HPLC Columns
Waters Corp WATERS CORPORATION Oasis MCX Online Column, 80 Å, 30 μm, 3.9 mm X 20 mm
The Oasis MCX on-line column is engineered for robust, reproducible, and ultrafast on-line Solid Phase Extraction (SPE). It incorporates a unique mixed-mode polymeric sorbent designed for enhanced selectivity and sensitivity in extracting basic compounds with cation-exchange groups. This column features traditional HPLC column fittings and hardware.
- Filling material: MCX
- Separation mode: Mixed-mode
- Particle matrix: Copolymer
- pH range: 0 pH to 14 pH
- Endcapped: No
- Particle shape: Spherical
- Particle size: 30 μm
- Pore size: 80 Å
- Format: Online column
- Inner diameter: 3.9 mm
- Ion exchange capacity: 1 meq/gram
- Length: 20 mm
- Units per package: 1 pk
Waters Corp Waters BioSuite C18 Column, 500Å, 7 μm, 2 mm × 150 mm
The BioSuite C18 Column primarily supports legacy methods, featuring large pore size and high chemical stability. Its 500 Å pore size pC18 base matrix accommodates proteins up to 2,500,000 Daltons, providing greater protein or peptide binding capacity than nonporous chemistries.
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Polymethacrylate
- PH range: 2 to 12 pH
- Maximum pressure: 6000 psi (415 Bar)
- Endcapped: Yes
- Molecular weight range: 1,000 to 30,000
- Particle shape: Spherical
- Particle size: 7 μm
- Endfitting type: Parker-style
- Pore size: 500 Å
- Format: Column
- System: HPLC
- USP classification: L1
- Inner diameter: 2 mm
- Length: 150 mm
- Application: Peptide
- Units per package: 1 per package
Waters Corp Waters BioSuite C18 Column, 500Å, 13 μm, 21.5 mm × 150 mm
The BioSuite C18 Column supports legacy methods, offering a large pore size and high chemical stability. Its pC18 and pPhenyl resin-based packings are bonded to a pH stable, methacrylic ester-based polymeric resin. The 500 Å pore size accommodates proteins up to 2,500,000 Daltons. These columns provide superior chromatographic resolution, suitable for both “lab scale” isolations and narrow-bore HPLC/LC-MS applications.
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Polymethacrylate
- pH range: 2 pH to 12 pH
- Maximum pressure: 6000 psi (415 Bar)
- Particle size: 13 μm
- Pore size: 500 Å
- Inner diameter: 21.5 mm
- Length: 150 mm
- Application: Peptide
Waters Corp Symmetry C8 Intelligent Speed (IS) Column, 100Å, 3.5 µm, 3.9 mm X 20 mm, 1/pk
Symmetry C8 columns feature monofunctionally bonded C8 ligands on a high purity base-deactived silica. Symmetry columns have the tightest column specifications in the industry giving resulting highly reproducible chromatographic results.
Waters Corp BioSuite DEAE Anion-Exchange Column 1000Å 10 µm, 7.5mm x 75 mm, 1/pk
Waters BioSuite ion-exchange column offerings include strong and weak, cation (CXC) and anion-exchangers (AXC) bonded to a pH stable (i.e., pH 2 -12), methacrylic ester-based polymeric resin. The availability of four separation chemistries provides chromatographers with the flexibility required to develop methods that separate proteins and / or peptides based upon minor charge differences. Nonporous (NP) and porous IEX columns are also available. Superior chromatographic resolution is possible using the nonporous IEX offerings however, greater binding capacity is obtained with the porous selections. In addition, selected BioSuite ion-exchange columns are available in PEEK hardware as well as in 21.5 mm preparative column sizes.
Waters Corp Oasis Online Column, 80Å, 30 μm, 3.9 mm X 20 mm
The Oasis MAX on-line column is engineered for rugged, reproducible, and ultra-fast on-line Solid Phase Extraction (SPE). It incorporates the Oasis MAX sorbent, a water-wettable, mixed-mode polymeric sorbent optimized for higher selectivity and sensitivity in extracting acidic compounds in anion-exchange groups.
- Engineered for rugged, reproducible, and ultra-fast on-line Solid Phase Extraction (SPE).
- Contains a water-wettable, mixed-mode polymeric sorbent.
- Optimized for higher selectivity and sensitivity in extracting acidic compounds with anion-exchange groups.
- Designed for use with appropriate narrow-bore analytical columns.
- Cartridge column features traditional HPLC column fittings and hardware.
Waters Corp Waters BioSuite Diol (OH) Column, 13 μm, 450 Å, 7.5 mm X 300 mm
This Diol (OH) Column primarily supports legacy methods and is designed for Size Exclusion Chromatography (SEC) applications. It is available in various inner diameters for analytical and preparative separations.
- Chemistry: Diol (OH)
- Separation mode: SEC
- Particle substrate: Silica
- pH range: 2.5 to 7.5
- Maximum pressure: 15 bar (225 psi)
- Particle size: 13 μm
- Pore size: 450 Å
- Inner diameter: 7.5 mm
- Length: 300 mm
- USP classification: L59
- Molecular weight range: 20,000 to 1,000,000
- System: HPLC
- Application: Protein
Waters Corp Waters HPLC Column, Shield RP18, 5 μm, 50 x 100 mm
XTerra HPLC Columns, featuring Hybrid Particle Technology (HPT), merge silica and polymer benefits for enhanced speed, resolution, and pH 1–12 stability. These robust, efficient columns support analytical and preparative chromatography with direct scale–up, particularly for basic compounds.
