Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,621 – 4,635 of 6,661 results

4,621

Medchemexpress LLC Ap-III-a4 hydrochloride | 2070014-95-6 | 99.9% | 631.18 g/mol | C31H44ClFN8O3 | 10 MG

AP-III-a4 hydrochloride is a small-molecule, nonsubstrate analogue inhibitor of enolase supplied as the hydrochloride salt for research use. It is reported to bind and inhibit enolase (IC50 0.576 μM) and has been used in studies of cancer cell viability, migration, invasion, apoptosis, and glucose metabolism.

Nonsubstrate analogue enolase inhibitor (IC50 0.576 μM).
Used in cancer and diabetes research, including HCT116 cell assays.
Shown to inhibit cell migration and invasion and to induce apoptosis.
Increases glucose uptake and inhibits PEPCK expression in cell studies.
Supplied as a hydrochloride solid suitable for laboratory assays, commonly available in small quantities such as 10 MG.
Analytical documentation typically available (HPLC, LCMS, certificate of analysis).

Pricing & Availability

4,622

Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG

SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus. It is intended for research use only.

Orally active
Selective and reversible α7 n-AChRs partial agonist
Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus
Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes (IC50>5 μM)
Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.)

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4,623

Medchemexpress LLC EPZ011989 hydrochloride | 2095432-26-9 | 99.4% | 642.27 | 5 MG

EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. It shows anti-tumor activity and is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Potent and orally active Zeste Homolog 2 (EZH2) inhibitor
Ki value of <3 nM
Shows anti-tumor activity
Click chemistry reagent
Contains an Alkyne group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

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4,624

Medchemexpress LLC Ponatinib (hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 10 MG

Ponatinib hydrochloride is a hydrochloride of ponatinib, an orally active multi-targeted kinase inhibitor. It targets Abl, PDGFRα, VEGFR2, FGFR1, and Src with various IC50s.

Reduces the viability, migration, and function of human endothelial cells.
Decreased cell viability in HUVEC cells in a dose-dependent manner.
Increased the percentage of annexin/PI labeled cells in HUVEC cells.
Reduced VEGF-induced migration in HUVEC cells.
Protects mice from lethal influenza infection by inhibiting cytokine storm.
Treated mice had higher survival rates and reduced the infiltration of neutrophils.

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4,625

Medchemexpress LLC Vatinoxan hydrochloride | 130466-38-5 | 99.79% | 454.97 | 25 MG

Vatinoxan hydrochloride is a peripheral α2 adrenergic receptor antagonist. It has been shown to increase cardiac index and tissue oxygen delivery without deleterious adverse effects when administered alone. Furthermore, it attenuates or prevents dexmedetomidine's systemic hemodynamic effects in a dose-dependent manner and shortens the sedative effect without altering its quality. This product is intended for research use only.

Peripheral α2 adrenergic receptor antagonist.
Increases cardiac index and tissue oxygen delivery.
Attenuates or prevents dexmedetomidine's systemic hemodynamic effects.
Shortens sedative effect without altering its quality.
Intended for research use only.

Pricing & Availability

4,626

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG

Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor supplied as the hydrochloride salt for laboratory pharmacology studies. It has demonstrated neuroprotective and cognitive effects in preclinical models and is suitable for both in vitro assays and in vivo formulations. This material is intended for research use only and should be handled and stored to minimize moisture exposure.

Purity 99.4%.
Molecular weight 524.08 g/mol.
Chemical formula C24H34ClN5O4S.
Soluble in DMSO at 100 mg/mL with sonication.
Formulatable for in vivo dosing at ≥2.5 mg/mL in recommended vehicles.
Store sealed and protected from moisture and light; freeze solutions for longer-term storage.

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4,627

Medchemexpress LLC Voruciclib hydrochloride | 1000023-05-1 | 99.2% | 506.30 g·mol⁻1 | C22H20Cl2F3NO5 | 10MM 1ML

Voruciclib hydrochloride is an orally active, selective cyclin-dependent kinase inhibitor that potently inhibits CDK9 and represses MCL-1 transcription; it is provided for research use in solution and solid formats for cellular and biochemical studies.

Selectively inhibits CDK9 with low-nanomolar potency.
Represses MCL-1 expression in cellular models.
Supplied as a 10 mM solution in DMSO and in solid mass quantities.
High purity suitable for research applications.
Molecular weight 506.30 g·mol⁻1; formula C22H20Cl2F3NO5.
Intended for use in cell biology and oncology research.

Pricing & Availability

4,628

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.58% | 437.90 | 50 MG

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.

Inhibits topoisomerase II activity.
Induces site-selective DNA DSB.
Causes G2 arrest.
Leads to apoptosis.
Shows potent cytotoxic activity in AML cell lines.
Exhibits additive or synergistic activity with cytarabine in acute leukemia cell lines.
Reduces bone marrow cellularity in mice.
Causes reversible decrease in myeloid and lymphoid cells in vivo.

