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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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ABT-418 hydrochloride is a potent, selective agonist of neuronal nicotinic acetylcholine receptors (nAChRs) used in preclinical research to investigate cholinergic signaling, cognition, and anxiolytic mechanisms. It is supplied as a solid and as a ready-to-use 10 mM solution for laboratory applications. CAS 147388-83-8; molecular weight 202.68 g·mol⁻¹. For research use only.
Potent, selective agonist of neuronal nicotinic acetylcholine receptors.
Available as solid and as 10 mM solution ready for use.
High purity suitable for analytical and biological studies.
Stable under recommended storage conditions.
Intended for laboratory research use only.
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Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent selective ATP-competitive and orally active CDK7 inhibitor with an IC50 of 41 nM Samuraciclib hydrochloride displays 45- 15- 230- and 30-fold selectivity over CDK1 CDK2 (IC50 of 578 nM) CDK5 and CDK9 respectively Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0 2-0 3 M Samuraciclib hydrochloride has anti-tumor effects[1 [2
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(E E)-Farnesol (trans trans-Farnesol) is a quorum-sensing molecule of Candida species (E E)-Farnesol can inhibit the growth metabolism and biofilm formation of various Candida species and affect their morphology and invasiveness[1]
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Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor) is a type I transmembrane protein that can regulate several signaling pathways Within the cell IL-17RD expression has been localized mainly to the plasma membrane IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling[1] IL-17RD Protein Mouse (CHO) is produced in CHO cells and consists of 2713 amino acids (G29-R299)
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Quinagolide hydrochloride is the hydrochloride salt of quinagolide, a non-ergot-derived selective dopamine D2 receptor agonist used in research on prolactin regulation and dopaminergic signaling. Supplied as a research-grade solid with high purity for reliable in vitro and in vivo pharmacology studies.
Selective dopamine D2 receptor agonist for prolactin research.
Hydrochloride salt improves aqueous solubility.
High purity (≈99.7%) for reproducible results.
Suitable for in vitro and in vivo pharmacology studies.
Available in research-scale pack sizes for dose-ranging experiments.
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hsa-miR-21-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA antagomirs have 2 phosphorothioates at the 5 end 4 phosphorothioates at the 3 end 1 cholesterol group at the 3 end and full-length nucleotide 2 -methoxy modification The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors they exhibits enhanced cellular uptake stability and regulatory activity in vivo
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