Alcohols and polyols
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- (30)
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- (20)
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- (395)
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- (102)
- (21)
- (50)
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- (61)
- (13)
- (14)
- (1)
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- (1)
- (26)
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- (1)
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- (1)
- (462)
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- (46)
- (11)
- (45)
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- (1)
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- (145)
- (114)
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- (1)
- (28)
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- (1)
- (36)
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- (33)
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- (7)
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- (1)
- (26)
- (1)
- (1)
- (1)
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- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
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- (2)
- (7)
- (12)
- (1)
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- (24)
- (1)
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- (1)
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- (1)
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- (1)
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- (24)
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- (1)
- (1)
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- (11)
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- (1)
- (1)
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- (1)
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- (82)
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Filtered Search Results
Apexbio Technology LLC Alisol B 23-acetate 26575-95-1 20mg
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Alisol B 23-acetate (CAS 26575-95-1) is a small molecule farnesoid X receptor (FXR) agonist FXR a nuclear receptor regulating transcriptional responses to bile acids is implicated in hepatocyte proliferation and liver regeneration In cellular assays using HepG2 cells cotransfected with FXR and a bile salt export pump (BSEP) reporter construct Alisol B 23-acetate increased FXR-mediated transcription in a dose-dependent manner with maximal (4 3-fold) induction at 10 M In murine models of partial hepatectomy oral administration of Alisol B 23-acetate enhanced liver regrowth DNA synthesis and mitotic index This compound serves as a valuable tool for investigating FXR signaling in liver regeneration research
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eMolecules CYCLOHEXANOL 5MG
5000191605 CYCLOHEXANOL 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430591 GINSENOSIDE RB1 100MG
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Medchemexpress LLC Calcifediol-d3 | 140710-94-7 | 99.0% | 403.66 | 5 MG
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Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC HY-N2241 5mg Medchemexpress, Hosenkoside F CAS:160896-45-7 Purity:>98%
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Medchemexpress, HY-N2241 5mg Hosenkoside F CAS:160896-45-7 Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 3-epi-Vitamin D3 (Epicholecalciferol) | 57651-82-8 | C27H44O | 50 MG
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3-epi-Vitamin D3 (Epicholecalciferol) is an analogue of Vitamin D3. It functions as a Hedgehog pathway inhibitor with an IC50 of 39.2 μM in U87MG cells. This product is intended for research use only and is not for patient use.
- Acts as a Hedgehog pathway inhibitor
- Exhibits antiproliferative activity against U87MG cells
- Significantly upregulates Cyp24A1 in U87MG, HT-29 and C3H10T1/2 cells
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Medchemexpress LLC Ginsenoside Ra3 | 90985-77-6 | 5 MG
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Ginsenoside Ra3 is a natural product isolated from *Panax ginseng* that possesses anti-cancer activity.
- Isolated from Panax ginseng
- Possesses anti-cancer activity
- Purity: 99.75%
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Medchemexpress LLC 1α-hydroxy-3-epi-vitamin D3 | 58028-00-5 | 99.3% | 400.64 | C27H44O2 | 5 MG
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1α-Hydroxy-3-epi-vitamin D3 is a research-grade metabolite of 1α,25-dihydroxyvitamin D3 that acts as a potent suppressor of parathyroid hormone (PTH) secretion. It is provided as a highly pure compound with defined physicochemical properties for biochemical and pharmacological studies; handle and store according to supplier guidance.
- Natural metabolite of 1α,25-dihydroxyvitamin D3.
- Potent suppressor of parathyroid hormone secretion.
- High purity (99.3%) suitable for research applications.
- Molecular formula C27H44O2; molecular weight 400.64.
- Soluble in DMSO (50 mg/mL); store sealed, away from moisture and light.
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Medchemexpress LLC 25(R,S)-Ruscogenin | 874485-32-2 | 5 MG
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25(R,S)-Ruscogenin is a PI3K/Akt/mTOR signaling pathway inhibitor and TLR4 signaling inhibitor. It has been shown to suppress hepatocellular carcinoma (HCC) metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF, and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway. Additionally, Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.
- Molecular weight is 430.62.
- Formula is C27H42O4.
- Appears as a white to off-white solid.