- Wide pH range (1–12) for robust separations.
- HPT delivers high efficiency and sharp peaks for basic compounds.
- High strength and chemical stability extend column lifetime, especially at high pH (>8.0).
- Shield technology improves basic analyte peak shape.
- OBD design enables direct scale–up.
- Versatile C18, C8, and Phenyl chemistries.
- MS compatibility: sharp peaks, high sensitivity.
- eCord/eConnect tags provide traceability and usage data.
Waters Corp HPLC Column, 5.0 μm Particle, 100 Å Pore, 4.6 × 20 mm
These reversed-phase columns utilize patented embedded polar group technology, which “shields” the residual silanol surface of the silica from highly basic analytes. The reduced silanol activity of the RP18 column significantly enhances peak shape and resolution.
- Contains patented embedded polar group technology.
- Shields the silica’s residual silanol surface from highly basic analytes.
- Reduced silanol activity.
- Significantly improves peak shape and resolution.
Waters Corp Waters Preparative Column, C18, 5 μm, 50 mm ID, 100 mm Length
XTerra Prep columns incorporate Hybrid Particle Technology for isolation and purification in discovery and development laboratories. XTerra Prep MS columns feature patented Hybrid Particle Technology, with particles specifically engineered for preparative applications. This technology allows for operation at pH 1–12, enabling up to 60X more loading capacity onto the column. This increased capacity results in fewer injections to obtain the same amount of pure material or more material with the same number of injections. For discovery applications, this greater capacity allows for the use of a shorter column, producing the same amount of material in half the time.
- Patented Hybrid Particle Technology.
- Operates routinely at pH 1–12.
- Load up to 60X more onto the column.
- Allows for use of shorter columns to achieve the same material in half the time in discovery.
Waters Corp Waters Column, Phenyl, 13 μm, 1000 Å, 21.5 mm × 150 mm
These columns separate proteins and peptides based on their hydrophobic characteristics, offering an alternative to reversed-phase chromatography when proteins may denature at high organic solvent concentrations. Hydrophobic Interaction Chromatography (HIC) uses adsorption to a weakly hydrophobic surface at high salt concentrations, followed by elution with a decreasing salt gradient. This combines non-denaturing properties with HPLC precision for effective separation. A large 1000 Å pore size accommodates proteins up to 5,000,000 Daltons.
- Endcapped design.
- Parker-style endfitting type.
- Enables non-denaturing separation of biomolecules, preserving biological activity.
- Accommodates large proteins up to 5,000,000 Daltons due to a 1000 Å pore size.
- Polymeric resin provides pH stability for method development.
Waters Corp XTerra MS C8 OBD Prep Column, 125Å, 10 µm, 19 mm X 150 mm, 1/pk
XTerra Prep columns bring the benefits of Hybrid Particle Technology to isolation and purification applications in discovery and development laboratories. XTerra Prep MS columns possess our patented Hybrid Particle Technology, with particles engineered specifically for prep. It allows you to routinely operate at pH 1-12 so you can load up to 60X more onto the column. More capacity results in fewer injections for the same amount of pure material or more material with the same number of injections. In the discovery world, this greater capacity means you can use a shorter column, producing the same amount of material in half the time.
Waters Corp XTerra MS C18 OBD Prep Column, 125Å, 10 µm, 19 mm X 150 mm, 1/pk
XTerra Prep columns bring the benefits of Hybrid Particle Technology to isolation and purification applications in discovery and development laboratories. XTerra Prep MS columns possess our patented Hybrid Particle Technology, with particles engineered specifically for prep. It allows you to routinely operate at pH 1-12 so you can load up to 60X more onto the column. More capacity results in fewer injections for the same amount of pure material or more material with the same number of injections. In the discovery world, this greater capacity means you can use a shorter column, producing the same amount of material in half the time.
Waters Corporation BioSuite Q Anion-Exchange Column, 13 μm, 21.5 mm x 150 mm, Polymer
This BioSuite Q Anion-Exchange Column is designed for protein and peptide separations, offering excellent resolution and recovery. It is scalable from analytical to lab-scale preparative applications. With a 21.5 mm diameter, this column is suitable for preparative applications. The methacrylic ester-based polymeric resin provides pH stability from pH 2–12.
- Designed for protein and peptide separations
- Offers excellent resolution and recovery of proteins and peptides
- Scalable from analytical to lab-scale preparative applications
- Suitable for preparative applications due to 21.5 mm diameter
- Methacrylic ester-based polymeric resin provides pH stability from pH 2–12
- Strong-anion exchanger
- Particle size: 13 μm
- Dimensions: 21.5 mm x 150 mm
Waters Corp Waters μBondapak Prep Column, C18, 10 μm, 30 mm X 300 mm
μBondapak C18 columns are general-purpose, silica-based, reversed-phase C18 columns that are based on 10 μm particle technology. They offer a balance between resolution, throughput, and cost for preparative chromatography.
- General-purpose, silica-based, reversed-phase C18 columns
- Based on 10 μm particle technology
- Offers a balance between resolution, throughput, and cost for preparative chromatography
- Chemistry: C18
- Separation mode: Reversed phase
- Particle substrate: Silica
- pH range: 2 to 8 pH
- Temperature limits: 45 °C
- Maximum pressure: 6000 psi (415 Bar)
- Endcapped: Yes
- Silanol activity: High
- Particle shape: Irregular
- Pore size: 125 Å
- Inner diameter: 30 mm
- Length: 300 mm
- Carbon load: 10%
- Units per package: 1 pk