Alcohols and polyols
- (1)
- (55)
- (350)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (155)
- (1)
- (63)
- (29)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
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- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (10)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
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- (1)
- (2)
- (2)
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- (1)
- (1)
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- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
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- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (81)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
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- (8)
- (1)
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- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
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- (1)
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- (3)
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- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (86)
- (1)
- (5)
- (72)
- (3)
- (5)
- (238)
- (4)
- (2)
- (2)
- (21)
- (281)
- (17)
- (1)
- (6)
- (279)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (731)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
- (3)
- (3)
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- (3)
- (2)
- (1)
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- (2)
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- (1)
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- (2)
- (2)
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- (1)
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- (2)
- (3)
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- (1)
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- (3)
- (3)
- (1)
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- (3)
- (3)
- (6)
- (5)
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- (3)
- (2)
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- (2)
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- (2)
- (2)
- (1)
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- (2)
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- (2)
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- (2)
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- (2)
- (3)
- (2)
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- (6)
- (2)
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- (1)
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- (2)
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- (2)
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- (1)
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- (2)
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- (3)
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- (3)
- (5)
- (2)
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- (2)
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- (2)
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- (3)
- (3)
- (2)
- (5)
- (2)
- (11)
- (1)
- (3)
- (4)
- (1)
- (6)
- (4)
- (2)
- (4)
- (1)
- (2)
- (5)
- (2)
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- (6)
- (2)
- (2)
- (3)
- (2)
- (2)
- (7)
- (2)
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- (6)
- (3)
- (2)
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- (3)
- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
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- (3)
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- (3)
- (2)
- (1)
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- (2)
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- (2)
- (3)
- (2)
- (3)
- (2)
- (3)
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- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
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- (1)
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- (6)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (2)
- (5)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
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- (2)
- (2)
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- (3)
- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
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- (2)
- (2)
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- (6)
- (3)
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- (3)
- (1)
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- (2)
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- (3)
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- (1)
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- (1)
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- (1)
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- (8)
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- (8)
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- (1)
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Filtered Search Results
Medchemexpress LLC VU0453379 hydrochloride | 98.0% | 471.03 | 25 MG
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.
- Highly selective
- CNS penetrant
- Positive allosteric modulator (PAM) of GLP-1R
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Amxi-5001 hydrochloride | 98.05% | C25H21ClFN5O3 | 50 MG
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AMXI-5001 hydrochloride is a potent, orally active compound that acts as a dual inhibitor of parp1/2 and microtubule polymerization. It demonstrates selective antitumor cytotoxicity across various human cancer cells, with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors. AMXI-5001 hydrochloride has been shown to induce complete regression of established tumors, including large ones.
- Potent, orally active, dual parp1/2 and microtubule polymerization inhibitor.
- Exhibits selective antitumor cytotoxicity in a wide range of human cancer cells.
- Shows much lower IC50s than current clinical PARP1/2 inhibitors.
- Capable of inducing complete regression of established tumors, including exceedingly large tumors.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Medchemexpress LLC Almorexant hydrochlo 100mg | 913358-93-7 | 100MG
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Almorexant (ACT 078573) hydrochloride is an orally active potent and competitive dual orexin receptor antagonist with Kd values of 1 3 nM (OX1) and 0 17 nM (OX2) respectively Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides Almorexant hydrochloride totally blocked the intracellular Ca2 signal pathway Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1 [2 [3 [4
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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG
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Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.
- Potent CCR5 antagonist
- Effective against wild-type R5 HIV-1 strains
- Suppresses HIV-1MDR variants
- Binds to CCR5 with high affinity
- Suppresses R5 HIV-1 viremia in animal models
- Investigated in clinical trials for HIV infection
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Medchemexpress LLC Claramine (hydrochloride) | 99.6% | 625.45 | 5 MG
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Claramine hydrochloride is a steroid polyamine with blood-brain barrier permeability. It can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins.
- Steroid polyamine
- Blood-brain barrier permeability
- Regulates properties of lipid membranes
- Protects cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins
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Medchemexpress LLC Nimustine (hydrochloride) | 55661-38-6 | 98.2% | 309.15 | 25 MG
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent, inducing DNA double-strand breaks and inter-strand crosslinks. This action activates the DNA damage response signaling pathway and the p38 MAPK/JNK signaling pathway, demonstrating antitumor activity.
