BioCore SEC is a family of high performance, size exclusion chromatography columns designed for separating a broad range of biomolecules based on size. This column technology involves the creation of a neutral hydrophilic layer on the surface of specially designed, high-strength, monodispersed silica particles, combined with well-established column packing processes. BioCore SEC-120 columns are suited for aggregate determination of peptides, small proteins and related substances.