Isotopically Labeled Compounds
Medchemexpress LLC Linuron-d6 | 1219804-76-8 | 99.8% | 1 MG
Linuron-d6 is the deuterium labeled Linuron (HY-B1866). Linuron is a phenylurea herbicide used to control grass and weeds in agriculture and orchards. It acts as a photosystem II inhibitor and a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron exhibits reproductive toxicity in animals as an endocrine disruptor. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Acts as a photosystem II inhibitor
- Functions as a competitive androgen receptor (AR) antagonist
- Suitable for research use only
Medchemexpress LLC p-Toluic acid-d7 | 1219798-76-1 | MFCD06658857 | 99.7% | 10 MG
p-Toluic acid-d7 is the deuterium-labeled form of p-toluic acid (4-methylbenzoic acid), provided as a stable-isotope reference standard for analytical chemistry, metabolite tracing, and mass spectrometry applications. CAS 1219798-76-1; molecular weight 143.19 g/mol. Certificate of analysis reports high chemical purity and isotopic enrichment.
- High isotopic enrichment for accurate mass spectrometry.
- High chemical purity (~99.7% as reported by COA).
- Small 10 mg size suitable for method development and standards.
- Supplied with certificate of analysis and safety data sheet for traceability.
- Stable solid form, convenient for storage and handling.
Medchemexpress LLC Risperidone-d4 | 1020719-76-9 | 99.4% | 414.51 | 1 MG
Risperidone-d4 is the deuterium labeled Risperidone. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. This compound is for research use only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 16α-Hydroxyestrone | 566-76-7 | 99.7% | 286.37 | 1 MG
16α-Hydroxyestrone (16αOHE) is a major metabolite of Estradiol. It can be used for the research of metabolic diseases. Increasing levels of active estrogen metabolites, such as 16α-Hydroxyestrone and E3, are associated with increased bone mineral density.
- Endogenous metabolite
- Steroid structure
- Appearance: solid, white to off-white
- Solubility: ≥ 250 mg/mL in DMSO
Medchemexpress LLC Flurbiprofen-d5 | 215175-76-1 | MFCD27992097 | 99.8% | 249.29 g/mol | C15H8D5FO2 | 5 MG
Flurbiprofen-d5 is the deuterium-labeled isotopologue of flurbiprofen used as a stable isotope reference standard for analytical and mass spectrometry applications. It functions as an internal standard for quantitative LC-MS/MS assays and is provided in small, accurately weighed packages for method development and validation.
- Deuterated internal standard for LC-MS quantitation.
- High chemical purity: 99.8%.
- Molecular formula C15H8D5FO2 and molecular weight 249.29 g/mol.
- Supplied in small, calibrated quantities for accurate dosing.
- Suitable for method development, validation, and quantitative analysis.
Medchemexpress LLC p-Toluic acid-d7 | 1219798-76-1 | MFCD06658857 | 99.72% | C8HD7O2 | 25 MG
p-Toluic acid-d7 is the deuterium labeled p-Toluic acid. This substituted benzoic acid can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA) and p-tolunitrile. It is intended for research use only.
- Deuterium labeled compound
- Can be used as a tracer
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles in drug development
Medchemexpress LLC Flurbiprofen-d5 (dl-flurbiprofen-d5) | 215175-76-1 | 99.8% | 249.29 g·mol⁻¹ | C15H8D5FO2 | 1 MG
Flurbiprofen-d5 (dl-Flurbiprofen-d5) is a deuterium-labeled stable isotope analog of flurbiprofen used as an internal standard for quantitative mass spectrometry and other analytical applications.
- Purity 99.8%.
- Molecular weight 249.29 g·mol⁻¹.
- Chemical formula C15H8D5FO2.
- Isotope labeling d5 (five deuterium atoms).
- Available in small powder packs: 1 mg, 5 mg, 10 mg, 50 mg.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Intended for use as an analytical internal standard in mass spectrometry quantification.
