Isotopically Labeled Compounds
Medchemexpress LLC Levamlodipine-d4 | 1346617-19-3 | 99.7% | 412.90 | 500 UG
Levamlodipine-d4 is the deuterium labeled Levamlodipine. Levamlodipine ((S)-Amlodipine) is a potent dihydropyridine calcium channel blocker that possesses vasodilation properties and is used in the treatment of hypertension and angina.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into the drug molecule, primarily as tracers for quantitation during drug development.
- Deuteration may affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Repaglinide-d5 | 1217709-85-7 | C27H31D5N2O4 | 50 MG
Repaglinide-d5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted.
Medchemexpress LLC Diethylamine-d10hydr 50mg
Diethylamine-d10 hydrobromide is the deuterium labeled Diethylamine hydrobromide[1]
Medchemexpress LLC L-Asparagine-15N2 monohydrate | 287484-32-6 | 152.12 | 5 MG
L-Asparagine-15N2 monohydrate is the 15N-labeled version of L-Asparagine monohydrate. L-Asparagine monohydrate is an essential amino acid for leukemic cells and serves as a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that depletes asparagine (Asn) and glutamine (Gln), thereby inhibiting protein biosynthesis in lymphoblasts. The removal of L-asparagine from plasma by L-Asparaginase leads to inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase demonstrates cell-killing ability both in vitro and in vivo, selectively inhibiting the growth of cancer cells that have low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can also be utilized as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories D-XYLOSE (1,2-13C2, 99%), 0.25 G, 201741-00-6
D-XYLOSE (1,2-13C2, 99%), 0.25 G, 201741-00-6
Cayman Chemical DabIgatrn-13C-d3 1mg
An internal standard for the quantification of dabigatran by GC- or LC-MS
Cambridge Isotope Laboratories Sodium Pyruvate | 142014-11-7 | MFCD00084084 | 0.5g
Sodium Pyruvate | Putity: 98% | MW: 113.02 | 142014-11-7 | MFCD00084084 | 0.5g
Medchemexpress LLC DL-alanine-d3 | 53795-94-1 | MFCD00084106 | 98.0% | 92.11 g/mol | C3H4D3NO2 | 10 MG
DL-Alanine-d3 is a deuterium-labeled form of the amino acid alanine provided as a solid for analytical and tracer applications. It is used as an internal standard and isotopic tracer in mass spectrometry, metabolomics, and method development where precise quantitation and tracking of alanine are required.
- Deuterium-labeled analog for use as an internal standard.
- High chemical and isotopic purity suitable for quantitative analysis.
- Available in small, premeasured amounts for analytical workflows.
- Suitable for mass spectrometry, metabolomics, and tracer studies.
- Stable solid form for straightforward storage and handling.
Medchemexpress LLC (Rac)-Bedaquiline-d6 | 2517573-53-2 | 99.0% | 561.54 | 1 MG
(Rac)-Bedaquiline-d6 is a deuterium-labeled version of Bedaquiline that inhibits *Mycobacterium tuberculosis* F1FO-ATP synthase. It exhibits uncoupler activity and is used for multi-agent resistant tuberculosis. Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) | 2734410-01-4 | 151.14 | 100 UG
Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is the 13C labeled Cinnamic acid, which has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. It incorporates stable heavy isotopes for quantitation during drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical AldIcarb sulfon 250mg
A metabolite and degradation product of aldicarb; reduces the number of male T. semipenetrans second-stage larvae that reach the third, fourth, and adult stages of development at 100 μg/ml
Medchemexpress LLC 1,3-propanediol-d6 | 284474-77-7 | MFCD01074057 | 99.3% | 82.13 g/mol | C3H2D6O2 | 5 MG
1,3-Propanediol-d6 is a deuterium-labeled analogue of 1,3-propanediol supplied as an isotope-labeled reagent for research applications. It is used as an internal standard or tracer in analytical techniques such as mass spectrometry and isotope tracing. The compound has formula C3H2D6O2, a molecular weight of 82.13 g/mol, and CAS 284474-77-7; follow recommended storage conditions to preserve isotopic integrity.
- Deuterium-labeled internal standard for analytical assays.
- Molecular formula C3H2D6O2 and molecular weight 82.13 g/mol.
- High isotopic and chemical purity (99.3%).
- Suitable for mass spectrometry and tracer experiments.
- Intended for research use only; not for human consumption.
- Recommended cold storage to maintain stability and isotopic composition.
Medchemexpress LLC Isovaleric acid-d9 | 344298-81-3 | 98.5% | 111.19 | 100 MG
Isovaleric acid-d9 is a deuterium-labeled form of isovaleric acid, a natural fatty acid. This compound is intended for research use only and serves as a valuable tool for quantitative analysis, acting as a tracer or an internal standard.
- Deuterium labeled.
- Natural fatty acid derivative.
- Suitable for use as a tracer in research.
- Functions as an internal standard for quantitative analysis.
- Compatible with NMR, GC-MS, and LC-MS analytical methods.
Medchemexpress LLC (R)-Neotame-d3 | 165450-17-9 | 381.48 | 1 MG
(R)-Neotame-d3 is the deuterium labeled Neotame. Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.