Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,096 – 4,110 of 6,662 results

4,096

Medchemexpress LLC VU0453379 hydrochloride | 98.0% | 471.03 | 25 MG

VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.

Highly selective
CNS penetrant
Positive allosteric modulator (PAM) of GLP-1R

Pricing & Availability

4,097

Medchemexpress LLC Amxi-5001 hydrochloride | 98.05% | C25H21ClFN5O3 | 50 MG

AMXI-5001 hydrochloride is a potent, orally active compound that acts as a dual inhibitor of parp1/2 and microtubule polymerization. It demonstrates selective antitumor cytotoxicity across various human cancer cells, with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors. AMXI-5001 hydrochloride has been shown to induce complete regression of established tumors, including large ones.

Potent, orally active, dual parp1/2 and microtubule polymerization inhibitor.
Exhibits selective antitumor cytotoxicity in a wide range of human cancer cells.
Shows much lower IC50s than current clinical PARP1/2 inhibitors.
Capable of inducing complete regression of established tumors, including exceedingly large tumors.

Pricing & Availability

4,098

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.8% | C24H30ClNO3 | 1 G

Donepezil Hydrochloride (E2020) is a reversible, selective Acetylcholinesterase (AChE) inhibitor. It demonstrates high selectivity for AChE over Butyrylcholinesterase (BuChE) and exhibits neuroprotective effects against Aβ42 neurotoxicity. Its IC50 for AChE activity is 6.7 nM.

Reversible, selective AChE inhibitor
High selectivity for AChE over BuChE
Exhibits neuroprotective effects against Aβ42 neurotoxicity

Pricing & Availability

4,099

Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | MFCD04038020 | 98.43% | C19H18ClN5O7S3 | 100 MG

Ceftiofur hydrochloride is an inhibitor of bacterial cell wall synthesis that targets bacterial penicillin-binding proteins (PBPs). It exhibits anti-inflammatory effects in endotoxemia. Its bactericidal action stems from inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Additionally, Ceftiofur hydrochloride can inhibit the activation of NF-κB and MAPKs, which consequently reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Targets bacterial penicillin-binding proteins (PBPs).
Exhibits bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis.
Leads to bacterial cell lysis.
Possesses anti-inflammatory properties by inhibiting NF-κB and MAPK activation.
Reduces the secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6).

Pricing & Availability

4,100

Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | 97.0% | 379.88 | 5 MG

BMY-25368 (SKF 94482) is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. It competitively antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food. This product is for research use only and not intended for medical applications.

Acts as a histamine H2 receptor antagonist
Inhibits gastric acid secretion
Antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food
Light yellow to yellow solid
Suitable for laboratory research

Pricing & Availability

4,101

Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG

Adrogolide hydrochloride is a research-grade prodrug converted rapidly in plasma to the dopamine D1 receptor agonist A-86929. Supplied as the hydrochloride salt, it is intended for laboratory research use only and is provided in pre-weighed quantities for assay preparation.

High purity (≈99.6%) suitable for research applications.
Molecular weight 435.96 and formula C22H26ClNO4S.
Available in pre-weighed small quantities for in vitro and in vivo studies.
Soluble in DMSO for assay preparation.
Acts as a prodrug to the D1 receptor agonist A-86929.

Pricing & Availability

4,102

Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | 99.9% | 349.85 | C19H24ClNO3 | 50 MG

Oxyfedrine hydrochloride is an orally active β-adrenoreceptor agonist and coronary vasodilator supplied as the hydrochloride salt for research use. It is intended for pharmacological and cardiovascular studies and should be stored and handled according to supplier recommendations.

High purity for research applications (99.9% as listed).
Molecular formula C19H24ClNO3 and molecular weight 349.85.
Supplied as a solid, facilitating handling and formulation.
Storage: sealed, away from moisture and light; in solvent -80°C (6 months) or -20°C (1 month).
Suitable for studies of β-adrenergic activity and coronary vasodilation.

Pricing & Availability

4,103

Medchemexpress LLC Claramine (hydrochloride) | 99.6% | 625.45 | 5 MG

Claramine hydrochloride is a steroid polyamine with blood-brain barrier permeability. It can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins.

Steroid polyamine
Blood-brain barrier permeability
Regulates properties of lipid membranes
Protects cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins

Pricing & Availability

4,104

Medchemexpress LLC Nimustine (hydrochloride) | 55661-38-6 | 98.2% | 309.15 | 25 MG

Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent, inducing DNA double-strand breaks and inter-strand crosslinks. This action activates the DNA damage response signaling pathway and the p38 MAPK/JNK signaling pathway, demonstrating antitumor activity.

