Isotopically Labeled Compounds
Medchemexpress LLC Clozapine-d8 | 1185053-50-2 | MFCD09752113 | 99.7% | 334.87 | C18H11D8ClN4 | 5 MG
Clozapine-d8 is the deuterium-labeled isotopologue of the antipsychotic clozapine, provided as a high-purity analytical standard for research use. It is intended as an internal standard for quantitative bioanalytical methods and preclinical studies where accurate measurement of clozapine is required.
- Deuterium-labeled internal standard for accurate quantitation.
- Suitable for LC-MS/MS and GC-MS analytical methods.
- High purity (≈99.7%).
- Provides improved assay precision and recovery.
- Supplied in small quantities appropriate for analytical standards.
Medchemexpress LLC L-Tryptophan-α,β,β,2,4,5,6,7-d8 | 1233395-93-1 | 212.27 | 25 MG
L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. It is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into drug molecules for quantitation during drug development
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC N-tert-butoxycarbonyl-2-aminoacetic acid-d2 | 42492-65-9 | MFCD01074012 | 98.0% | 177.19 | C7H11D2NO4 | 10mg
Boc-Glycine-d2 is the deuterium labeled Boc-Glycine[1]
Medchemexpress LLC 1-bromoheptane-d5 | 1219805-66-9 | 184.13 | C7H10D5Br | 10 MG
1-Bromoheptane-d5 is the deuterium-labeled analogue of 1-bromoheptane used as an isotopic tracer and internal standard in analytical and synthetic chemistry. Supplied as a liquid with molecular formula C7H10D5Br and molecular weight 184.13, it is provided in mg-scale quantities suitable for mass spectrometry, quantitation, and deuterium-labeling studies.
- Deuterium-labeled for use as an isotopic tracer and internal standard.
- Suitable for mass spectrometry quantitation and method validation.
- Provided in mg-scale quantities for analytical workflows.
- Liquid form facilitates accurate spiking and sample preparation.
- Molecular formula C7H10D5Br and CAS 1219805-66-9 for unambiguous identification.
Medchemexpress LLC Propazine-d14 | 1219802-87-5 | 99.0% | 5 MG
Propazine-d14 is a deuterium labeled Propazine, intended for research use only. It can serve as a tracer or an internal standard for quantitative analysis in various analytical techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes like deuterium are incorporated into drug molecules primarily for quantitation during drug development and can also influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes to aid in drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Hypericin-d10 | 548-04-9 | 95.3% | 514.50 | C30H6D10O8 | 10 MG
Hypericin-d10 is the deuterium-labeled analogue of hypericin, provided for research use as a stable isotope tracer or internal standard in analytical workflows. It is intended for quantitative and pharmacokinetic studies using techniques such as NMR, GC-MS, and LC-MS, and exhibits the characteristic photosensitive biological activity of hypericin derivatives.
- Deuterium-labeled tracer for quantitative analysis.
- Suitable as internal standard for NMR, GC-MS, and LC-MS.
- Reported purity of 95.3% supports analytical applications.
- Solid, brown to black appearance; store under recommended conditions for stability.
- Molecular formula C30H6D10O8 and molecular weight 514.50 aid reference and calculations.
Medchemexpress LLC Sucrose-13C | 99.5% | 343.29 g/mol | C1113CH22O11 | 5mg
Sucrose-13C is 13C labeled Sucrose Sucrose (D-( )-Saccharose) is a disaccharide which is composed of two monosaccharides glucose and fructose Sucrose can be applied in some animal models including metabolic disease obesity diet on preference and diabetes et al[1]
Medchemexpress LLC Ethionamide-d3 | 2748267-66-3 | >=99% | 1 MG
Ethionamide-d3 is the deuterium labeled Ethionamide, an antibiotic utilized in the treatment of tuberculosis. This compound is intended for research use only and can be employed as a tracer or an internal standard for quantitative analysis. Deuteration, the incorporation of stable heavy isotopes, has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Active against *M. tuberculosis*.
- Not for human or veterinary use.
Medchemexpress LLC Salbutamol-d9 acetate (Albuterol-d9 acetate) | 1781417-68-2 | 99.5% | 1 MG
Salbutamol-d9 (Albuterol-d9) acetate is the deuterium-labeled form of Salbutamol, an orally active, short-acting β2-adrenergic receptor agonist. It promotes tumorigenesis in gastric cancer cells via the β2-AR/ERK/EMT pathway and can relax bronchial smooth muscle, used in studies of bronchospasm induced by asthma and chronic obstructive pulmonary disease. It is for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
- May affect pharmacokinetic and metabolic profiles of drugs through deuteration
Cayman Chemical GlycohyocholIc AcId-d4 1mg
An internal standard for the quantification of glycohyocholic acid by GC- or LC-MS
Medchemexpress LLC 1-Pyrrolidine-2,2,3,3,4,4-d6-acetamide, α-ethyl-5-oxo-, (αS)- | 1133229-30-7 | 98.7% | 176.25 | 100 MG
Levetiracetam-d6 (ring-d6) is an internal standard designed for determining Levetiracetam content in whole blood. This product is for research use only and not sold to patients.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Olmesartan-d4 (RNH-6270-d4) | 1420880-41-6 | 98.8% | 450.53 | 1 MG
Olmesartan-d4 is a deuterium-labeled form of Olmesartan, an angiotensin II receptor (AT1R) antagonist primarily used for treating high blood pressure.
- Functions as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled compound.
- Angiotensin II receptor (AT1R) antagonist.
- Aids in the treatment of high blood pressure.
Medchemexpress LLC Alpha-D-glucose-13C | 287100-64-5 | 99.4% | 100 MG
Alpha-D-glucose-13C is a 13C labeled alpha-D-glucose, which is an endogenous metabolite. It is intended for research use only, not for medical applications.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes as tracers for quantitation during drug development
Medchemexpress LLC Caspofungin-d4 | 1131958-73-0 | 1097.34 | 500 UG
Caspofungin-d4 is a deuterium-labeled version of Caspofungin, a potent antifungal agent. It works by inhibiting the synthesis of β-(l,3)-D-glucan, a crucial component of the fungal cell wall. This compound is intended for research use only and is not for patient administration. Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled.
- Potent antifungal agent.
- Inhibits synthesis of fungal cell wall component β-(l,3)-D-glucan.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Pacritinib-d4 | 476.60 | 5 MG
Pacritinib-d4 (SB1518-d4) is the deuterium labeled Pacritinib. It is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). This compound also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). Stable heavy isotopes have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Potent inhibitor of wild-type JAK2 and JAK2V617F mutant
- Inhibits FLT3 and its mutant FLT3D835Y
- Used as a tracer for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles