Lipids and Lipid Derivatives
Medchemexpress LLC Estrone | 53-16-7 | 99.9% | 5 G
Estrone (E1) is a natural estrogenic hormone and the primary endogenous estrogen in postmenopausal women. It is produced by several tissues, particularly adipose tissue, through the aromatization of androstenedione.
- Natural estrogenic hormone and endogenous estrogen
- Produced in adipose tissue
- Targets estrogen receptor and ERR
- Relevant for endocrinology and cancer research
- Categorized as a natural product, inhibitor, or agonist
- Involved in vitamin D related and nuclear receptor pathways
- Involved in metabolic enzyme and protease pathways
- Stable as powder at -20°C for 3 years and 4°C for 2 years
- Stable in solvent at -80°C for 6 months and -20°C for 1 month
- Soluble in DMSO
Medchemexpress LLC Estrone | 53-16-7 | 100.0% | 1 G
Estrone (E1) is a natural estrogenic hormone and the main representative of endogenous estrogens. It is produced by several tissues, particularly adipose tissue, and results from the aromatization of androstenedione in fat cells. It is the main endogenous estrogen in postmenopausal women.
- Also known as E1 or Oestrone.
- Classified as a human endogenous metabolite.
- Appears as a white to off-white solid.
- Has a molecular weight of 270.37 and a chemical formula of C18H22O2.
- Insoluble in H2O (< 0.1 mg/mL) but soluble in DMSO (25 mg/mL).
- For research use only.
Medchemexpress LLC Estrone sulfate sodium | 438-67-5 | 99.8% | 372.41 | 1 ML
Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone and Estradiol. It is a substrate of the OATP1B3 transporter and is applicable to breast cancer-related research. It stimulates the growth of nitrosomethylurea-induced mammary tumors and colony formation of dispersed nitrosomethylurea mammary cells.
- Inactive endogenous estrogen
- Converted to estrone and estradiol
- Substrate of OATP1B3 transporter
- Stimulates mammary tumor growth
- Applicable to breast cancer research
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 99.99% | C18H23NO4S | 1 MG
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. It can be used for cancer research.
- Potent steroid sulfatase (STS) inhibitor
- Demonstrates inhibitory activity in placental microsomes (P.M.) and MCF-7 cells
- Applicable for cancer research
Medchemexpress LLC Estrone 3-glucuronide sodium | 15087-01-1 | 98.3% | 468.47 | 1 MG
Estrone 3-glucuronide sodium is a metabolite of 17-Estradiol. It is used as a standard to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs) and is the reference standard used in assays that measure urinary E1C, a key marker for tracking the transition to the luteal phase.
- Estimates estrone conjugate (E1Cs) from urine samples
- Used in enzyme immunoassays (EIAs)
- Reference standard in assays measuring urinary E1C
- Key marker for tracking the transition to the luteal phase
- Useful in urogenital, urologic, and endocrinology research
Medchemexpress LLC Estrone 3-methyl ether | 1624-62-0 | 97.38% | C19H24O2 | 5 MG
Estrone 3-methyl ether is a synthetic intermediate used in the synthesis of estrogen receptor modulators.
- Used in the synthesis of estrogen receptor modulators
- Molecular weight: 284.39
- Molecular formula: C19H24O2
- CAS number: 1624-62-0
- Purity: 97.38%
- Appearance: Solid, white to off-white
- Storage (Powder): -20°C for 3 years; 4°C for 2 years
- Storage (In solvent): -80°C for 6 months; -20°C for 1 month
Cayman Chemical Estrone Steroid Hormones
A primary, naturally-occurring estrogen; serum concentrations in premenopausal women fluctuate according to the menstrual cycle; becomes the most predominant estrogen in postmenopausal women; binding affinities to ERα and ERβ are ~60% and ~37% relative to estradiol
Medchemexpress LLC Estrone-d4 | 53866-34-5 | 99.5% | 5 MG
Estrone-d4 is a deuterium-labeled version of Estrone (E1), a naturally occurring estrogenic hormone. It represents a primary endogenous estrogen, synthesized in various tissues, particularly adipose tissue, through the aromatization of androstenedione in fat cells.
- Deuterium labeled: it is labeled with deuterium, a stable heavy isotope of hydrogen.
- Tracer: can be utilized as a tracer in research applications.
- Internal standard: suitable for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Pharmacokinetic and metabolic studies: deuteration can influence the pharmacokinetic and metabolic profiles of compounds.
Medchemexpress LLC Estrone sulfate (sodium) | 438-67-5 | 99.8% | 372.41 | 25 MG
Estrone sulfate sodium is an inactive endogenous estrogen. It can be converted into Estrone and Estradiol and is a substrate of the OATP1B3 transporter. This compound stimulates the growth of nitrosomethylurea-induced mammary tumors and colony formation of dispersed nitrosomethylurea mammary cells, with conversion to Estrone and Estradiol occurring both in vivo and in vitro.
- Can be converted into Estrone and Estradiol.
- Substrate of the OATP1B3 transporter.
- Stimulates mammary tumor growth in ovariectomized rats.
- Applicable to breast cancer-related research.
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 1 MG
Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 1 MG
Cayman Chemical 6-MethylmercaptopurIn-d3 10mg
An internal standard for the quantification of 6-MMP by GC- or LC-MS