Bioactive Small Molecules
Medchemexpress LLC MitoBloCK-10 5mg | 394694-98-5 | 5 MG
MitoBloCK-10 (MB-10) is a small-molecule Tim44 inhibitor that modulates the protein-associated motor (PAM) complex and is used in research to study mitochondrial protein import and related pathways.
- Inhibits Tim44 and attenuates PAM complex activity.
- Useful for studying mitochondrial protein import and quality control.
- Supplied as a solid research-grade compound, typically in a 5 mg pack.
- Molecular formula C12H8FN3O3S and molecular weight 293.27.
Cayman Chemical ANTIBODY AZD 1656 1mg
An HK4 activator; activates HK4 and induces glucose phosphorylation in a cell-free assay (EC50 = 61 nM); decreases blood glucose levels in an OGTT in rats at 0.3 mg/kg; reduces blood glucose levels and increases plasma insulin levels in mice when administered at doses of 2, 4.5, or 9 mg/kg
Cayman Chemical BMS 1166hydrochlorIde 25mg
An inhibitor of the interaction between PD-1 and PDL1 (IC50 = 1.4 nM in a HTRF assay); increases the activation of Jurkat cells expressing PD-1 in co-culture with CHO cells expressing PD-L1 (EC50 = 276 nM in a reporter assay)
Medchemexpress LLC Bradykinin (2-9) | 16875-11-9 | 97.15% | 904.02 | 1 MG
Bradykinin (2-9) is an amino-truncated Bradykinin peptide and a metabolite of Bradykinin, cleaved by Aminopeptidase P.
- Molecular weight: 904.02
- Formula: C44H61N11O10
- Sequence: Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
- Appearance: Solid, white to off-white
- Solubility in DMSO: 100 mg/mL (110.62 mM)
- Below limits of detection in rat kidney and blood in a tissue-based system
Medchemexpress LLC Cabazitaxel | 183133-96-2 | C45H57NO14 | 50 MG
Cabazitaxel is an analytical standard and a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III, offering potential antineoplastic activity for research and analytical applications.
- Intended for research and analytical applications
- Reference standard supplied assay
- Used in qualitative, quantitative, and methodological research
- Commonly used in HPLC, GC, and MS experiments
- Semi-synthetic derivative of natural taxoid 10-deacetylbaccatin III
- Potential antineoplastic activity
Cayman Chemical ANTIBODY DImethoate 100mg
An organophosphate pesticide; acaricidal against Kanzawa spider mites (LC50 = 7 ppm in an aqueous suspension); inhibits purified Kanzawa spider mite AChE (IC50 = 3.3-5.2 nM); reduces motility and viability and induces abnormal morphology in rat sperm from 50-200 μM; increases MDA production and reduces SOD, CAT, and Gpx activities in rat epididymal sperm; decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats at 28 mg/kg per day; induces formation of carcinomas in the adrenal, thyroid, and pituitary glands of male and female rats as well as testicular atrophy, chronic renal disease, polyarteritis, and parathyroid hyperplasia in male rats
Cayman Chemical ANTIBODY DADLE 50mg
A peptide agonist of δ-opioid receptors (Ki = 2.06 nM in a radioligand binding assay); selective for δ-opioid over κ-opioid receptors (Ki = 16,000 nM) but also agonizes of μ-opioid receptors (Ki = 13.8 nM); inhibits electrically induced contractions in guinea pig myenteric plexus and mouse and rat vas deferens (IC50s = 8.9, 0.73, and 134 nM, respectively); induces analgesia in the tail-flick and hot plate tests in mice (ED50s = 0.03 and 0.027 nmol per animal, i.c.v.)
Cayman Chemical ANTIBODY Hexestrol 5g
A synthetic non-steroidal estrogen that binds to ERα and ERβ (Kis = 0.06 and 0.06 nM for the human and rat receptors, respectively); inhibits rat liver microsomal and ox brain phospholipid liposomal lipid peroxidation (IC50s = 1.5 and 2.75 μM, respectively); inhibits porcine microtubule assembly and induces disassembly of preformed microtubules at 50 and 100 μM, respectively, in a cell-free assay; induces kidney tumors in male Syrian hamsters at 25 mg/animal
Enzo Life Sciences Lupeol (50mg). CAS: 545-47-1
Anti-inflammatory, antioxidant and antimutagenic compound. Shows preventive effects on DMBA induced DNA alkylation damage in mouse skin. Modulator of NF-κB and PI(3)K/Akt (protein kinase B; PKB) pathways. Induces Fas-mediated apoptosis via inhibition of Ras signalling. Inhibits tumor growth in mouse in vivo. Alternative name: Fagarasterol, 20(29)-Lupen-3beta-ol, 3beta-Hydroxy-20(29)-lupene. Purity: ≥98% (HPLC). Solubility: Soluble in ether or warm 100% ethanol; insoluble in water. Long Term Storage: -20°C.
Enzo Life Sciences L-Glutathione (oxidized form) (1g). CAS: 27025-41-8
Alternative name: GSSG, (gamma-Glu-Cys-Gly)2. Formula: C20H32N6O12S2. MW: 612.6. Purity: ≥95.0% (HPLC). Appearance: White solid. Formulation: Free acid. MI: 14: 4475. Solubility: Soluble in water. Long Term Storage: +4°C. Handling: Protect from moisture.
Medchemexpress LLC MMP3 inhibitor 3 (TFA) | 158841-76-0 | 99.1% | 686.78 | 5 MG
MMP3 inhibitor 3 (TFA) is an inhibitor of MMP3. MMP3 inhibitor 3 (TFA) can used to study breast cancer.
- Target: MMP