detectable toxicity
Inhibits A549 cell growth with an IC50 of 0.67 μM
Exhibits growth suppressive effects in human cancer cell line derived xenograft models

Pricing & Availability

3,725

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG

SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG

Pricing & Availability

3,726

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme, with IC50 values of 33 μM for TET1 and 73 μM for TET2. It is valuable in the field of epigenetics and serves as a foundation for developing new therapeutics targeting DNA methylation and gene transcription.

Potent and selective cytosine-based inhibitor of TET enzyme.
Useful in epigenetics research.
Serves as a starting point for new therapeutics targeting DNA methylation and gene transcription.
Inhibitory activity is directly related to Cu(II) content; the Bobcat339-copper mixture shows significantly higher TET inhibition than either alone.
Significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells at 10 μM for 24 hours.

Pricing & Availability

3,727

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML

Azasetron hydrochloride (Y-25130 hydrochloride) is a benzamide derivative that functions as a potent and selective 5-HT3 receptor antagonist. It is currently under study for its application in treating chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist.
Used to study chemotherapy-induced nausea and vomiting (CINV).
Can effectively penetrate the skin and enter systemic circulation.

Pricing & Availability

3,728

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG

Nifenalol hydrochloride is a β-adrenergic receptor antagonist used in cardiac electrophysiology and pharmacology research. The compound is reported to induce early afterdepolarization (EAD) and is used to study arrhythmia and blood pressure-related effects.

Beta-adrenergic receptor antagonist activity
Induces early afterdepolarization useful for arrhythmia studies
Hydrochloride salt form for improved solubility
Molecular formula C11H17ClN2O3
Molecular weight 260.72
Available in small research pack sizes (e.g., 5 mg)
Intended for in vitro and in vivo research applications

Pricing & Availability

3,729

Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 10 MG

GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor and can be used for cancer study.

It is a cysteine cathepsin inhibitor.
It can be used for cancer study.
It is for research use only.
It has a purity of 99.26%.
Its appearance is a white to off-white solid.
It should be shipped at room temperature in continental US and may vary elsewhere.
Storage conditions are -20°C, sealed storage, away from moisture and light.
In solvent, it should be stored at -80°C for 6 months or -20°C for 1 month (sealed storage, away from moisture and light).
It is soluble in DMSO at 125 mg/mL.

Pricing & Availability

3,730

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML

Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. It prevents the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G by exerting a proximal effect in the complement cascade reaction. It can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G).

Effective and orally-active highly selective factor B inhibitor
IC50 value of 10 nM and KD of 7.9 nM
Prevents destruction (hemolysis) of red blood cells in PNH
Prevents damage of renal cells in IgAN and C3G
Used for the study of complement-mediated diseases
Particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)

Pricing & Availability

3,731

Medchemexpress LLC 7H-pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(trimethylphenyl) hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 50 MG

Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a white to light yellow solid for preclinical research. It is used to study stress-response pathways, CRH/CRF signaling, anxiety-like behavior, and inflammation models. The compound is provided at high purity and supplied in small mg-scale pack sizes suitable for laboratory use.

Non-peptide CRHR1 antagonist used in stress and neuroendocrine research.
High purity for reliable experimental results.
Solid form, easy to weigh and formulate.
Available in mg-scale pack sizes for preclinical studies.
Includes datasheet, certificate of analysis, and safety data sheet documentation.

Pricing & Availability

3,732

Medchemexpress LLC TG 100572 Hydrochloride | 867331-64-4 | 98.8% | 512.43 | 5 MG

TG 100572 Hydrochloride is a multi-targeted kinase inhibitor that effectively targets receptor tyrosine kinases and Src kinases, making it suitable for various research applications.

Multi-targeted kinase inhibitor
Inhibits receptor tyrosine kinases and Src kinases
Potently inhibits VEGFR1, VEGFR2, FGFR1, FGFR2, and PDGFRβ
Suppresses vascular endothelial cell proliferation
Blocks VEGF-induced phosphorylation of extracellular signal-regulated kinase
Induces apoptosis in rapidly proliferating endothelial cell cultures

Pricing & Availability

3,733

Medchemexpress LLC Fadrozole hydrochloride hemihydrate | 176702-70-8 | 99.6% | 268.74 | 25 MG

Fadrozole hydrochloride hemihydrate is an orally active, potent, selective, and nonsteroidal aromatase inhibitor, with an IC50 of 6.4 nM. It inhibits the production of estrogen and progesterone, with IC50 values of 0.03 and 120 μM, respectively. This compound shows prevention of spontaneous tumors and can be used for research on estrogen-dependent diseases and cancer.

Orally active
Potent, selective, and nonsteroidal aromatase inhibitor (IC50 of 6.4 nM)
Inhibits estrogen production (IC50 of 0.03 μM)
Inhibits progesterone production (IC50 of 120 μM)
Prevents spontaneous tumors
Useful for research of estrogen-dependent diseases and cancer

Pricing & Availability

3,734

Medchemexpress LLC AMXI-5001 hydrochloride | 00-00-0 | 98.1% | C25H21ClFN5O3 | 10MG

AMXI-5001 hydrochloride is a research-grade small molecule described as a dual inhibitor of PARP1/2 and microtubule polymerization. It shows potent cellular activity against PARP and tubulin targets, with reported favorable metabolic stability and oral bioavailability, and is intended for preclinical anticancer research.

Dual mechanism: inhibits PARP1/2 and tubulin polymerization.
Potent PARP inhibition with low nanomolar IC50s and tubulin inhibition in the micromolar range.
Orally bioavailable with favorable pharmacokinetic properties.
Suitable for in vitro and in vivo anticancer studies.
High purity for research applications.

Pricing & Availability

3,735

Medchemexpress LLC Akalumine (hydrochloride) | 2558205-28-8 | 99.92% | 338.85 | 25 MG

AkaLumine hydrochloride is a D-luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc, offering high tissue-penetration and increased detection sensitivity for deep-tissue targets. It is intended for research use only and not for sale to patients.

D-luciferin analogue
Km of 2.06 μM for recombinant firefly luciferase protein
Emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc
High tissue-penetration
Increases detection sensitivity from deep-tissue targets

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | MFCD00868190 | 99.9% | 337.24 g·mol⁻¹ | C17H18Cl2N2O | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LY3020371 hydrochloride | 1377615-44-5 | 99.2% | 395.81 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iptacopan hydrochloride | 1646321-63-2 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TG 100572 Hydrochloride | 867331-64-4 | 98.8% | 512.43 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fadrozole hydrochloride hemihydrate | 176702-70-8 | 99.6% | 268.74 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 00-00-0 | 98.1% | C25H21ClFN5O3 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Akalumine (hydrochloride) | 2558205-28-8 | 99.92% | 338.85 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More