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Filtered Search Results
![Medchemexpress LLC 3-(4-methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone | 346640-08-2 | 98.0% | 378.45 | C15H10N2O4S3 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 3-(4-methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone | 346640-08-2 | 98.0% | 378.45 | C15H10N2O4S3 | 25 MG
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CCF642 is a small-molecule protein disulfide isomerase (PDI) inhibitor reported to have an IC50 of 2.9 μM and to induce endoplasmic reticulum stress and apoptosis in multiple myeloma cells. The compound is supplied for research use with documented solubility and storage guidance for experimental workflows.
- Potent PDI inhibition with reported IC50 of 2.9 μM.
- Induces ER stress and apoptosis in multiple myeloma models.
- High solubility in DMSO for in vitro stock preparation.
- Stable as a powder under recommended cold storage conditions.
- Documented in vitro and in vivo formulation guidance for experimental use.
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Medchemexpress LLC Trifarotene | 895542-09-3 | 99.1% | 459.58 g/mol | C29H33NO4 | 100 MG
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Trifarotene is a selective retinoic acid receptor γ (RARγ) agonist supplied as a white to off-white solid for research use. It is intended for in vitro and in vivo studies of RAR/RXR signaling and related pathways and is not for human therapeutic use.
- High purity (≈99.1% by LCMS)
- Chemical formula C29H33NO4, molecular weight 459.58 g/mol
- Soluble in DMSO (≈250 mg/mL) and formulatable for in vivo dosing
- Stable under recommended powder and solution storage conditions
- Suitable for receptor pharmacology and preclinical studies
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Medchemexpress LLC PRMT5-IN-1 hydrochloride | 99.5% | 455.29 | 10 MG
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PRMT5 IN-1 hydrochloride (compound 9), a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. It can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions. It is for research use only and not sold to patients.
- Potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor
- IC50 of 11 nM for PRMT5/MEP50
- Inhibits the PRMT5/MEP50 complex very rapidly with a Kinact of 0.068 min-1 and a good binding affinity (KI=55 nM)
- Inhibits the expression of cellular sDMA with an IC50 value of 0.012 μM in Granta-519 cells
- Inhibits cell proliferation in a dose-dependent manner with an IC50 value of 0.06 μM in Granta-519 cells
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Selleck Chemical LLC K-Ras
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K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C)
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eMolecules Medchem Express / JW 642 / 10mg / 415686836 / HY-12332 / / 1416133-89-5 / MFCD22987956 / 462.392 / C21H20F6N2O3
Medchem Express / JW 642 / 10mg / 415686836 / HY-12332 / / 1416133-89-5 / MFCD22987956 / 462.392 / C21H20F6N2O3
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eMolecules 2-Benzylaminopropanol | 3217-09-2 | MFCD00021997 | 100mg
Apollo Scientific | 2-Benzylaminopropanol | 100mg | 562465426 | OR510057 | 97.000 | 3217-09-2 | MFCD00021997 | 165.236 | C10H15NO
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Matrix Scientific 4-ISOPROPOXYANILINE-5G
4-Isopropoxyaniline, 5g,C9H13NO, MFCD00059188, mw 151.21, [7664-66-6]
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383275 BO-264 50MG
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eMolecules N-Nitroso(2-hydroxyethyl)glycine | 80556-89-4 | MFCD01724687 | 100mg
Toronto Research Chemicals | N-Nitroso(2-hydroxyethyl)glycine | 100mg | 483427237 | N528400 | | 80556-89-4 | MFCD01724687 | 148.118 | C4H8N2O4
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Medchemexpress LLC Acebilustat | 943764-99-6 | 99.7% | 481.54 | 100 MG
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Acebilustat is a leukotriene A4 hydrolase inhibitor, used as an oral antiinflammatory agent. It is safe and well tolerated in phase 1 trials. This antiinflammatory drug is in development for the treatment of CF and other diseases, acting as a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a powerful chemoattractant and activator of inflammatory immune cells like neutrophils.
- Leukotriene A4 hydrolase inhibitor
- Oral antiinflammatory agent
- Safe and well tolerated in phase 1 trials
- Potent inhibitor of LTA4H
- Inhibits the formation of leukotriene B4 (LTB4)
- Being developed for the treatment of cystic fibrosis (CF) and other diseases
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Medchemexpress LLC Di((Z)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate | 1351586-50-9 | 98.0% | 678.04 g·mol⁻¹ | C41H75NO6 | 5 MG
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L319 is an ionizable cationic lipidoid (Di((Z)-non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) used to formulate synthetic liposomes and lipid nanoparticles. The material is provided at research-grade purity and is intended for formulation and delivery studies in preclinical research.
- Ionizable cationic structure suitable for pH-dependent delivery.
- High supplied purity (98.0%) for reproducible formulation.
- Applicable to synthetic liposome and lipid nanoparticle assembly.
- Well-characterized molecular properties facilitate formulation optimization.
- Available in small research quantities for screening and development.
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Medchemexpress LLC HY-16901 10mg Medchemexpress, Firsocostat CAS:1434635-54-7 Purity:>98%
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Medchemexpress, HY-16901 10mg Firsocostat CAS:1434635-54-7 Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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MEDCHEMEXPRESS LLC MARDEPODECT HYDROCHLORIDE 5M
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501873850 MARDEPODECT HYDROCHLORIDE 5M
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MEDCHEMEXPRESS LLC GPR120 MODULATOR 2 5MG
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501873856 GPR120 MODULATOR 2 5MG
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MEDCHEMEXPRESS LLC MERTANSINE 5MG
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501873770 MERTANSINE 5MG
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