Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,106 – 6,120 of 60,541 results

6,106

Selleck Chemical LLC BMS-986397 E4725-25MG

BMS-986397 (CC-91633) is a potent and selective thalidomide-derived molecular glue degrader of CK1 and a modulator of CRBN E3 ubiquitin ligase As a first-in-class CELMoD agent it exhibits strong anti-leukemic activity in AML (Acute Myeloid Leukemia) and HR-MDS (High-Risk Myelodysplastic Syndrome) models with enhanced efficacy and potency for hematologic malignancies and immunomodulation

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6,107

Medchemexpress LLC HY-111759 5mg Medchemexpress, Jaspamycin CAS:22242-96-2 Purity:>98%

Medchemexpress, HY-111759 5mg Jaspamycin CAS:22242-96-2 Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,108

Lkt Laboratories PACLITAXEL, SEMI-SYNTHETIC

PACLITAXEL, SEMI-SYNTHETIC, 100MG, CAS# 33069-62-4, PURITY 98%

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6,109

Medchemexpress LLC HY-139214 10mg , IXA4 CAS:1185329-96-7 Purity:>98%

HY-139214 10mg IXA4 CAS: 1185329-96-7 IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,110

TARGETMOL CHEMICALS INC SOTORASIB 10MG

Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sotorasib (AMG-510) is a selective and orally bioavailable KRAS G12C covalent inhibitor. purity: 99%

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6,111

Cayman Chemical 1-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol, Purity: ≥98%, CAS: 1122578-89-5, 5 mg

A triacylglycerol containing myristic, palmitic, and butyric acids at the sn-1, sn-2, and sn-3 positions, respectively; has been detected in human breast milk

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6,112

Medchemexpress LLC Hgpr91 antagonist 1 | 1314796-00-3 | 99.9% | 529.53 g/mol | C31H23F4N3O | 50MG

hGPR91 antagonist 1 (Compound 4c) is a potent, selective antagonist of the human G protein-coupled receptor 91 (hGPR91/SUCNR1) with an IC50 of 7 nM. Supplied as a high-purity solid, the compound is suitable for in vitro and in vivo pharmacology and receptor profiling studies. The molecular formula is C31H23F4N3O and the molecular weight is 529.53 g/mol.

Potent and selective antagonist of human GPR91 (IC50 7 nM).
Chemical formula C31H23F4N3O and molecular weight 529.53 g/mol.
High purity (99.9%) suitable for research use.
White to off-white solid form for easy handling.
Stable as a powder at -20°C for long-term storage.
Available in small milligram pack sizes for preclinical work.

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6,113

Cayman Chemical C-DIM8, Purity: ≥95%, CAS: 151358-47-3, 5 mg

A Nur77 antagonist; inhibits C-DIM5-induced reporter gene expression in PANC-28 cells at 20 µM; reduces expression of BIRC5 in PANC-1 cells at 10, 15, and 20 µM; induces tumor cell apoptosis and reduces tumor volume in an L3.6pl pancreatic carcinoma mouse xenograft model at 30 mg/kg

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6,114

Cayman Chemical NVS-PAK1-1, Purity: ≥98%, CAS: 1783816-74-9, 10 mg

An allosteric inhibitor of PAK1 (Kd = 7 nM); has an IC50 value of 5.2 nM in a PAK1 dephosphorylation assay; selective for PAK1 over PAK2 (Kd = 400 nM) and over a panel of 442 kinases; inhibits phosphorylation of MEK Ser289 at 6-20 µM but does not inhibit proliferation of Su86.86 cells at concentrations lower than 2 µM

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6,115

Cayman Chemical Tipranavir, Purity: ≥95%, CAS: 174484-41-4, 1 mg

A nonpeptidic HIV aspartyl protease inhibitor (Ki = < 1 nM)

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6,116

Medchemexpress LLC HY-114091 1mg Medchemexpress, PF-00356231 (hydrochloride) CAS:820223-77-6 Purity:>98%

Medchemexpress, HY-114091 1mg PF-00356231 (HCl) CAS:820223-77-6 PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,117

Selleck Chemical LLC BMS-986365 E1964-100MG

BMS-986365 (CC-94676) is a potent and selective heterobifunctional ligand-directed degrader (LDD) and antagonist of androgen receptor (AR) that effectively targets both wildtype and mutant forms of the androgen receptor (AR) in the cytoplasm and nucleus It rapidly degrades AR suppresses AR signaling and shows promising clinical activity in inhibiting tumor growth in patients with metastatic castration-resistant prostate cancer (mCRPC)

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6,118

Medchemexpress LLC 1-(3-hydroxypropyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione | 59413-14-8 | MFCD01682404 | 25mg

Pentoxifylline impurity 1 is an impurity of Pentoxifylline (HY-B0715)

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6,119

eMolecules 175717-75-6 | [(2S)-2-AMINOPROPOXY](TERT-BUTYL)DIMETHYLSILANE | AstaTech | MFCD26386284 | 189.374 | C9H23NOSi | 95.000 | C[C@H](N)CO[Si](C)(C)C(C)(C)C | 1g | 573027326

[(2S)-2-AMINOPROPOXY](TERT-BUTYL)DIMETHYLSILANE | AstaTech | 175717-75-6 | MFCD26386284 | 189.374 | C9H23NOSi | 95.000 | C[C@H](N)CO[Si](C)(C)C(C)(C)C | 1g | 573027326

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6,120

Cayman Chemical 4-Methoxyphenylacetone, Purity: ≥98%, CAS: 122-84-9, 5 mg

An analytical reference standard categorized as a precursor in the synthesis of amphetamines; intended for research and forensic applications

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Bioactive Small Molecules

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Medchemexpress LLC HY-111759 5mg Medchemexpress, Jaspamycin CAS:22242-96-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-139214 10mg , IXA4 CAS:1185329-96-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hgpr91 antagonist 1 | 1314796-00-3 | 99.9% | 529.53 g/mol | C31H23F4N3O | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-114091 1mg Medchemexpress, PF-00356231 (hydrochloride) CAS:820223-77-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-(3-hydroxypropyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione | 59413-14-8 | MFCD01682404 | 25mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-111759 5mg Medchemexpress, Jaspamycin CAS:22242-96-2 Purity:>98%

Medchemexpress LLC HY-139214 10mg , IXA4 CAS:1185329-96-7 Purity:>98%

Medchemexpress LLC Hgpr91 antagonist 1 | 1314796-00-3 | 99.9% | 529.53 g/mol | C31H23F4N3O | 50MG

Medchemexpress LLC HY-114091 1mg Medchemexpress, PF-00356231 (hydrochloride) CAS:820223-77-6 Purity:>98%

Medchemexpress LLC 1-(3-hydroxypropyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione | 59413-14-8 | MFCD01682404 | 25mg