Acts as an alkylating agent
Induces DNA double-strand breaks and inter-strand crosslinks
Activates DNA damage response signaling pathway
Activates p38 MAPK/JNK signaling pathway
Exhibits antitumor activity
Induces apoptosis in LN-229 cells
Inhibits tumor growth in C3H/HeN mouse models

Pricing & Availability

4,105

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.65% | C23H21Cl3N6O3S | 50 MG

SGK1-IN-3 hydrochloride (compound 3a) is a potent SGK1 inhibitor with an IC50 of <1 μM, and it has the potential for the research of osteoarthritis. This product is for research use only and not for sale to patients.

Potent SGK1 inhibitor
Potential for osteoarthritis research
Purity of 96.65%
Solid appearance with light yellow to yellow color
Molecular weight of 567.88
Soluble in DMSO at 125 mg/mL

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4,106

Medchemexpress LLC VATINOXAN HYDROCHLO 10MM/1ML

VATINOXAN HYDROCHLO 10MM/1ML

Pricing & Availability

4,107

Medchemexpress LLC Buspirone (hydrochloride) | 33386-08-2 | 99.99% | 250 MG

Buspirone hydrochloride is a 5-HT1A receptor agonist used in anxiety and depression research. It has been shown to have cytotoxic effects in lymphocytes and can induce ROS formation, MMP collapse, lipid peroxidation, lysosomal damage, and elevation of glutathione disulfide (GSSG) in these cells. In mice, it has been observed to reduce anxiety/depression behaviors, restore IS-shifted β-diversity in gut microbiota, and reduce inflammation markers in the hippocampus and colon.

5-HT1A receptor agonist
Used for anxiety and depression research
Can reduce anxiety/depression behaviors in mice
Restores IS-shifted β-diversity in the gut microbiota in mice
Reduces TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus and myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon in mice

Pricing & Availability

4,108

Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 25 MG

Alosetron Hydrochloride is a potent and highly selective serotonin 5-HT3 receptor antagonist used for the research of irritable bowel syndrome (IBS). It blocks fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, and attenuates visceral nociceptive effects.

Potent and highly selective serotonin 5-HT3 receptor antagonist
Used for research of irritable bowel syndrome (IBS)
Blocks fast 5HT3-mediated depolarization of myenteric and submucosal neurons
Attenuates visceral nociceptive effect of rectal distension
Exhibits anti-inflammatory effects

Pricing & Availability

4,109

Medchemexpress LLC CZC-54252 (hydrochloride) | 1784253-05-9 | 98.4% | 25 MG

CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor. It attenuates G2019S LRRK2-induced human neuronal injury and exhibits neuroprotective activity. This product is a solid, typically light yellow to orange in appearance.

Potent and selective LRRK2 inhibitor
Attenuates G2019S LRRK2-induced human neuronal injury
Exhibits neuroprotective activity
Molecular weight: 541.45
Formula: C22H26Cl2N6O4S
Appearance: Solid, light yellow to orange
Stable under recommended storage conditions
Soluble in DMSO

Pricing & Availability

4,110

Medchemexpress LLC SB-743921 hydrochloride | 940929-33-9 | 99.8% | 553.52 | 10 MG

SB-743921 hydrochloride is a potent inhibitor of the mitotic kinesin KSP (Eg5), with a Ki of 0.1 nM.

Potently inhibits colony-forming cell (CFC) formation of chronic myeloid leukemia (CML) primary cells.
Exhibits slight inhibitory activities on the colony-forming ability of normal bone marrow progenitors.
Induces apoptosis of CML primary CD34+ cells, with slight effect on normal CD34+ cells.
Displays additive anti-proliferative effect in KCL22 and CML CD34+ cells when combined with imatinib.
Overcomes imatinib resistance in CML cells.
Inhibits MEK/ERK and AKT signaling in CML cells.
Has good oral bioavailability and pharmacokinetics.
Induces complete tumor regression in nude mice bearing lung cancer patient xenografts.

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Alcohols and polyols

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Medchemexpress LLC VU0453379 hydrochloride | 98.0% | 471.03 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amxi-5001 hydrochloride | 98.05% | C25H21ClFN5O3 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.8% | C24H30ClNO3 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | MFCD04038020 | 98.43% | C19H18ClN5O7S3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | 97.0% | 379.88 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | 99.9% | 349.85 | C19H24ClNO3 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Claramine (hydrochloride) | 99.6% | 625.45 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nimustine (hydrochloride) | 55661-38-6 | 98.2% | 309.15 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.65% | C23H21Cl3N6O3S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VATINOXAN HYDROCHLO 10MM/1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Buspirone (hydrochloride) | 33386-08-2 | 99.99% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CZC-54252 (hydrochloride) | 1784253-05-9 | 98.4% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-743921 hydrochloride | 940929-33-9 | 99.8% | 553.52 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More