Custom Peptides
Cayman Chemical Fraxnol 10mg
An Hsp27 and microtubule inhibitor inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner inhibits PKC phosphorylation of Hsp27 induces HCT116 cell cycle arrest in the G2/M phase via formation of the Mad2/p55CDC inhibitory complex and Bax activation of apoptosis inhibits microtubule polymerization in HCT116 cells reduces tumor volume in an HCT116 mouse xenograft model (50-100 mg/kg)
Cayman Chemical Gartnn 10mg
A derivative of sorafenib selectively inhibits proliferation of BEL-7402 MGC803 and T24 bladder cancer cells (IC50s 5 77 5 21 and 3 97 UM respectively) over non-cancerous HCV-29 cells (IC50 23 19 UM) induces apoptosis in T24 cells at 2-6 UM induces ferroptosis in T24 cells at 6 UM when incubated for 10 hours induces autophagy at 6 UM when incubated for 8 hours
Cayman Chemical Pteryxn 10mg
A flavonoid glycoside with diverse biological activities potentiates TRAIL-induced cytotoxicity and apoptosis in U87MG human glioma cells potentiates TRAIL-induced tumor cell apoptosis and reduction of tumor growth in a U87MG mouse xenograft model reduces pulmonary platelet count edema and macrophage polymorphonuclear leukocyte and lymphocyte infiltration as well as inhibits TXNIP/NLRP3 MAPK and NF-KB signaling in a mouse model of LPS-induced acute lung injury from 12 5-50 mg/kg inhibits AChE and induces dyskinesia recovery in a zebrafish model of Alzheimers disease in tank water at 50 g/ml
Cayman Chemical Astlbn 10mg
An inhibitor of plasma kallikrein (Ki 0 81 M) reduces bradykinin generation induced by kaolin and -carrageenan ex vivo in human plasma prolongs partial thromboplastin and euglobulin clot lysis times reduces hyperplasia pannus formation and infiltration of inflammatory cells in the tarsal joint of mice with collagen-induced arthritis
Cayman Chemical Nepodn 10mg
ABlactamase inhibitor (Kis 29-110 nM for class A and class C enzymes) selective for bacterialBlactamases over a panel of mammalian serine proteases (IC50s 1000 M) potentiates the activity of biapenem against K pneumonia expressing KPC-2 at 0 02 g/ml potentiates the activity of carbapenem antibiotics against clinical isolates of various bacteria (MICs 0 06-4 and 4-64 g/ml in the presence and absence of compound respectively) reduces the number of CFUs in the lung in a neutropenic mouse lung infection model when used in combination with biapenem or meropenem at 50 mg/kg
Cayman Chemical Asarone 10mg
Ths mxture contans the prmary COX products produced by most mammalan tssues Contents Prostaglandn D2 Prostaglandn E2 6keto Prostaglandn F1a Prostaglandn F2a and Thromboxane B2 (100 Ug each)
Cayman Chemical Warfarn 10mg
mmunogen Synthetc peptde from the Ctermnal regon of human 5OxoETE receptor Host Rabbt Speces Reactvty ( ) Human Cos7 (Afrcan green monkey) mouse porcne and rat Applcatons CC and WB
Cayman Chemical Warfarn 10mg
Antgen purfed eggshell protens (Zrp and small amounts of zona pellucda protens) from Atlantc salmon (S salar) Host mouse clone MN2B4 CrossReactvty ( ) Atlantc salmon (S salar) (reacts prmarly wth B monomer) ranbow trout (O mykss) and Arctc char (S alpnus) Zrp Applcaton(s) WB and ELSA sotype gG1K
Cayman Chemical Amyrn 10mg
A selective RORa and RORY agonist that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 UM without effect at the related LXR and FXR receptors stabilizes p53 and induces apoptosis in HepG2 cancer cells
Cayman Chemical Caudatn 10mg
A 5-HT1A receptor mixed antagonist and partial agonist inhibits radioligand binding to 5-HT1A sites in rat hippocampal membranes (Ki 2 nM) decreases 5-carboxamidotryptamine-mediated inhibition of forskolin-induced adenylyl cyclase activity in guinea pig hippocampal membranes antagonizes a1-ARs (pA2s 9.47 9.02 and 9.99 in isolated rat tail artery rabbit aorta and rat aorta respectively) decreases blood pressure in anesthetized rats from 1-300 g/kg inhibits phenylephrine-induced pressor responses in pithed rats potentiates the circadian response to light in dark-adapted and entrained hamsters at 5 mg/kg i.p.
Cayman Chemical Alsol B 10mg
Source Active recombinant SARS-CoV-2 N-terminal His-tagged papain-like protease expressed in E coli Amino acids 1564-1880 MW 36 8 kDa
Cayman Chemical Skimmianine 10mg
An internal standard for the quantification of sodium butyrate by GC- or LC-MS
Cayman Chemical Cortol 10mg
An analytical reference standard categorized as a synthetic cannabinoid has been detected in human hair samples tested for verification of drug abstinence intended for research and forensic applications
Cayman Chemical GunosIn 5-trIphosphateso 10mg
The 115 lactone of 17-phenyl-trinor PGF2a with potential for suitable pharmacologic activity and an improved side-effect profile over current glaucoma therapeutics