Alcohols and polyols
Medchemexpress LLC 17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol | 86770-69-6 | MFCD22056309 | 98.0% | 307.34 g/mol | C12H25N3O6 | 1 G
Azido-PEG6-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a primary hydroxyl group, used as a click-chemistry reagent and linker in bioconjugation and PROTAC/ADC synthesis.
- Water-soluble PEG6 linker with azide and hydroxyl functional groups.
- Useful for copper-free and copper-catalyzed click reactions.
- Commonly used as a spacer/linker in antibody-drug conjugates and PROTACs.
- Molecular weight approximately 307.34 g/mol and formula C12H25N3O6.
- Available in small-scale laboratory quantities (e.g., 1 G) and typically supplied with high purity.
Medchemexpress LLC Ladostigil hydrochlo 5mg | 209394-18-3 | 5MG
Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with IC50s of 37 1 and 31 8 M for MAO-B and AChE respectively Ladostigil hydrochloride exhibits neuroprotective antioxidant and anti-inflammatory activities Ladostigil can be used for the research of depression and Alzheimer s disease[1 [2 Ladostigil (hydrochloride) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Apexbio Technology LLC Azido-PEG6-alcohol 86770-69-6 100mg
Azido-PEG6-alcohol (CAS 86770-69-6) is a polyethylene glycol-based compound featuring an azide functional group It serves as a versatile building block in bioorthogonal conjugation strategies particularly in click chemistry applications The azide moiety allows it to participate in copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO- or BCN-functionalized compounds These properties enable its use in the synthesis of antibody-drug conjugates (ADCs) and in preparing diverse bioconjugates for biomedical research
Apexbio Technology LLC Azido-PEG6-alcohol 86770-69-6 5g
Azido-PEG6-alcohol (CAS 86770-69-6) is a polyethylene glycol-based compound featuring an azide functional group It serves as a versatile building block in bioorthogonal conjugation strategies particularly in click chemistry applications The azide moiety allows it to participate in copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO- or BCN-functionalized compounds These properties enable its use in the synthesis of antibody-drug conjugates (ADCs) and in preparing diverse bioconjugates for biomedical research
Apexbio Technology LLC Azido-PEG6-alcohol 86770-69-6 1g
Azido-PEG6-alcohol (CAS 86770-69-6) is a polyethylene glycol-based compound featuring an azide functional group It serves as a versatile building block in bioorthogonal conjugation strategies particularly in click chemistry applications The azide moiety allows it to participate in copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO- or BCN-functionalized compounds These properties enable its use in the synthesis of antibody-drug conjugates (ADCs) and in preparing diverse bioconjugates for biomedical research
Apexbio Technology LLC Azido-PEG6-alcohol 86770-69-6 500mg
Azido-PEG6-alcohol (CAS 86770-69-6) is a polyethylene glycol-based compound featuring an azide functional group It serves as a versatile building block in bioorthogonal conjugation strategies particularly in click chemistry applications The azide moiety allows it to participate in copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO- or BCN-functionalized compounds These properties enable its use in the synthesis of antibody-drug conjugates (ADCs) and in preparing diverse bioconjugates for biomedical research
Medchemexpress LLC Ladostigil hydrochloride | 209394-18-3 | 99.9% | 308.80 g·mol⁻¹ | C16H21ClN2O2 | 10 MG
Ladostigil hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase, exhibiting neuroprotective, antioxidant, and anti-inflammatory activities. It is used in research on depression and neurodegenerative disorders, and its hydrochloride salt includes an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition for click-chemistry applications.
- Dual inhibitor of cholinesterase and monoamine oxidase.
- Neuroprotective, antioxidant, and anti-inflammatory activities.
- Suitable for research on depression and neurodegeneration.
- Contains an alkyne group for click-chemistry conjugation.
- Provided with analytical documentation such as data sheet and COA.
Medchemexpress LLC JH295 50mg | 1311143-71-1 | 50 MG
JH295 is an irreversible, cysteine-targeted inhibitor of NIMA-related kinase 2 (Nek2) used for biochemical and cellular studies. It irreversibly alkylates Cys22, shows an IC50 of approximately 770 nM, and contains an alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Irreversible Nek2 inhibitor; IC50 ≈ 770 nM.