- Acts as an alkylating agent
- Induces DNA double-strand breaks and inter-strand crosslinks
- Activates DNA damage response signaling pathway
- Activates p38 MAPK/JNK signaling pathway
- Exhibits antitumor activity
- Induces apoptosis in LN-229 cells
- Inhibits tumor growth in C3H/HeN mouse models
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Medchemexpress LLC Ap-III-a4 hydrochloride | 2070014-95-6 | 99.9% | 631.18 g/mol | C31H44ClFN8O3 | 10 MG
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AP-III-a4 hydrochloride is a small-molecule, nonsubstrate analogue inhibitor of enolase supplied as the hydrochloride salt for research use. It is reported to bind and inhibit enolase (IC50 0.576 μM) and has been used in studies of cancer cell viability, migration, invasion, apoptosis, and glucose metabolism.
- Nonsubstrate analogue enolase inhibitor (IC50 0.576 μM).
- Used in cancer and diabetes research, including HCT116 cell assays.
- Shown to inhibit cell migration and invasion and to induce apoptosis.
- Increases glucose uptake and inhibits PEPCK expression in cell studies.
- Supplied as a hydrochloride solid suitable for laboratory assays, commonly available in small quantities such as 10 MG.
- Analytical documentation typically available (HPLC, LCMS, certificate of analysis).
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Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG
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SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus. It is intended for research use only.
- Orally active
- Selective and reversible α7 n-AChRs partial agonist
- Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus
- Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes (IC50>5 μM)
- Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.)
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Medchemexpress LLC Vatinoxan hydrochloride | 130466-38-5 | 99.79% | 454.97 | 25 MG
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Vatinoxan hydrochloride is a peripheral α2 adrenergic receptor antagonist. It has been shown to increase cardiac index and tissue oxygen delivery without deleterious adverse effects when administered alone. Furthermore, it attenuates or prevents dexmedetomidine's systemic hemodynamic effects in a dose-dependent manner and shortens the sedative effect without altering its quality. This product is intended for research use only.
- Peripheral α2 adrenergic receptor antagonist.
- Increases cardiac index and tissue oxygen delivery.
- Attenuates or prevents dexmedetomidine's systemic hemodynamic effects.
- Shortens sedative effect without altering its quality.
- Intended for research use only.
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Medchemexpress LLC Riviciclib hydrochloride | 920113-03-7 | 99.08% | 438.30 | 25 MG
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Riviciclib hydrochloride is a potent cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively. This compound shows antitumor activity on cisplatin-resistant cells.
- IC50 & Target information available
- In vitro studies show activity in various cancer cell lines
- In vivo studies demonstrate significant inhibition of tumor growth
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Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML
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Ro 41-1049 hydrochloride is a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied for research use. It is available as a solid and as a pre-made 10 mM solution in DMSO (1 mL), and is provided with a high reported purity to support reproducible in vitro experiments.
- Reversible, selective MAO-A inhibition suitable for biochemical assays.
- Supplied as solid or pre-made 10 mM solution in DMSO (1 mL) for convenience.
- High reported purity to reduce confounding impurities.
- Characterized by CAS number 127917-66-2 and known molecular weight for accurate dosing.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 100 MG
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GYKI 53655 hydrochloride is a research-grade small molecule that acts as a non-competitive antagonist of AMPA and kainate receptors. It is supplied as a light yellow to yellow solid with reported purity of ~98.4% and molecular formula C19H21ClN4O3. Intended for in vitro research use only.
- Non-competitive AMPA and kainate receptor antagonist.
- High purity (~98.4%) for consistent experimental results.
- Light yellow to yellow solid, soluble in DMSO and water with recommended handling precautions.
- Recommended storage: solid at 4°C; prepared solutions at -80°C (up to 6 months) or -20°C (short term).
- Available in multiple solid sizes, including 100 mg, for lab-scale studies.
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Medchemexpress LLC Guanabenz hydrochloride | 23113-43-1 | 99.9% | 25 MG
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Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist with antihypertensive and antiparasitic activity. It interferes with ER stress-signalling and has protective effects in cardiac myocytes. It is also used for the research of high blood pressure. For research use only.
- Orally active alpha-2-adrenoceptor agonist
- Exhibits antihypertensive activity
- Displays antiparasitic activity
- Interferes with ER stress-signalling
- Has protective effects in cardiac myocytes
- Used for research of high blood pressure
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eMolecules 32638-88-3 | Pyrogallol red | Oakwood Chemicals | MFCD00005046 | 400.360 | C19H12O8S | 0.000 | Oc1ccc2c(Oc3c(O)c(O)ccc3C22OS(=O)(=O)c3ccccc23)c1O | 1g | 532150587
Pyrogallol red | Oakwood Chemicals | 32638-88-3 | MFCD00005046 | 400.360 | C19H12O8S | 0.000 | Oc1ccc2c(Oc3c(O)c(O)ccc3C22OS(=O)(=O)c3ccccc23)c1O | 1g | 532150587
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