Alcohols and polyols
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- (1)
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- (1)
- (1)
- (1)
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- (30)
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- (20)
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- (4)
- (5)
- (395)
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- (102)
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- (13)
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- (1)
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- (1)
- (26)
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- (4)
- (1)
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- (1)
- (462)
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- (11)
- (45)
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- (1)
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- (145)
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- (1)
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- (1)
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- (2)
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- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
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- (2)
- (5)
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- (17)
- (15)
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- (2)
- (5)
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- (33)
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- (2)
- (2)
- (8)
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- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
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- (1)
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- (1)
- (17)
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- (1)
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- (24)
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- (1)
- (1)
- (1)
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- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
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- (6)
- (11)
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- (3)
- (1)
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- (14)
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- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
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- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (2)
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- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
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- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
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- (40)
- (21)
- (1)
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- (1)
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- (20)
- (2)
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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000724498 SB 243213 HYDROCHLO 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000738957 25E-NBOME HYDROCHLO 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000739060 25E-NBOME HYDROCHLO 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000744527 FILANESIB HYDROCHLO 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000745796 TOPOTECAN HYDROCHLO 25MG
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Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | C24H30ClNO3 | 500 MG
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Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. It shows high selectivity for AChE over BuChE and exhibits a neuroprotective effect on Aβ42 neurotoxicity. Its neuroprotective mechanism is related to the enhanced phosphorylation of Akt and GSK-3β and reduced phosphorylation of tau and glycogen synthase.
- Reversible, selective AChE inhibitor
- Shows high selectivity for AChE over BuChE
- Exhibits neuroprotective effect on Aβ42 neurotoxicity
- Neuroprotective mechanism is related to enhanced phosphorylation of Akt and GSK-3β
- Reduced phosphorylation of tau and glycogen synthase
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Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | 99.9% | C11H14ClN | 1 ML
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Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM for MAO-A and 0.5 μM for MAO-B. It exhibits antihypertensive and anticancer activities. Pargyline (hydrochloride) is also a click chemistry reagent, containing an Alkyne group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that have Azide groups.
- Irreversible monoamine oxidase (MAO) inhibitor
- Inhibits MAO-A with a Ki of 13 μM
- Inhibits MAO-B with a Ki of 0.5 μM
- Demonstrates antihypertensive activities
- Exhibits anticancer activities
- Functions as a click chemistry reagent
- Contains an Alkyne group for CuAAc reactions
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Medchemexpress LLC Prasugrel hydrochloride | 389574-19-0 | C20H21ClFNO3S | 500 MG
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Prasugrel hydrochloride (PCR 4099 hydrochloride) is a thienopyridine and a proagent that inhibits platelet function. It is an orally active and potent P2Y12 receptor antagonist, which works by inhibiting ADP-induced platelet aggregation. In rat platelets, the active metabolite of Prasugrel hydrochloride inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM.
- Exhibits faster and significantly more potent antiplatelet effects in vivo compared to Clopidogrel.
- Requires in vivo metabolic processing as an inactive prodrug to generate its active antiplatelet metabolite.
- Rapidly absorbed from the gut following oral administration.
- Achieves maximum plasma levels of active metabolite within 1 hour.
- Leads to effective, maximum inhibition of platelet aggregation within 1-2 hours.
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Medchemexpress LLC PRT062607 hydrochloride (P505-15 hydrochloride) | 1370261-97-4 | C19H24ClN9O | 1 ML
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PRT062607 Hydrochloride (P505-15 Hydrochloride) is an orally available Syk inhibitor with an IC50 of 1 nM. It inhibits inflammation and induces apoptosis, demonstrating potent antitumor activity in tumor xenograft mouse models. In vitro, it also exhibits significant activity against a variety of kinases, including Fgr, MLK1, Yes, Flt3, PAK5, Lyn, cSRC, Lck, Pyk, and FAK.
- Inhibits phosphorylation of ERK(Y204), AKT(S473), and SYK(Y352) in Ramos cells
- Inhibits BLNK Tyr84 phosphorylation
- Induces apoptosis in human whole blood
- Shows dose-dependent anti-inflammatory activity in rodent models of rheumatoid arthritis
- Inhibits B-cell activation
- Prevents tumor formation in mouse xenograft models
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | MFCD03427293 | 99.9% | 403.90 | 100 MG
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Bambuterol hydrochloride, also known as (±)-Bambuterol hydrochloride, is a long-acting beta-adrenoceptor agonist (LABA). It is primarily utilized in the treatment of asthma and functions as a proagent of terbutaline. Intended for research use only, this product is contraindicated in pregnancy and for individuals with severely impaired liver function, requiring dose adjustments for renal impairment.