- Cysteine-targeted covalent mechanism (alkylation of Cys22).
- Contains an alkyne handle for click chemistry applications.
- Molecular weight 320.35; formula C18H16N4O2.
- High reported purity (98.66%).
- Solid, yellow to orange appearance.
Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | MFCD00052012 | 99.9% | 308.63 g/mol | C13H16Cl3NO | 5 MG
Clorgyline hydrochloride is an irreversible, selective monoamine oxidase A (MAO-A) inhibitor used in biochemical and pharmacological research. Supplied as the hydrochloride salt with high reported purity, it is used to probe MAO-A activity, neurotransmitter metabolism, and related signaling pathways. The molecule's alkyne functionality also enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) applications.
- Selective irreversible MAO-A inhibitor.
- High purity suitable for research applications.
- Available in small, precise quantities for laboratory use.
- Contains an alkyne group compatible with CuAAC click chemistry.
- Useful for studies of neurotransmitter metabolism and MAO-A function.
Medchemexpress LLC JH295 10mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 10 MG
JH295 is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor with a reported IC50 of approximately 770 nM. The compound alkylates a cysteine residue (Cys22) in Nek2 and contains an alkyne functional group that enables copper-catalyzed azide-alkyne cycloaddition for bioconjugation. It is supplied as a research reagent for biochemical assays, cellular target validation, and chemical biology applications.
- Irreversible Nek2 inhibition via cysteine alkylation.
- Reported IC50 approximately 770 nM.
- Contains an alkyne for click-chemistry conjugation (CuAAC).
- High reported purity (~98.7%).
- Suitable for biochemical assays and chemical biology applications.
Medchemexpress LLC Azido-PEG6-alcohol | 86770-69-6 | MFCD22056309 | 98.0% | 307.34 g/mol | C12H25N3O6 | 5 G
Azido-PEG6-alcohol is an azide-terminated polyethylene glycol (PEG6) linker reagent supplied as a 5 g reagent for use in click chemistry and conjugation workflows. It contains a terminal azide and a terminal hydroxyl group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Azide-terminated PEG6 linker suitable for conjugation chemistry.
- Terminal hydroxyl group enables further functionalization.
- Compatible with CuAAC and SPAAC click reactions.
- Purity 98.0%.
- Colorless to light yellow liquid.
- Recommended storage: pure form -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC JH295 5mg | 1311143-71-1 | 320.35 g/mol | C18H16N4O2 | 5 MG
JH295 is a potent, irreversible, and selective NIMA-related kinase 2 (Nek2) inhibitor that contains an alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry). Supplied as a 5 mg quantity at 98.66% purity, the compound has a molecular weight of 320.35 g/mol and formula C18H16N4O2; reported cellular IC50 for Nek2 is 770 nM and the mechanism involves covalent alkylation of Cys22.
- Irreversible Nek2 inhibitor with reported IC50 of 770 nM.
- Contains an alkyne group for CuAAc click chemistry.
- Mechanism involves covalent alkylation of cysteine residue Cys22.
- Supplied as a 5 mg quantity at 98.66% purity.
- Molecular weight 320.35 g/mol; chemical formula C18H16N4O2.
Medchemexpress LLC tert-butyl N-(4-azidobutyl)carbamate | 129392-85-4 | MFCD24452574 | ≥98.0% | 214.26 | C9H18N4O2 | 5 G
tert-Butyl N-(4-azidobutyl)carbamate is an N-Boc-protected azidobutyl carbamate used as a bifunctional crosslinker and synthetic building block for chemical biology and organic synthesis. The azide moiety enables bioorthogonal conjugation via azide-alkyne cycloaddition, and the Boc protecting group can be removed under mild acidic conditions to expose a free amine for further derivatization.
- Enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition for stable triazole formation.
- Boc protection provides orthogonal protection and straightforward acid-mediated deprotection.
- Suitable as a bifunctional crosslinker and building block for bioconjugation workflows.
- Molecular formula C9H18N4O2; molecular weight 214.26 g/mol for reference.