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Filtered Search Results
Medchemexpress LLC HY-B0627 25mg , Metformin CAS:657-24-9 Purity:>98%
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HY-B0627 25mg Metformin CAS: 657-24-9 Metformin (1,1-Dimethylbiguanide) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin can cross the blood-brain barrier and triggers autophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Diabzi sting agonist-1 | 2138498-18-5 | MFCD31746907 | 99.9% | 849.94 g/mol | C42H51N13O7 | 5 MG
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diABZI STING agonist-1 (tautomerism) is a non-nucleotide small-molecule agonist of the STING (stimulator of interferon genes) signaling pathway. It activates STING with reported EC50 values of 130 nM (human) and 186 nM (mouse), is supplied for research use only, and is provided in a small-scale research vial.
- Potent STING receptor agonist with low-nanomolar activity
- Reported EC50 values: human 130 nM, mouse 186 nM
- High chemical purity (99.9%)
- Molecular weight 849.94 g/mol; formula C42H51N13O7
- Supplied as a 5 mg research vial
- Used in studies demonstrating STING-dependent activation in vivo and in vitro
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Medchemexpress LLC Ferric oxide, yellow | 51274-00-1 | MFCD00011008 | Fe2O3·H2O | 50 G
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Ferric oxide, yellow is an excipient that can be used as a colorant in pharmaceutical preparations. It is generally an inactive ingredient used to improve stability, solubility, and processability, and can influence the absorption, distribution, metabolism, and elimination processes of co-administered drugs.
- Provides color uniformity
- Masks odors
- Functions as a light blocker to protect photosensitive components
- Can serve as an iron supplement in some nutritional supplements
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Medchemexpress LLC HY-112037 10mg , IACS-010759 CAS:1570496-34-2 Purity:>98%
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HY-112037 10mg IACS-010759 CAS: 1570496-34-2 IACS-010759 is an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 has the potential for relapsed/refractory AML and solid tumors research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10182 50mg , Laduviglusib CAS:252917-06-9 Purity:>98%
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HY-10182 50mg Laduviglusib CAS: 252917-06-9 Laduviglusib (CHIR-99021) is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib enhances mouse and human embryonic stem cells self-renewal. Laduviglusib induces autophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-134582 5mg , dCBP-1 CAS:2484739-25-3 Purity:>98%
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HY-134582 5mg dCBP-1 CAS: 2484739-25-3 dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and ablates oncogenic enhancer activity driving MYC expression. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC leniolisib S8752-25MG
Leniolisib (CDZ 173) is a potent PI3K selective inhibitor with biochemical IC50 values of 0 244 0 424 2 23 and 0 011 M for PI3K PI3K PI3K and PI3K respectively
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STEMCELL Technologies StemRegenin 1 (Hydrochloride), Size: 5 mg
Promote the maintenance and expansion of human hematopoietic stem cells in culture (Boitano et al. Science 2010 Csaszar et al. Cell Stem Cell 2012) with StemRegenin 1 (Hydrochloride). StemRegenin 1 is an antagonist of the aryl hydrocarbon receptor (AHR). It promotes ex vivo expansion of CD34 human hematopoietic stem cells and the generation of CD34 hematopoietic progenitor cells from non-human primate induced pluripotent stem cells. StemRegenin1 is also used in stimulating the differentiation of CD34 hematopoietic progenitor cells into functional human dendritic cells (Thordardottir et al. Stem Cells Dev 2014) and promoting hematopoietic differentiation of induced pluripotent stem cells (iPSCs) (Gori et al. Blood 2012). Together with UM729 it is also used in preventing differentiation of AML cells in culture. StemRegenin 1 is supplied as the hydrochloride salt of the molecule with ≥ 98% purity Molecu
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Selleck Chemical LLC Rosmarinic acid 25mg 20283-92-5 Rosemary acid
Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-? activity in NF-?B activation signaling. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Salmeterol 5mg 89365-50-4 Astmerole, GR-33343X, SN408D
Salmeterol (Astmerole, GR-33343X, SN408D) is a long-acting beta2-adrenergic receptor agonist with Ki value of 1.5 nM for WT ?2AR and shows very high selectivity for the WT ?2AR(?1Ki/?2Ki ratio of approximately 1500). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC GSK2982772 2mg 1622848-92-3
GSK2982772 is an ATP competitive receptor-interacting protein-1 (RIP1) kinase (RIPK1) inhibitor with the IC50 value of 16 nM. It has exquisite kinase specificity and excellent activity in blocking many TNF-dependent cellular responses. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC FIN56 5mg 1083162-61-1
FIN56 is a specific inducer of ferroptosis . *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Doxycycline 25mg 564-25-0 Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum
Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Diphenyleneiodonium chloride (DPI) 10mg 4673-26-1
Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and also a potent, irreversible, and time-, temperature-dependent iNOS/eNOS inhibitor. Diphenyleneiodonium chloride (DPI) also functions as a TRPA1 activator and selectively inhibits intracellular reactive oxygen species (ROS). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Bedaquiline 10mg 843663-66-1 TMC-207, R207910
Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000). *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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