Amino Acids
Medchemexpress LLC Benzyl-PEG6-alcohol | 24342-68-5 | MFCD06797107 | 99.9% | 372.45 | C19H32O7 | 5 G
BnO-PEG6-OH is a benzyl-protected six-unit polyethylene glycol linker used as a non-cleavable spacer in antibody-drug conjugate (ADC) construction and as a PEG-based PROTAC linker. It provides a flexible, hydrophilic spacer for conjugation chemistry and is supplied at high purity for research applications.
- Non-cleavable six-unit PEG linker suitable for spacer applications.
- Applicable to ADC and PROTAC synthesis for flexible linkage.
- Molecular formula C19H32O7 and molecular weight 372.45.
- High purity suitable for research use.
- Available in multiple pack sizes, including 5 G.
Medchemexpress LLC Magnesium glycinate | 14783-68-7 | 98.0% | 5 G
Magnesium glycinate is the magnesium salt of glycine and functions as a nutrient supplement. It possesses satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed through chemical reactions between glycine and metal compounds. Magnesium, an essential mineral, plays a critical role in energy metabolism and helps maintain normal muscle function. It is considered an ideal nutrient supplement for the prophylaxis and treatment of metal deficiency.
- Nutrient supplement
- Satisfactory physico-chemical properties and bioactivities
- Formed through chemical reactions between glycine and metal compounds
- Magnesium plays a critical role in energy metabolism
- Assists in maintaining normal muscle function
- Ideal for prophylaxis and treatment of metal deficiency
Medchemexpress LLC D-Valine | 640-68-6 | 117.15 | 5 G
D-Valine is the enantiomer of L-Valine, one of 20 proteinogenic and essential amino acids. It is intended for research use only.
- Can be used to prevent the growth of fibroblasts in primary and secondary cell cultures of bovine artery endothelial cells
- Inhibits biofilm formation of P. gingivalis
Medchemexpress LLC L-Tryptophan-13C | 115709-68-7 | 205.22 | 5 MG
L-Tryptophan-13C is the 13C-labeled L-Tryptophan, an essential amino acid that is a precursor of serotonin, melatonin, and vitamin B3.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Cycloserine | 68-41-7 | 99.7% | C3H6N2O2 | 5 G
D-Cycloserine is an antibiotic that targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes and possesses blood-brain barrier permeability. It functions as a partial NMDA agonist, which can contribute to improved cognitive functions. This compound is also utilized in research concerning multidrug-resistant tuberculosis.
- Targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes
- Possesses blood-brain barrier permeability
- Functions as a partial NMDA agonist
- Contributes to improved cognitive functions
- Utilized in research concerning multidrug-resistant tuberculosis
Medchemexpress LLC Ly-2584702 tosylate salt | 1082949-68-5 | 99.5% | 617.62 | C28H27F4N7O3S | 500MG
LY-2584702 tosylate salt is a selective ATP-competitive inhibitor of p70S6K used for biochemical and cellular research into S6K signaling. It exhibits low-nanomolar potency in enzyme assays and reduces phosphorylation of S6 in cellular models. The compound is supplied as a light yellow solid and is typically prepared as a DMSO stock for in vitro studies.
- Selective ATP-competitive inhibitor of p70S6K; p70S6K IC50 4 nM, S6K1 enzyme assay IC50 2 nM.
- Inhibits cellular pS6 with effective concentrations around 100 nM; HCT116 pS6 IC50 0.1-0.24 μM.
- Observed off-target activity against MSK2 and RSK at higher concentrations (58-176 nM).
- High purity (99.5%) and light yellow solid appearance.
- Molecular formula C28H27F4N7O3S; molecular weight 617.62 g/mol.
- Stable when stored sealed away from moisture; in solution store at -80°C (1 year) or -20°C (6 months).
- Soluble in DMSO; prepare a 10 mM stock solution for in vitro assays.
Medchemexpress LLC Ly-2584702 tosylate | 1082949-68-5 | 99.5% | 617.6 g/mol | C28H27F4N7O3S | 250MG
LY-2584702 tosylate is the tosylate salt of LY-2584702, a selective, ATP-competitive inhibitor of p70 ribosomal S6 kinase (p70S6K/S6K1) used as a research tool in biochemical, cellular, and preclinical studies. Reported biochemical IC50 is 4 nM, S6K1 enzyme assay IC50 ≈ 2 nM, and cellular pS6 inhibition is observed at approximately 100 nM. High-purity material (CAS 1082949-68-5) is supplied for laboratory use.
- Selective ATP-competitive inhibitor of p70S6K.
- Biochemical potency: IC50 = 4 nM; S6K1 enzyme assay IC50 ≈ 2 nM.
- Demonstrated cellular pS6 inhibition at ~100 nM.
- Suitable for biochemical, cellular, and in vivo pharmacology studies.
- High purity (99.5%) and characterized by molecular weight 617.6 g/mol.
- Provided as the tosylate salt (CAS 1082949-68-5) for stability and handling.
Medchemexpress LLC BnO-PEG6-OH | 24342-68-5 | 99.9% | 372.45 g/mol | C19H32O7 | 250 MG
BnO-PEG6-OH is a benzyl-protected, hydroxyl-terminated polyethylene glycol linker containing six ethylene glycol units. It is supplied as a high-purity solid for use as a non-cleavable ADC linker and as a PEG-based linker in PROTAC synthesis.
