Bioactive Small Molecules
Apexbio Technology LLC Epinephrine HCl, 5g Cas# 55-31-2
Epinephrine HCl is a hormone and a neurotransmitter. 55-31-2. MFCD00801067 Epinephrine HCl is a hormone and a neurotransmitter. There are other sizes available. Please inqury us for quote.
Medchemexpress LLC HY-W011082 50mg Medchemexpress, NLRP3-IN-2 CAS:16673-34-0 Purity:>98%
Medchemexpress, HY-W011082 50mg NLRP3-IN-2 CAS:16673-34-0 NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1443246-62-5 | Medchem Express | ML 297 | 5mg | 506403686 | HY-110192 | MFCD27977571 | 328.323 | C17H14F2N4O
Ambeed | 3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid | 100mg | 490553026 | A312735 | 195877-90-8 | MFCD02179070 | 406.479 | C21H30N2O6
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eMolecules 2165322-94-9 | Medchem Express | USP25/28 inhibitor AZ1 | 5mg | 495799959 | HY-117370 | 422.218 | C17H16BrF4NO2
Medchem Express | IR415 | 5mg | 572596587 | HY-116999 | 452967-14-5 | MFCD00238878 | 296.340 | C13H14F2N4S
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Cayman Chemical SclerotIorIn 5mg
A natural product that inhibits soybean LO-1 (IC50 = 4.2 µM), cholesterol ester transfer protein (IC50 = 19.4 µM), Grb2-Shc interaction (IC50 = 22 µM), and antagonizes endothelin receptors (IC50 = 114 and 152 µM for human ETA and ETB, respectively)
Cayman Chemical ANTIBODY DBO-83 1mg
An agonist of nAChRs with antinociceptive and anti-amnesic activities; binds to nAChRs in rat cortical membranes (Ki = 4.1 nM); dose-dependently increases the latency to paw licking in mice in the hot plate test and reduces the number of abdominal constrictions in mice in the acetic acid abdominal constriction test; dose-dependently prevents amnesia induced by mecamylamine, scopolamine, and dihydro-β-erythroidine in mice in the passive avoidance test
Cayman Chemical BB22 6hydroxyIsoquInolIn I 5mg
Differs from BB-22 structurally by having the quinoline group replaced with an isoquinoline group attached at its six position; intended for forensic and research applications
Cayman Chemical ANTIBODY NItracaIn 10mg
A structural analog of the dopamine reuptake inhibitor, dimethocaine; intended for forensic and research applications
Cayman Chemical ANTIBODY DaphntIn 25mg
A coumarin derivative with diverse biological activities; inhibits EGFR, PKA, and PKC in vitro (IC50s = 7.67, 9.33, and 25.01 µM, respectively); inhibits cell proliferation (IC50 = 73 µM) in MCF-7 breast carcinoma cells; decreases the generation of ROS and production of MDA and increases SOD activity and the GSH:GSSG ratio in RAW 264.7 cells; prevents t-BHP-induced cytotoxicity and ROS overproduction in wild-type, but not Nrf2-/-, RAW 264.7 cells and increases the expression of proteins downstream of Nrf2
Cayman Chemical ANTIBODY JYL1421 1mg
A TRPV1 antagonist; inhibits capsaicin-induced calcium uptake in CHO cells expressing rat TRPV1 (EC50 = 9.2 nM); inhibits capsaicin-induced release of somatostatin, substance P, and CGRP from isolated rat trachea (IC50s = 227-491 nM); inhibits capsaicin-induced hypothermia and hypotension in rats at 2 and 0.4 mg/kg, respectively; reduces the number of wiping movements induced by ocular administration of capsaicin in rats at 2 mg/kg
Cayman Chemical ANTIBODY CelocIdIn 25mg
An antibiotic; active against various bacterial strains, including M. tuberculosis, and trypanosomes; inhibits proliferation of EBV-transformed cells, activates the c-Myc and NF-κB pathways in vitro, and induces necrotic cell death in gammaherpes virus-infected B cells; protective against bacterial leaf blight in rice plants (100-200 ppm); inhibits α-ketoglutarate in X. oryzae (1 ppm)
eMolecules 393121-74-9 | AA 147 | Tocris Bioscience (Bio-Techne US) | MFCD01881999 | 255.317 | C16H17NO2 | 98.000 | Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1 | 5mg | 445480690
AA 147 | Tocris Bioscience (Bio-Techne US) | 393121-74-9 | MFCD01881999 | 255.317 | C16H17NO2 | 98.000 | Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1 | 5mg | 445480690
Medchemexpress LLC GNE-131 | 1629063-81-5 | 98.2% | 442.57 | 1 ML
GNE-131 is a potent and selective inhibitor of human sodium channels, specifically targeting NaV1.7 with an IC50 of 3 nM. This compound has demonstrated excellent potency and good in vitro metabolic stability. It also exhibits low in vivo clearance in mouse, rat, and dog models, along with excellent efficacy in a transgenic mouse model of induced pain.
- Potent and selective sodium channel inhibition.
- Good metabolic stability in laboratory settings.
- Effective in pain models.
- Low clearance in multiple animal species.
![Medchemexpress LLC Phenol, 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]- | 2009273-67-8 | 99.9% | 330.38 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439827-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Phenol, 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]- | 2009273-67-8 | 99.9% | 330.38 | 100 MG
GNE-6640 is a selective and non-covalent inhibitor of ubiquitin specific peptidase 7 (USP7). It has IC50 values of 0.75 μM for full length USP7, 0.43 μM for USP7 catalytic domain, 20.3 μM for full length USP47, and 0.23 μM for Ub-MDM2.
- Promotes endogenous MDM2 ubiquitination with Lys48 (K48)-linked polyubiquitin chains.
- Targets cellular USP7, MDM2, and p53 signaling pathways.
- Decreases viability of 108 cell lines with IC50 ≤ 10 μM.
- Can be combined with doxorubicin or cisplatin to enhance USP7 inhibitor efficacy.
- Induces tumor cell death.
- Enhances cytotoxicity with chemotherapeutic agents and targeted compounds.
Meridian Life Science RNase Inhibitor Glycerol Free, 50ML
RNase Inhibitor (Glycerol-Free) is from a recombinant protein that inhibits different RNases (A, B, C) by binding non-covalently in a 1:1 ratio. With an association constant of 10^14 M, it is useful in any applications where the presence of RNases is a potential problem. RNase Inhibitor (Glycerol-Free) is tested for activity, SDS-PAGE purity and the absence of endonucleases, nickases and exonuclease. RNase Inhibitor (Glycerol Free) delivers excellent, stable performance without glycerol, allowing you to deliver reliable results with the added capability for lyophilization for ambient temperature storage and shipment.