Cambridge Isotope Laboratories SODIUM PROPIONATE (2-13C, 99%), 1 G, 83587-76-2
SODIUM PROPIONATE (2-13C, 99%), 1 G, 83587-76-2
Medchemexpress LLC 2'-Deoxyuridine-13C,15N2 | 369656-76-8 | 98.1% | 1 MG
2'-Deoxyuridine-13C,15N2 is the 13C and 15N labeled 2'-Deoxyuridine, a compound that can increase chromosome breakage and decrease thymidylate synthetase activity. It is also known as a precursor in the synthesis of Edoxudine.
- Can increase chromosome breakage.
- Results in decreased thymidylate synthetase activity.
- Precursor in the synthesis of Edoxudine.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Nirmatrelvir-d9 (PF-07321332-d9) | 2861202-76-6 | 99.9% | 508.58 | 1 MG
Nirmatrelvir-d9 (PF-07321332-d9) is the deuterium labeled Nirmatrelvir. It is intended for research use only and not for sale to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to impact the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
- Potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Inhibits SARS-CoV-2 3CLPRO, which is responsible for cleaving viral polyproteins and inhibiting viral replication.
Medchemexpress LLC N-valerylglycine-d2 | 3008541-76-9 | 95.0% | 161.20 g·mol⁻¹ | C7H11D2NO3 | 1 MG
A deuterium-labeled form of N-valerylglycine supplied as a 1 mg research standard for use as a stable isotope internal standard or tracer in analytical and metabolite studies. It supports improved quantitation and tracing in mass spectrometry workflows and is intended for research applications with appropriate storage to maintain stability.
- Stable isotope-labeled internal standard for mass spectrometry.
- Supplied as a 1 mg research-grade quantity.
- Purity 95.0%.
- Molecular formula C7H11D2NO3; molecular weight 161.20 g·mol⁻¹.
- Suitable for analytical method development and tracer studies.
- Storage recommended at low temperatures to preserve stability.
Medchemexpress LLC 3-Methoxytyramine-d4 hydrochloride | 1216788-76-9 | MFCD06658564 | 98.0% | 207.69 g/mol | C9H10D4ClNO2 | 1 MG
3-Methoxytyramine-d4 hydrochloride is the deuterium-labeled (d4) hydrochloride salt of 3-methoxytyramine (3-O-methyl dopamine). It is provided as a solid reference standard for use as an internal standard or tracer in quantitative analytical methods.
- Deuterium-labeled internal standard for quantitative analysis.
- Hydrochloride salt form for improved stability and handling.
- Suitable for LC-MS, GC-MS, and NMR applications.
- Available in small reference sizes (1 mg and 5 mg) for analytical workflows.
- Useful for accurate quantification and method validation in bioanalysis.
Medchemexpress LLC 6-((6,7-Bis(methoxy-d3)quinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamide | 2978508-76-6 | 99.5% | 399.43 | 1 MG
Fruquintinib-d6 is a deuterium-labeled analog of Fruquintinib, a selective and potent oral inhibitor of VEGFR-1, -2, and -3. This product is intended for research use only and has not been fully validated for medical applications. It is supplied as a white to off-white solid powder and should be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. This product is classified as hazardous with several precautionary statements.
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
- Stable under recommended storage conditions
Medchemexpress LLC 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-... | 1020719-76-9 | 99.4% | 414.51 | 50 MG
Risperidone-d4 is the deuterium-labeled version of Risperidone. Risperidone functions as a serotonin 5-HT2 receptor blocker, a P-Glycoprotein inhibitor, and a potent dopamine D2 receptor antagonist. It exhibits Ki values of 4.8 nM for the 5-HT2A receptor and 5.9 nM for the dopamine D2 receptor. This product is intended for research use only and is not sold to patients.
- Can be utilized as a tracer.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, primarily for quantitation as tracers during drug development.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Prednisolone-d7 | 367.49 | 1 MG
Prednisolone-d7 is a deuterium-labeled compound of Prednisolone, suitable for research applications. This product requires specific storage conditions to maintain its stability, with powder formulations stable for up to 3 years at -20°C and 2 years at 4°C. When in solvent, it remains stable for 6 months at -80°C and 1 month at -20°C.
- For research use only
- Not fully validated for medical applications
- Store powder at -20°C for up to 3 years
- Store powder at 4°C for up to 2 years
- Store in solvent at -80°C for up to 6 months
- Store in solvent at -20°C for up to 1 month