Phenols
Alkali Scientific Thymine, 25 G
Thymine is a nucleobase essential for DNA structure, acting as one of the building blocks of genetic material. This chemical is widely used in laboratory applications involving nucleic acid synthesis and analysis. Thymine, a pyrimidine base, pairs specifically with adenine in double-stranded DNA through hydrogen bonds, playing a critical role in the genetic code’s integrity. It is used in biochemical research, including studies on DNA replication, repair, and transcription. The 25g format is convenient for laboratory-scale experiments, including DNA synthesis, sequencing, and various enzymatic reactions. Thymine is commonly utilized in the production of synthetic oligonucleotides and other biochemical reagents.
Medchemexpress LLC BDNF Human CHO 10ug
Recombinant human brain-derived neurotrophic factor (BDNF), expressed in CHO cells and supplied lyophilized for research use. The material corresponds to residues H129-R247, is >95% pure by reducing SDS-PAGE, and is formulated from 0.22 μm filtered PBS. It is intended for in vitro studies of neuronal survival, differentiation, and receptor signaling; store lyophilized at -20°C and aliquot for long-term storage at -80°C.
- Expressed in CHO cells for mammalian post-translational modifications.
- Covers residues H129-R247 relevant to receptor binding.
- Purity greater than 95% by reducing SDS-PAGE.
- Lyophilized from a 0.22 μm filtered PBS solution for stability.
- Suitable for in vitro studies of neuronal survival, differentiation, and signaling.
- Stable when frozen; aliquot and store at -20°C or -80°C for extended storage.
Medchemexpress LLC 5-Bromo-3-methylpyridin-2-ol | 89488-30-2 | 99.7% | C6H6BrNO | 10 G
5-Bromo-3-methylpyridin-2(1H)-one is a biochemical reagent intended for life science research. This compound appears as a white to off-white solid with a molecular weight of 188.02 and a chemical formula of C6H6BrNO.
- High purity for research applications
- Biochemical reagent for life science research
- White to off-white solid appearance
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Sodium benzenesulfinate | 873-55-2 | 99.9% | 164.16 | 500 G
Sodium benzenesulfinate is a reagent used in organic synthesis to create other compounds, such as sulfones. It undergoes rhodium-catalyzed desulfinative coupling with aldehydes to yield ketones. This product is a solid, white to off-white in appearance.
- Used in organic synthesis
- Undergoes rhodium-catalyzed desulfinative coupling
- Available as a solid
- White to off-white color
- Stable under recommended storage conditions
- Incompatible with strong acids/alkalis, strong oxidizing/reducing agents
eMolecules 128-09-6 | N-Chlorosuccinimide | Chem-Impex | MFCD00005511 | 133.530 | C4H4ClNO2 | 99.000 | ClN1C(=O)CCC1=O | 1kg | 112760463
N-Chlorosuccinimide | Chem-Impex | 128-09-6 | MFCD00005511 | 133.530 | C4H4ClNO2 | 99.000 | ClN1C(=O)CCC1=O | 1kg | 112760463
Apexbio Technology LLC AS-605240 648450-29-7 10mM (in 1mL DMSO)
AS-605240 (CAS 648450-29-7) is a cell-permeable small molecule inhibitor selectively targeting class I phosphoinositide 3-kinases (PI3Ks) with pronounced potency against the PI3K isoform (IC50 0 008 M) and lower activity for PI3K / / (IC50 0 06 0 27 and 0 3 M respectively) Structural studies show that AS-605240 binds to PI3K via interactions with Lys-833 and Val-882 It impairs PI3K/Akt signaling as evidenced by inhibition of C5a-induced PKB phosphorylation in RAW264 macrophages In vivo AS-605240 reduces leukocyte migration and suppresses joint inflammation in mouse models of peritonitis and collagen-induced arthritis highlighting its value for investigating PI3K -mediated immune pathways and inflammatory processes
Medchemexpress LLC N-hydroxyisonicotinamidine | 1594-57-6 | MFCD00125873 | ≥95.0% | 137.14 g/mol | C6H7N3O | 25 G
N-Hydroxyisonicotinamidine is an amidoxime-based chemical intermediate supplied as a powder for research use. It functions as a collector and a building block in organic synthesis, notably in the preparation of substituted α-1,2,4-oxadiazole esters. The compound has formula C6H7N3O and a molar mass of 137.14 g/mol, and is soluble in DMSO at high concentrations.
Medchemexpress LLC Hydrochlorothiazide impurity C | 402824-96-8 | 1mg
HCTZ-CH2-HCTZ is an isomer of HCTZ (HY-B0252) Hydrochlorothiazide (HCTZ) an orally active diuretic agent of the thiazide class inhibits transforming TGF- /Smad signaling pathway[1][2]
Medchemexpress LLC Oxaceprol | 33996-33-7 | 99.7% | 173.17 | 25 G
Oxaceprol is an orally active derivative of L-proline, possessing distinct anti-inflammatory activity. It is primarily used for research on osteoarthritis and rheumatoid arthritis. Oxaceprol has been shown to significantly reduce the surface area and wet weight of cotton pellet granulomas in vivo, and to inhibit secondary lesions in the ears and tail in animal models. It does not inhibit prostaglandin synthesis in vitro but markedly inhibits neutrophil infiltration into the joints of rats with adjuvant arthritis.
