Enzymes and Inhibitors
Medchemexpress LLC Ac-YEVD-AMC | 1631716-11-4 | 99.6% | 723.73 | 5 MG
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11 that releases amino-4-methylcoumarin (AMC) for fluorescence detection when treated with cell lysate. This product is for research use only.
- Fluorescent substrate of caspase-1/11
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- For research use only
Medchemexpress LLC Ac-IETD-AFC | 211990-57-7 | 99.3% | 729.65 | 10 MG
Ac-IETD-AFC is a fluorogenic substrate for caspases-8, -3, and -10, as well as granzyme B. This product is intended for research use only and is not sold to patients.
- Fluorogenic substrate for caspase-8, caspase-3, caspase-10, and granzyme B
- Suitable for enzyme labeling and fluorescence studies
- Used in apoptosis and caspase research
- Excitation wavelength less than 380 nm
- Emission wavelength 496-570 nm (green)
Medchemexpress LLC 6′-amino-D-luciferin | 161055-47-6 | MFCD29912852 | ≥95.0% | 279.34 g/mol | C11H9N3O2S2 | 5 MG
6′-Amino-D-luciferin is a derivative of D-luciferin with the 6-position hydroxyl replaced by an amino group. It acts as a luciferase substrate for bioluminescence assays and is commonly used for IVIS imaging in cell and animal studies. The compound is supplied as a solid with defined storage recommendations and standard analytical characterization for laboratory use.
- Natural substrate for luciferase enabling bioluminescent assays.
- Suitable for IVIS imaging in cell and animal experiments.
- Solid, light yellow to brown appearance for easy handling.
- Stable under recommended cold storage conditions for long-term use.
- Molecular weight 279.34 g/mol and CAS 161055-47-6 for identification.
Medchemexpress LLC Z-Gly-Gly-Arg-AMC | 66216-78-2 | 99.9% | 579.60 | 50 MG
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate used for testing thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm).
- Thrombin-specific fluorogenic substrate.
- Suitable for testing thrombin generation in PRP and platelet-poor plasma (PPP).
- Excitation/Emission wavelengths: 390/480 nm.
Medchemexpress LLC N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin | 169332-61-0 | 99.2% | 675.64 | 25 MG
Ac-DEVD-AMC is a fluorescent substrate for caspase-3 and caspase-7. Upon treatment with cell lysate, it facilitates the release of amino-4-methylcoumarin (AMC), which allows for fluorescence detection at an excitation wavelength of 380 nm and an emission wavelength of 460 nm.
- Fluorescent substrate of caspase-3/caspase-7
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- Excitation wavelength of 380 nm
- Emission wavelength of 460 nm
Medchemexpress LLC Her2/CD340 protein, rat (HEK293, His) | >95.0% | 5 UG
Recombinant rat HER2/CD340 protein expressed in HEK293 cells with a C-terminal His tag. Supplied as a purified ectodomain suitable for biochemical assays, antibody development, receptor binding studies, and structural or biophysical analysis. Molecular weight is approximately 91 kDa and purity is greater than 95% by reducing SDS-PAGE.
- Recombinant rat HER2 protein produced in HEK293 expression system.
- C-terminal His tag for efficient purification.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Approximate molecular weight 91 kDa.
- Suitable for biochemical assays, antibody generation, and binding studies.
- Available in small research quantities (for example, 5 μg).
American Research Products Inc General SPH ELISA Kit
This General Sphingosine (SPH) ELISA Kit is a precoated Competitive Inhibition ELISA assay designed to detect and quantify the target analyte in tissue homogenates cell lysates and other biological fluids This product is for Research Use Only
Medchemexpress LLC Ac-IETD-AFC | 211990-57-7 | 99.28% | 729.65 | 5 MG
Ac-IETD-AFC is a fluorogenic substrate for caspase-8, caspase-3, caspase-10, and granzyme B. It is intended for research use only.
- Fluorogenic substrate
- Substrate for caspase-8, caspase-3, caspase-10
- Substrate for granzyme B
- Not intended for human use
Medchemexpress LLC Z-Gly-Pro-AMC | 68542-93-8 | 99.8% | 463.48 g/mol | C25H25N3O6 | 10 MG
Z-Gly-Pro-AMC is a fluorogenic peptide substrate used to measure prolyl endopeptidase activity. Enzymatic hydrolysis releases the fluorescent 7-amino-4-methylcoumarin (AMC), enabling sensitive fluorometric assays.
- Hydrolyzed by prolyl endopeptidase to release 7-amino-4-methylcoumarin (AMC).
- Excitation 380 nm, emission 465 nm for fluorometric detection.
- High purity: 99.8%.
- Molecular weight 463.48 g/mol; molecular formula C25H25N3O6.
- Available as a 10 mg vial for laboratory assays.
- Suitable for enzymatic activity assays and fluorescence-based screening.
Medchemexpress LLC H-Asp(AMC)-OH | 133628-73-6 | MFCD00236804 | 99.8% | 290.27 g/mol | C14H14N2O5 | 10 MG
H-Asp(AMC)-OH is an aspartic acid derivative linked to 7-amino-4-methylcoumarin (AMC) used as a fluorescent substrate in biochemical and enzymatic assays. It is supplied in small research quantities and characterized for assay use with reported high purity and defined storage recommendations.
- Fluorescent aspartic acid derivative for use as a substrate in assays.
- Does not inhibit glycine transport at a concentration of 0.25 mM.
- High purity (99.75%) suitable for research applications.
- Molecular weight 290.27 g/mol; formula C14H14N2O5.
- Available in a 10 mg pack size for laboratory use.
- Store sealed, away from moisture and light; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC H-Glu(AMC)-OH | 98516-76-8 | MFCD00038085 | 98.0% | 304.30 g/mol | C15H16N2O5 | 50 MG
H-Glu(AMC)-OH is a fluorogenic amino acid derivative used as a peptide substrate to measure aminopeptidase A enzyme activity. Enzymatic cleavage releases 7-amino-4-methylcoumarin (AMC), producing a fluorescent signal that enables quantitative fluorescence-based activity assays. Intended for research use only.
- Fluorogenic substrate for aminopeptidase A activity assays.
- Releases 7-amino-4-methylcoumarin (AMC) upon enzymatic cleavage.
- Enables quantitative fluorescence-based enzyme activity measurements.
- Available as a solid powder suitable for storage and assay preparation.
- Molecular weight 304.30 g/mol; formula C15H16N2O5.
- For research use only; not validated for medical applications.
TOPOGEN INC HMN RECOMB TOPOISOMERASE 250
Recombinant Human Topoisomerase I (overexpressed in baculovirus). 250 units. Storage: -20 C
Medchemexpress LLC Casein Kinase 1 alpha Antibody (YA564) | Affinity purified | Predicted: 39 kDa, Observed: 34 kDa | 10 UL
Casein Kinase 1 alpha Antibody (YA564) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting Casein Kinase 1 alpha. It is for research use only.
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Species reactivity: Human, rat
- Immunogen: Synthetic peptide corresponding to human Casein Kinase 1 alpha. The exact sequence is proprietary to MCE.
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Modification: Unmodified
- Isotype: IgG
- Appearance: Liquid
- Formulation: Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide.
- Storage and stability: Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
- Shipping: Shipping with blue ice.