Protein Analysis Reagents
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).
MilliporeSigma™ Calbiochem™ cFMS Receptor Inhibitor IV
The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PKCε Translocation Inhibitor Peptide
The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Calpain Substrate III, Fluorogenic
A fluorogenic FRET peptide with a substrate sequence that is optimized for calpain-1 and -2.
MilliporeSigma™ Calbiochem™ Caspase-6 Inhibitor II, Cell-Permeable
The Caspase-6 Inhibitor II, Cell-Permeable controls the biological activity of Caspase-6. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ EPAC Inhibitor, ESI-09
A cell-permeable compound that targets cAMP-binding domain of EPAC/cAMP-GEF and inhibits cAMP-dependent EPAC GEF activity (IC50 = 1.4 and 3.2 μM, respectively, against EPAC2 and EPAC1).
MilliporeSigma™ Calbiochem™ Latrunculin A, Latrunculia magnifica
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
MilliporeSigma™ Calbiochem™ Myricetin
A cell-permeable flavanoid that displays anti-inflammatory, anti-diabetic and anti-cancer properties.
MilliporeSigma™ Calbiochem™ sPLA2-IIA Inhibitor I
The sPLA2-IIA Inhibitor I controls the biological activity of sPLA2-IIA. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Merbarone
A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes.
MilliporeSigma™ Calbiochem™ TRPV4 Antagonist I, RN-1734
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ ATIC Dimerization Inhibitor
A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (Ki = 691 nM, Kd = 2
MilliporeSigma™ Calbiochem™ eEF2K Inhibitor, A-484954
The eEF2K Inhibitor, A-484954, also referenced under CAS 142557-61-7, controls the biological activity of eEF2K Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ (-)-Cytisine
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respective
MilliporeSigma™ Calbiochem™ Nrf2 Activator II, AI-1
The Nrf2 Activator II, AI-1, also referenced under CAS 75483-04-4, modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.