Bioactive Small Molecules
Medchemexpress LLC L-ornithine-d2 hydrochloride | 2483831-42-9 | MFCD12091013 | 99.9% | 170.63 | C5H11D2ClN2O2 | 25 MG
L-ornithine-d2 hydrochloride is the deuterium-labeled analogue of L-ornithine hydrochloride used as a stable-isotope reference standard and tracer in analytical and biochemical workflows. Supplied as a solid with high chemical and isotopic purity, it is intended for mass spectrometry, LC-MS method development, and metabolic tracer studies.
- Deuterium-labeled internal standard for quantitative MS and LC-MS assays.
- High chemical purity (99.9%) and specified isotopic enrichment.
- Solid form, suitable for sealed storage at 4°C to maintain stability.
- Molecular weight 170.63 and formula C5H11D2ClN2O2 for accurate mass calculations.
- Stable in solution when stored at -80°C (up to 6 months) for long-term experiments.
Medchemexpress LLC Sematilide hydrochloride | 101526-62-9 | MFCD11041004 | 99.3% | 349.88 g·mol⁻¹ | C14H24ClN3O3S | 25 MG
Sematilide hydrochloride is the hydrochloride salt of sematilide, a class III antiarrhythmic agent and selective IKr (delayed rectifier K+) channel blocker used in pharmacology research. It inhibits the delayed rectifier K+ current with a reported IC50 of approximately 25 μM and is provided as a high-purity solid for laboratory studies.
- High purity (99.33%).
- Selective IKr (delayed rectifier K+) channel blocker.
- Reported IC50 ≈ 25 μM for delayed rectifier K+ current.
- Molecular weight 349.88 g·mol⁻¹.
- CAS number 101526-62-9.
- Available in milligram-scale pack sizes.
Medchemexpress LLC Fenclozic acid | 17969-20-9 | MFCD00721754 | 99.5% | 253.70 | C11H8ClNO2S | 5 MG
Fenclozic acid is a small-molecule research compound with analgesic, antipyretic, and anti-inflammatory activity. It is supplied for laboratory use as a solid powder and as a DMSO solution. Chemical identity: C11H8ClNO2S; CAS 17969-20-9; mol. wt. 253.70.
- Orally active analgesic, antipyretic, and anti-inflammatory agent.
- High purity suitable for research applications.
- Available in small milligram packages and solution formats.
- Provided with analytical data including COA and SDS.
- Stable under recommended storage conditions when handled per SDS.
AXON MEDCHEM LLC ML2-SA1, EVP-22 10MG
ML2-SA1 is a potent, selective and efficacious activator of TRPML2 with EC50 values of 1.24 μM and 2.38 μM for human and mouse TRPML2, respectively. ML2-SA1 shows high selectivity over h/mTRPML1 and h/mTRPML3 in both calcium imaging and endolysosomal patch-clamp experiments and it does not activate TPC1 nor TPC2.MF C14H13Cl2NOMW 282.17 Purity:100% Soluble in DMSO
Medchemexpress LLC Semaphorin-7A/SEMA7A 100ug | 100ug
Semaphorin-7A/SEMA7A proteins critically regulate integrin-mediated signaling affecting cell migration and immune responses It promotes focal adhesion complex formation activates PTK2/FAK1 and leads to the phosphorylation of MAPK1 and MAPK3 Semaphorin-7A/SEMA7A Protein Mouse (HEK293 His) is the recombinant mouse-derived Semaphorin-7A/SEMA7A expressed by HEK293 with C-6 His labeled tag
![Medchemexpress LLC 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-4-amine | 256376-24-6 | MFCD06411391 | 99.6% | 360.39 g/mol | C20H17FN6 | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237613.png-250.jpg)
Medchemexpress LLC 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-4-amine | 256376-24-6 | MFCD06411391 | 99.6% | 360.39 g/mol | C20H17FN6 | 25MG
This compound is an orally active soluble guanylate cyclase (sGC) activator used in research to increase intracellular cyclic GMP (cGMP) and probe NO-independent sGC signaling. It is supplied as a white to off-white solid suitable for in vitro and in vivo studies, with recommended solubility and storage conditions for reproducible handling.
- Purity 99.6%.
- Molecular formula C20H17FN6; molecular weight 360.4 g/mol.
- Solid form (white to off-white) for powder handling and storage.
- Soluble in DMSO (17.5 mg/mL) for in vitro applications.
- In vivo formulation options include 10% DMSO/40% PEG300/5% Tween-80/45% saline and other vehicles.
- Recommended in vitro concentration 10 μM to increase cGMP in A7r5 cells.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years) or -20°C (1 year).
