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Filtered Search Results
Selleck Chemical LLC XCT790 S0407-5MG
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XCT-790 (Compound 12) is a potent and selective inverse agonist for estrogen-related receptor (ERR ) with IC50 of 0 37 M XCT-790 (Compound 12) is inactive against ERR and the estrogen receptors ER and ER XCT-790 (Compound 12) significantly inhibits in vivo tumor growth and angiogenesis and induces apoptosis
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Selleck Chemical LLC Ferrostatin-1 (Fer-1) 5mg 347174-05-4
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Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Fenebrutinib
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Fenebrutinib (GDC-0853) is a potent selective and non-covalent bruton s tyrosine kinase (BTK) inhibitor with an Ki value of 0 91 nM for Btk with 100-fold selectivity over 3 off-targets (Bmx 153-fold Fgr 168-fold Src 131-fold)
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Selleck Chemical LLC R406 5mg 841290-81-1
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R406 is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Cayman Chemical DC-LC3n-D5 5mg
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An inhibitor of LC3 (IC50 = 200 nM); selectively binds to LC3-I and LC3-II over GABARAP, SCARB2, and PON2 in an ABPP assay using HeLa cells; inhibits LC3-II lipidation, autophagosome formation, and the protein-protein interaction between LC3-II and ATG7 in HeLa cells at 25 µM
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Selleck Chemical LLC BRD0705 S9638-5MG
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BRD0705 is a potent paralog selective and orally active inhibitor of GSK3 (Glycogen synthase kinase 3 ) with IC50 of 66 nM and Kd of 4 8 M BRD0705 also inhibits GSK3 with IC50 of 515 nM BRD0705 can be used for acute myeloid leukemia (AML)
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Cayman Chemical ANTIBODY PhenytoIn 50g
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An anticonvulsant agent and active metabolite of fosphenytoin; inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner; reduces the neuronal firing frequency and decreases the amplitude of EPSPs in electrically stimulated rat corticostriatal slices (EC50s = 42.8 and 33.5 µM, respectively); protects against MES-induced seizures in mice (ED50 = 10 mg/kg)
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Cayman Chemical ANTIBODY n-CHMIMO 1mg
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An analytical reference standard categorized as a synthetic cannabinoid; has been detected in human hair samples tested for verification of drug abstinence; intended for research and forensic applications
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Apexbio Technology LLC Telaprevir (VX-950), 25mg. Cas: 402957-28-2 MFCD: MFCD11616089. HCV NS3-4A protease inhibitor
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Telaprevir (also known as VX-950), derived from the viral NS5A/5B substrate of the protease through structure-based techniques, is a novel and potent inhibitor of hepatitis C virus (HCV) NS3-4A protease 402957-28-2. MFCD11616089
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Medchemexpress LLC Rehmannioside C | 81720-07-2 | 1 MG
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Rehmannioside C is an iridoid glucoside isolated from Radix Rehmanniae Praeparata. It is intended for research use only.
- Purity of 99.47%
- Solid form, white to light yellow color
- Isolated from plants, specifically Scrophulariaceae and Rehmannia glutinosa
- Soluble in DMSO (50 mg/mL)
- Suitable for in vivo dissolution protocols
- Classified as a natural product standard, terpenoid, and iridoid
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Selleck Chemical LLC L-778123 hydrochloride E4620-100MG
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L-778123 hydrochloride is a potent dual inhibitor of farnesyl protein transferase (FPTase) with an IC50 of 2 nM and geranylgeranyl protein transferase I (GGPTase-I) with an IC50 of 98 nM It also displays promising anti-leukemia activity
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Medchemexpress LLC Fraxin (Fraxoside) | 524-30-1 | MFCD00010093 | 370.31 | 1 ML
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Fraxin, also known as Fraxoside, is isolated from Cortex Fraxini and is a glucoside of fraxetin. It is reported to possess potent anti-oxidative stress, anti-inflammatory, and antimetastatic properties through the inhibition of cyclo AMP phosphodiesterase enzyme.
- Possesses anti-oxidative stress action
- Exhibits anti-inflammatory properties
- Shows antimetastatic properties
- Inhibits cyclo AMP phosphodiesterase enzyme
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Selleck Chemical LLC EGNHS E7189-50MG
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EGNHS is a proteolytic targeting chimera (PROTAC) linker belonging to the alkyl/ether class used in the synthesis of PROTAC molecules It can form a cross-link between Lys232 and Lys241 of horseradish peroxidase C (HRP) and modify Lys174 without cross-linking
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Medchemexpress LLC Wedelolactone | 524-12-9 | 314.25 | 1 ML
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Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK Complex. It also inhibits 5-lipoxygenase (5-Lox) with an IC50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. It can be extracted from Eclipta alba and is used for cancer research.
- Suppresses LPS-induced caspase-11 expression
- Inhibits 5-lipoxygenase (5-Lox)
- Induces caspase-dependent apoptosis in prostate cancer cells
- Downregulates PKCε without inhibiting Akt
- Suitable for cancer research
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Selleck Chemical LLC Chilipepper Extract E3400-5MG
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Chili Pepper Extract is extrcated from Capsicum annuum which is a good remedy for various medical conditions such as increased blood pressure and high levels of serum triglycerides and cholesterol myocardial infarction arthritis and migraines
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