- Orally active derivative of L-proline
- Possesses anti-inflammatory activity
- Used for research on osteoarthritis and rheumatoid arthritis
- Reduces cotton pellet granulomas in vivo
- Inhibits secondary lesions in animal models
- Does not inhibit prostaglandin synthesis in vitro
- Markedly inhibits neutrophil infiltration into joints
Medchemexpress LLC NA/Neuraminidase In 300U
Neuraminidase (NA) is described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors Whereby NA facilitates viral invasion of the upper airways facilitates virus release during virus budding prevents self-aggregation and ensures the efficient spread of the progeny virus from cell to cell and also plays a role in the determination of host range restriction on replication and virulence NA/Neuraminidase Protein Influenza A H5N1 (H255Y HEK293) is the recombinant Virus-derived NA/Neuraminidase protein expressed by HEK293 with tag free and H255Y mutation It originates from cell lysates collected after expressing a DNA sequence encoding the Influenza A virus neuraminidase
Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 1 ML
JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It demonstrates potent inhibition of various EML4-ALK mutants and exhibits selectivity against other kinases. This compound shows inhibitory growth in several cancer cell lines and possesses good oral bioavailability, with the ability to penetrate the CNS in mice.
- Potently inhibits EML4-ALK G1202R, EML4-ALKwt, and other EML4-ALK mutants
- Demonstrates selectivity against IRAK1, CLK4, RET, and IRAK4
- Exhibits inhibitory growth in H3122 and DFCI76 cancer cell lines
- Good oral bioavailability in mice
- Penetrates the central nervous system in mice
Medchemexpress LLC N-hydroxysulfosuccinimide (sodium) | 106627-54-7 | MFCD00043100 | 100.0% | 217.13 g/mol | C4H4NNaO6S | 100 G
N-hydroxysulfosuccinimide (sodium) is the sodium salt of sulfo-N-hydroxysuccinimide, supplied as a white to off-white solid. It serves as a water-soluble activated ester reagent for preparing amine-reactive sulfo-NHS esters for protein modification and bioconjugation, and is used as a non-cleavable linker in antibody-drug conjugate synthesis. Store sealed and protected from moisture.
- Water-soluble activated ester for efficient amine coupling.
- Suitable for protein modification and bioconjugation.
- Used as a non-cleavable linker in antibody-drug conjugate synthesis.
- High purity (99.99%).
- White to off-white solid, stable when stored sealed and dry at 4°C.
- Molecular weight 217.13 g/mol; formula C4H4NNaO6S.
- Available in solid pack sizes up to 100 g.
Medchemexpress LLC 2-Pyridinecarboxamide | 1452-77-3 | 100.0% | 122.13 g/mol | C6H6N2O | 25 G
Picolinamide is a small-molecule research chemical reported to inhibit poly(ADP-ribose) synthetase (PARS) in nuclei from rat pancreatic islet cells. It is supplied as a high-purity solid intended for laboratory research; consult the safety data sheet for handling and storage.
- Inhibitor of poly(ADP-ribose) synthetase in reported studies.
- High purity suitable for research assays.
- Available in multiple pack sizes for laboratory use.
- Solid form with a molecular weight of 122.13 g/mol.
- CAS number 1452-77-3 for unambiguous identification.
Medchemexpress LLC 2'-bromo-2'-deoxyuridine | 4753-02-0 | MFCD06658226 | 96.9% | 307.10 | C9H11BrN2O5 | 1 ML
2'-Bromo-2'-deoxyuridine is a brominated deoxyuridine nucleoside analog used in research to label DNA and investigate DNA synthesis, cell proliferation, and apoptosis. It is supplied both as a ready-to-use 10 mM solution (1 mL) and as solid quantities for synthesis and assay use.
- Brominated deoxyuridine nucleoside analog for DNA labeling and tracking.
- Supplied as a 10 mM solution in 1 mL and in solid pack sizes for flexibility.
- High purity (~96.9%) suitable for cellular and biochemical assays.
- Commonly used to measure DNA synthesis and cell proliferation in vitro.
- Compatible with standard handling and storage practices for nucleoside reagents.
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eMolecules 3240-34-4 | (Diacetoxyiodo)benzene | Chem-Impex | MFCD00008692 | 322.098 | C10H11IO4 | 99.000 | CC(=O)O[I](OC(C)=O)c1ccccc1 | 1kg | 112760628
(Diacetoxyiodo)benzene | Chem-Impex | 3240-34-4 | MFCD00008692 | 322.098 | C10H11IO4 | 99.000 | CC(=O)O[I](OC(C)=O)c1ccccc1 | 1kg | 112760628