Medchemexpress LLC 11-bromoundecan-1-ol | 1611-56-9 | MFCD00004752 | 251.21 g/mol | C11H23BrO | 50 G
11-Bromoundecan-1-ol is an ω-brominated primary alcohol used as a synthetic intermediate and PROTAC linker for constructing bifunctional degraders and other small molecules. It is a C11 alkyl bromide with formula C11H23BrO and molecular weight 251.21 g/mol, intended for research and medicinal chemistry applications.
- Useful as a PROTAC linker and linker-building block.
- Primary alcohol and alkyl bromide functional groups enable substitution and coupling reactions.
- Molecular formula C11H23BrO; molecular weight 251.21 g/mol.
- Stable at room temperature for typical storage; store in solvent at low temperature for extended shelf life.
- Supplied in gram-scale packages suitable for synthesis and small-scale research.
Medchemexpress LLC N-succinimidyl 3-(acetylthio)propionate | 84271-78-3 | MFCD00133023 | ≥98.0% | 245.25 g/mol | C9H11NO5S | 1 G
3-(Acetylthio)propionic acid N-succinimidyl ester is an N-hydroxysuccinimide (NHS) ester reagent that installs an acetyl-protected thiol onto primary amines. After deacetylation, the resulting thiol is available for conjugation, crosslinking, or linker synthesis in biomolecular and organic chemistry.
- Introduces an acetyl-protected thiol onto amine-containing molecules for controlled thiol installation.
- Allows deprotection to reveal free thiols for downstream conjugation and crosslinking.
- Compatible with peptide and protein modification workflows.
- Supplied as a stable solid for convenient storage and handling.
- High purity supports reproducible coupling and reduced side reactions.
Medchemexpress LLC Osilodrostat (phosphate) | 1315449-72-9 | 98.8% | 325.23 | 5 MG
Osilodrostat (LCI699) phosphate is a potent, orally active 11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is also a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. It inhibits aldosterone and corticosterone synthesis and has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS).
- Potent, orally active 11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM.
- Potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM (human) and 160 nM (rat).
- Inhibits aldosterone and corticosterone synthesis.
- Has blood pressure lowering ability.
- Can be used for research of Cushing syndrome (CS).
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | MFCD35200285 | 99.7% | 333.39 g/mol | C19H19N5O | 50MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor (CAS 1643947-30-1) used in epigenetic and oncology research. It inhibits BRD4 bromodomain 1 binding to tetra-acetylated histone H4 and demonstrates cellular activity (reported IC50 ≤ 0.3 μM). Supplied as a powder with recommended storage at -20°C (powder) and in solvent at -80°C (6 months) or -20°C (1 month). Formula: C19H19N5O; molecular weight: 333.39 g/mol; reported purity ~99.7%.
- Inhibits BRD4 bromodomain 1 with cellular activity (IC50 ≤ 0.3 μM).
- High reported purity suitable for research applications.
- Stable as a powder at -20°C for extended storage.
- Solvent aliquots stable at -80°C for six months or -20°C for one month.
- Offered in multiple pack sizes including 50 MG for convenience.
Cayman Chemical N 3hydroxy7cIs tetradecen 5mg
An AHL involved in quorum sensing; did not affect cytokine or antibody production in mouse and human leukocyte immunoassays using LPS-stimulated macrophages
Medchemexpress LLC NS-638 | 150493-34-8 | MFCD00920837 | 99.8% | 325.72 | C15H11ClF3N3 | 100 MG
NS-638 is a small nonpeptide Ca2+-channel blocker used in research to study voltage-gated calcium channel-mediated signaling. It inhibits K+-stimulated intracellular calcium elevation (reported IC50 ≈ 3.4 μM) and shows activity in synaptosome uptake and neuronal release assays. Provided as a solid with high reported purity, it is intended for laboratory research use only.
- Blocks K+-stimulated intracellular Ca2+ elevation (IC50 ≈ 3.4 μM).
- Shows activity in synaptosome uptake and AMPA-stimulated GABA release assays.
- Solid form, high purity suitable for biochemical assays.
- Molecular weight 325.72, formula C15H11ClF3N3.
- For research use only; not for human or veterinary applications.
Medchemexpress LLC (Benzothiazol-2-ylthio)methyl thiocyanate | 21564-17-0 | MFCD00072503 | 88.7% | 238.35 | C9H6N2S3 | 10 MG
TCMTB (Benzothiazol-2-ylthio)methyl thiocyanate is an antifouling agent and an emerging contaminant supplied as a research chemical. Provided as a yellow to brown liquid, it is used in studies of environmental contamination, biocidal activity, and material preservation. Handle per safety data sheet and store under inert atmosphere.
- CAS number 21564-17-0.
- Molecular formula C9H6N2S3.
- Molecular weight 238.35 g/mol.
- Purity 88.7%.
- Physical state liquid; appearance yellow to brown.
- Recommended storage 4°C under nitrogen.
- Stability in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.