Pricing & Availability

4,629

Medchemexpress LLC GGTI-2154 (hydrochloride) | 478908-50-8 | 98.1% | 456.97 | 25 MG

GGTI-2154 hydrochloride is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. It demonstrates over 200-fold selectivity for GGTase I compared to FTase (IC50=5600 nM). This product is suitable for cancer research. It is for research use only and not sold to patients.

Potent and selective inhibitor of geranylgeranyltransferase I (GGTase I) with an IC50 of 21 nM.
Shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM).
Can be used for cancer research.
Induces breast tumor regression in MMTV-ν-Ha-Ras transgenic mice (100 mg/kg/day; s.c. for 14 days).
Inhibits A-549 tumor growth in nude mice by 60% (50 mg/kg/day; i.p. for 50 days).

Pricing & Availability

4,630

Medchemexpress LLC Riviciclib hydrochloride | 920113-03-7 | 99.08% | 438.30 | 25 MG

Riviciclib hydrochloride is a potent cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively. This compound shows antitumor activity on cisplatin-resistant cells.

IC50 & Target information available
In vitro studies show activity in various cancer cell lines
In vivo studies demonstrate significant inhibition of tumor growth

Pricing & Availability

4,631

Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 50 MG

AR-C102222 hydrochloride is a selective inducible nitric oxide synthase (iNOS) inhibitor (IC50 = 37 nM) provided as the hydrochloride salt for research use. It exhibits reported antinociceptive and anti-inflammatory activity and is supplied as a high-purity solid suitable for in vitro and in vivo studies.

Purity 99.83%.
Molecular weight 418.83 g/mol.
Chemical formula C19H17ClF2N6O.
Soluble in DMSO (100 mg/mL); formulatable for in vivo dosing (≥5 mg/mL in recommended vehicles).
Storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
Available as solid in multiple sizes, including 50 mg.

Pricing & Availability

4,632

Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML

Ro 41-1049 hydrochloride is a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied for research use. It is available as a solid and as a pre-made 10 mM solution in DMSO (1 mL), and is provided with a high reported purity to support reproducible in vitro experiments.

Reversible, selective MAO-A inhibition suitable for biochemical assays.
Supplied as solid or pre-made 10 mM solution in DMSO (1 mL) for convenience.
High reported purity to reduce confounding impurities.
Characterized by CAS number 127917-66-2 and known molecular weight for accurate dosing.
Intended for research use only; not for human or clinical use.

Pricing & Availability

4,633

Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 25 MG

Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide, a potent and selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE-1) used for research applications. It is provided as a high-purity solid suitable for in vitro and ex vivo studies of NHE-1 function and related cardiovascular and platelet biology.

Potent and selective NHE-1 inhibition (human IC50 ~14 nM).
Inhibits ex vivo NHE-1-dependent platelet swelling (IC50 ~59 nM).
High purity (>99% by HPLC).
Available as the hydrochloride hydrate salt for improved handling and stability.
Molecular weight 374.82 g/mol; molecular formula C17H19ClN6O2.
Supplied in small research quantities, e.g., 25 MG.

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4,634

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.7% | C23H21Cl3N6O3S | 25 MG

SGK1-IN-3 hydrochloride is a potent SGK1 inhibitor with an IC50 of less than 1 μM. It has the potential for the research of osteoarthritis.

Potent SGK1 inhibitor with an IC50 of <1 μM
Potential for osteoarthritis research

Pricing & Availability

4,635

Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | 99.9% | 349.85 | C19H24ClNO3 | 25 MG

Oxyfedrine hydrochloride is the hydrochloride salt of oxyfedrine, an orally active beta-adrenoreceptor agonist and vasodilator used in pharmacological research. Supplied as a solid research-grade powder, it includes batch analytical data to support experimental use and handling.

High purity powder (~99.9%).
Acts as a beta-adrenoreceptor agonist and vasodilator for pharmacology studies.
Solid form with defined molecular weight and formula for dosing calculations.
Stable when stored sealed, protected from moisture and light.
Provided with batch-specific analytical documents (COA, HNMR, LCMS).

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Alcohols and polyols

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Medchemexpress LLC Ap-III-a4 hydrochloride | 2070014-95-6 | 99.9% | 631.18 g/mol | C31H44ClFN8O3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ011989 hydrochloride | 2095432-26-9 | 99.4% | 642.27 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ponatinib (hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Vatinoxan hydrochloride | 130466-38-5 | 99.79% | 454.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voruciclib hydrochloride | 1000023-05-1 | 99.2% | 506.30 g·mol⁻1 | C22H20Cl2F3NO5 | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.58% | 437.90 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GGTI-2154 (hydrochloride) | 478908-50-8 | 98.1% | 456.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Riviciclib hydrochloride | 920113-03-7 | 99.08% | 438.30 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SGK1-IN-3 hydrochloride | 96.7% | C23H21Cl3N6O3S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | 99.9% | 349.85 | C19H24ClNO3 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More