- High purity (99.88%) for reliable conjugation chemistry.
- Six-unit PEG spacer provides flexibility and solubility.
- Benzyl-protected hydroxyl end enables selective functionalization.
- Available in multiple pack sizes including 250 mg for small-scale synthesis.
- Stable when stored at -20°C (solid) and in solution at -80°C.
Medchemexpress LLC Ly-2584702 tosylate salt | 1082949-68-5 | 99.5% | 617.62 | C28H27F4N7O3S | 100MG
LY-2584702 tosylate salt is the tosylate salt form of LY-2584702, a selective ATP-competitive inhibitor of p70S6K (S6K1) used in biochemical and cellular research to inhibit S6K signaling and downstream phosphorylation of the S6 ribosomal protein. It exhibits potent enzyme inhibition in the low nanomolar range and cellular activity in the submicromolar range, and is supplied in solid and solution formats for assay use.
- Selective ATP-competitive p70S6K inhibitor.
- Potent enzyme inhibition with low-nanomolar IC50 values.
- Demonstrated cellular inhibition of pS6 at submicromolar concentrations.
- Available in multiple solid sizes and a DMSO solution for assay preparation.
- High reported purity suitable for biochemical assays.
- Provided as tosylate salt to aid handling and formulation.
Medchemexpress LLC Ly-2584702 tosylate salt | 1082949-68-5 | 99.5% | 617.62 | C28H27F4N7O3S | 1G
LY-2584702 tosylate salt is an ATP-competitive inhibitor of p70S6K (S6K1) with nanomolar enzyme potency and reported cellular activity; intended for research use only.
- Selective ATP-competitive p70S6K inhibitor (enzyme IC50 = 4 nM).
- S6K1 enzyme assay IC50 = 2 nM.
- Inhibits phosphorylation of ribosomal protein S6 in cells (pS6 IC50 ≈ 0.1-0.24 μM).
- High purity: 99.5%.
- Molecular weight 617.62 g/mol.
- Storage: 4 °C sealed; in solvent -80 °C (1 year), -20 °C (6 months).
Medchemexpress LLC Ly-2584702 tosylate | 1082949-68-5 | MFCD29054739 | 99.5% | 617.62 g/mol | C28H27F4N7O3S | 25MG
LY-2584702 tosylate salt is a selective, ATP-competitive small-molecule inhibitor of p70S6K (S6K1) used in biochemical, cell-based, and in vivo preclinical research. It exhibits low-nanomolar enzyme potency and reduces phosphorylation of the S6 ribosomal protein in cells; it has demonstrated efficacy in xenograft models.
Medchemexpress LLC BnO-PEG6-OH | 24342-68-5 | MFCD06797107 | 99.9% | 372.45 g/mol | C19H32O7 | 500 MG
BnO-PEG6-OH is a non-cleavable six-unit polyethylene glycol (PEG) linker used for bioconjugation applications such as antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs). It provides a flexible spacer to modulate steric and pharmacokinetic properties during conjugation workflows.
- Non-cleavable six-unit PEG linker suitable for ADC and PROTAC synthesis.
- High purity for research-grade applications.
- Liquid, colorless to light yellow; density approximately 1.097 g/cm3.
- Available in multiple package sizes, including 500 mg.
- Stable when stored under recommended low-temperature conditions for extended periods.
Chemscene ChemScene | 5-Formylpicolinonitrile | 1G | CS-W018580 | 0.98 | 131747-68-7| MFCD12755972 | 132.12
ChemScene | 5-Formylpicolinonitrile | 1G | CS-W018580 | 0.98 | 131747-68-7| MFCD12755972 | 132.12
Medchemexpress LLC LY-2584702 tosylate salt | 1082949-68-5 | MFCD29054739 | 99.5% | 617.62 | C28H27F4N7O3S | 50MG
LY-2584702 tosylate salt is a small-molecule, ATP-competitive inhibitor of p70 ribosomal S6 kinase (p70S6K/S6K1) supplied as the tosylate salt for research use only. It exhibits low-nanomolar enzyme potency and cellular inhibition of S6 phosphorylation, making it suitable for studies of S6K signaling and related pathways.
- Selective ATP-competitive inhibition of p70S6K.
- Low-nanomolar enzyme potency (IC50 ≈ 2-4 nM).
- Cellular inhibition of S6 phosphorylation (IC50 ≈ 0.1-0.24 μM).
- Provided as a tosylate salt for improved handling.
- High reported purity (99.5%).
- Intended for laboratory research use only.
Medchemexpress LLC Hexaethylene glycol monobenzyl ether | 24342-68-5 | MFCD06797107 | 99.9% | 372.45 | C19H32O7 | 1 G
BnO-PEG6-OH (hexaethylene glycol monobenzyl ether) is a benzyl-protected, six-unit polyethylene glycol linker used as a short hydrophilic spacer in bioconjugation chemistry. It is commonly used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based linker in PROTAC design.
- Cas number: 24342-68-5.
- Purity: 99.9% (as supplied).
- Molecular formula: C19H32O7.
- Molecular weight: 372.45.
- Typical applications: ADC linker synthesis and PROTAC linker synthesis.
- Available pack sizes: 250 mg, 500 mg, 1 g, 5 g, 10 g, 25 g, 50 g.