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Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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Dyneins are a group of microtubule-activated ATPases that function as molecular motors They are divided into two subgroups of axonemal and cytoplasmic dyneins The cytoplasmic dyneins function in intracellular motility including retrograde axonal transport protein sorting organelle movement and spindle dynamics Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains This gene encodes a member of the cytoplasmic dynein heavy chain family
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The protein encoded by this gene is a member of the thiol-specific antioxidant protein family This protein is a bifunctional enzyme with two distinct active sites It is involved in redox regulation of the cell it can reduce H(2)O(2) and short chain organic fatty acid and phospholipid hydroperoxides It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury
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