- Used in the treatment of asthma.
- Functions as a proagent of terbutaline.
- Intended for research use only.
- Purity of 99.9%.
- Available in solid form.
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Medchemexpress LLC SRI-011381 hydrochloride | 2070014-88-7 | 99.6% | 365.94 | C20H32ClN3O | 200 MG
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SRI-011381 hydrochloride is an orally active TGF-β signaling agonist reported to exhibit neuroprotective effects in vitro and in vivo. It is supplied as a solid or as a DMSO solution for research use and is provided at high chemical purity.
- Orally active TGF-β signaling agonist.
- Promotes proliferation of mouse lung fibroblasts in vitro.
- Increases TGF-β1, NALP3, collagen-1, and α-SMA expression.
- Demonstrates neuroprotective effects in animal models, reducing inflammation and neuron loss.
- Available as a solid and as 10 mM solution in DMSO in multiple package sizes.
- High purity suitable for research applications.
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Medchemexpress LLC 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy- | 485-47-2 | 100.0 % | 100 G
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Ninhydrin is a chromogenic analytical probe used for the quantification of amino acids and proteins. It reacts with primary and secondary amines, producing a blue or purple reaction product, diketohydrindylidene-diketohydrindamine. It is utilized in the amino acid analysis of proteins; most amino acids, excluding proline, can be hydrolyzed and react with ninhydrin, after which they are colorimetrically quantified following chromatographic separation.
- Chromogenic analytical probe.
- Reacts with primary and secondary amines.
- Solid appearance, white to light yellow color.
- Quantification of amino acids and proteins.
- Useful in amino acid analysis of proteins.
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Medchemexpress LLC Eperisone (hydrochloride) | 56839-43-1 | 99.95% | 1 G
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Eperisone hydrochloride is an orally active antispastic agent with a vasodilator effect. It is used for the research of muscle stiffness and pain. This compound is a potent and selective P2X7 receptor antagonist, also exhibiting antagonism for human P2X3. It works by relaxing both skeletal muscles and vascular smooth muscles, demonstrating several beneficial effects.
- Reduces myotonia.
- Improves circulation.
- Suppresses the pain reflex.
- Preferentially suppresses lung fibroblast activity.
- Suppresses bleomycin-dependent pulmonary fibrosis.
- Not toxic to alveolar epithelial cells in vitro.
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Medchemexpress LLC Proadifen (hydrochloride) | 62-68-0 | 99.95% | 1 ML
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Proadifen hydrochloride, also known as SKF-525A, is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. It reduces monoamine oxidase A activity and N,N-dimethyltryptamine metabolism. This compound is promising for research related to metabolism-related diseases, ovarian carcinoma, inflammation, and dopamine neuron-related diseases.
- Reduces monoamine oxidase A activity
- Reduces N,N-dimethyltryptamine metabolism in liver microsomes
- Inhibits N-demethylation and Acridone formation
- Augments lipopolysaccharide-induced fever
- Exacerbates prostaglandin E2 levels in rats
- Promising for research of metabolism-related diseases
- Promising for research of ovarian carcinoma
- Promising for research of inflammation
- Promising for research of dopamine neuron-related diseases
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Medchemexpress LLC Buspirone (hydrochloride) | 33386-08-2 | 99.99 % | 1 G
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Buspirone hydrochloride is a 5-HT1A receptor agonist that can be used for anxiety and depression research.
- Has cytotoxic effect in lymphocytes.
- Induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage, and elevation of glutathione disulfide (GSSG) in lymphocytes.
- Reduces anxiety/depression behaviors in C57BL/6N mice.
- Restores IS-shifted β-diversity in the gut microbiota in C57BL/6N mice.
- Reduced TNF-α expression and NF-κB+/Iba1+ cell population in the hippocampus.
- Reduced myeloperoxidase activity and NF-κB+/CD11c+ cell population in the colon.
- Reduced the IS- or EC-induced gut proteobacteria population.
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