- Classified as a steroid.
- Initial sources include plants (Liliaceae Liriope platyphylla Wang et Tang) and microorganisms (Bacillus megaterium CGMCC 1.1741).
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Medchemexpress LLC Jervine (11-Ketocyclopamine) | 469-59-0 | 425.60 | 100 MG
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Jervine (11-Ketocyclopamine) is a natural teratogenic steroidal alkaloid derived from *Veratrum nigrum*. It acts as a potent Hedgehog (Hh) inhibitor and exhibits anti-inflammatory and antioxidant properties.
- Potent Hedgehog (Hh) inhibitor
- Natural steroidal alkaloid
- Possesses anti-inflammatory properties
- Exhibits antioxidant properties
- Inhibits Akt phosphorylation and NF-κB activation
- Decreases COX-2 overexpression
- Induces apoptosis in vitro
- Demonstrates anti-inflammatory effects in vivo
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Medchemexpress LLC Gypenoside A | 157752-01-7 | 5 MG
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Gypenoside A is an orally active triterpenoid compound isolated from Gynostemma pentaphyllum. It possesses anti-inflammatory and antioxidant activities, and offers a protective effect on cardiomyocytes while inhibiting apoptosis. This compound is suitable for research in cardiovascular diseases and inflammation-related conditions.
- Possesses anti-inflammatory activities
- Possesses antioxidant activities
- Offers a protective effect on cardiomyocytes
- Can inhibit apoptosis
- Suitable for research in cardiovascular diseases
- Suitable for research in inflammation-related conditions
- Reduces secretion of cytokines and chemokines
- Inhibits ROS production
- Increases cell viability
- Activates the AMPK/Foxo1 signaling pathway
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Medchemexpress LLC Ursolic acid acetate | 7372-30-7 | 5 MG
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Ursolic acid acetate is a triterpenoid compound that acts as an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a KD of 8.16 μM. It exhibits cytotoxicity to KB cells with an IC50 value of 8.4 μM. It has potential applications in tumor and antimalarial research. It can reduce the ATPase activity of PfHsp90 in a dose-dependent manner and shows an IC50 of 24.93 μM against the P. falciparum FcB1 strain.
- Inhibitor of Plasmodium falciparum heat shock protein 90
- Cytotoxic to KB cells with an IC50 value of 8.4 μM
- Potential applications in tumor and antimalarial research
- Reduces ATPase activity of PfHsp90 in a dose-dependent manner
- Exhibits IC50 of 24.93 μM against P. falciparum FcB1 strain
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Medchemexpress LLC HY-N0605 5mg Medchemexpress, Ginsenoside Rh2 CAS:78214-33-2 Purity:>98%
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Medchemexpress, HY-N0605 5mg Ginsenoside Rh2 CAS:78214-33-2 Ginsenoside Rh2 is isolated from the root of Ginseng. Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9 . Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Gypenoside XIII | 80325-22-0 | 5 MG
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Gypenoside XIII is a natural product from the gypenosides family, extracted from Gynostemma pentaphyllum (Jiaogulan). It has a molecular weight of 754.99 and a formula of C41H70O12, appearing as a white to off-white solid with 99.13% purity. This triterpene is known for its various pharmacological properties.
- Protects against cardiovascular diseases, particularly atherosclerosis.
- Soluble in ethanol at 50 mg/mL, requiring sonication.
- Storage at 4°C, protected from light.
- In solvent, stable for 6 months at -80°C or 1 month at -20°C, protected from light.
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Medchemexpress LLC Ginsenoside Rk1 | 494753-69-4 | MFCD28124355 | 99.9% | 767.00 g/mol | C42H70O12 | 10 MG
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Ginsenoside Rk1 is a bioactive triterpenoid saponin derived from heat-processed Panax ginseng, provided as a research-grade analytical standard for biochemical and pharmacological studies.
- High purity research standard (99.9%).
- Molecular formula C42H70O12 and molecular weight 767.00 g/mol.
- Solid, white to light yellow appearance.
- Storage: solid at -20°C; in solvent, -80°C for 6 months and -20°C for 1 month (protect from light).
- Available as a 10 mg package suitable for analytical applications.
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