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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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2'-Deoxycytidine-5'-monophosphate (5'-dCMP) is an endogenous metabolite and a deoxynucleotide building block of DNA. It serves as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, which supports DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block of DNA
Supports DNA biosynthesis
Substrate for UMP/CMP kinase
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2'-Deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium is a 13C and 15N-labeled version of 2'-Deoxycytidine-5'-monophosphoric acid, which is an endogenous metabolite.
13C and 15N-labeled compound.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Endogenous metabolite.
Stable heavy isotopes of hydrogen, carbon, and other elements can be incorporated into drug molecules for quantitation during drug development.
Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis.
Used as an analytical standard.
Supports DNA biosynthesis.
Suitable for qualitative research experiments.
Suitable for quantitative research experiments.
Suitable for methodological research experiments in HPLC, GC, and MS.
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KTX-951 is an orally active PROTAC degrader targeting IRAK4 and IMiD (Ikaros/Aiolos) substrates. It demonstrates potent DC50s against IRAK4, Ikaros, and Aiolos, and exhibits antitumor activity with an IC50 of 35 nM for OCl-Ly10 CTG.
Orally active PROTAC degrader
Targets IRAK4 and IMiD substrates (Ikaros/Aiolos)
Potent DC50s for IRAK4, Ikaros, and Aiolos
Exhibits antitumor activity
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2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
Brain-penetrant pyrimidines nucleotide
Associated with nervous system diseases
Increases chromosome breakage
Decreases thymidylate synthetase activity
Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
Promising for Alzheimer's disease (AD) research
Appearance: Solid
Color: White to off-white
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block of DNA
Can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite and a deoxynucleotide building block of DNA. It acts as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
Endogenous metabolite
Deoxynucleotide building block for DNA
Substrate for UMP/CMP kinase
Supports DNA biosynthesis
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More