Sugar acids and derivatives
Medchemexpress LLC Integrin alpha V bet 50ug
Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Integrin alpha X bet 10ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Medchemexpress LLC Bet bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 g/mol | C24H20ClN5O2 | 100 MG
BET bromodomain inhibitor is a small-molecule research compound that selectively inhibits BET family bromodomains, including BRD4, with reported biochemical potency (BRD4(1) IC50 = 14 nM). It is supplied as a solid (white to off-white) with high purity for preclinical laboratory use.
- Potent BRD4 inhibitor (IC50 = 14 nM).
- High purity (~99.5%).
- Solid, white to off-white powder.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small research quantities, including 100 MG packaging.
![Medchemexpress LLC [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P | 96736-12-8 | MFCD00076802 | 98.5% | 1516.83 Da | C79H109N19O12 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248571.png-250.jpg)
Medchemexpress LLC [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P | 96736-12-8 | MFCD00076802 | 98.5% | 1516.83 Da | C79H109N19O12 | 10 MG
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is a synthetic modified decapeptide derived from Substance P and supplied as a lyophilized powder for laboratory research. It is used to probe neuropeptide and chemokine receptor signaling, acting as a biased agonist that modulates G12 and JNK pathways and influences neutrophil migration and Ca2+ mobilization.
- Modified decapeptide sequence: {d-Arg}-Pro-Lys-Pro-{d-Phe}-Gln-{d-Trp}-Phe-{d-Trp}-Leu-Leu-NH2
- High purity (98.48%)
- Molecular weight 1516.83 Da
- Chemical formula C79H109N19O12
- Supplied as lyophilized powder for research use only
- Recommended storage: powder at -80°C for long-term stability
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
Medchemexpress LLC Bet-bay 002 | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MM 1ML
BET-BAY 002 is a small-molecule inhibitor of BET family bromodomains used for epigenetic and oncology research. It has demonstrated efficacy in multiple myeloma models and is supplied in solution and solid forms suitable for biochemical and cellular assays.
- Supplied as a 10 mM solution in DMSO (1 mL) and as solid quantities.
- High purity (99.8%).
- Molecular weight 403.86 g/mol and formula C22H18ClN5O.
- Soluble in DMSO for straightforward stock preparation.
- Intended for research use in BET bromodomain inhibition and related assays.
![Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237008.png-250.jpg)
Medchemexpress LLC 2-((6-(4-chlorophenyl)-1-methyl-4H-triazolo[4,3-a]azepin-4-yl)methyl)-5-methyl-1,3,4-oxadiazole | 1588521-78-1 | 99.8% | 403.86 g/mol | C22H18ClN5O | 10MG
BET-BAY 002 is a research-grade small-molecule BET bromodomain inhibitor used in epigenetic and oncology research. It is supplied as a white to off-white solid (CAS 1588521-78-1) with a molecular weight of 403.86 g/mol and reported high purity for reliable experimental use. The compound dissolves readily in DMSO and has recommended storage conditions for long-term stability.
Medchemexpress LLC 5-bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 98.0% | 444.59 g/mol | C14H12BrClNNaO7 | 10 MG
X-Gluc sodium is the sodium salt of 5-bromo-4-chloro-3-indolyl β-D-glucuronide, a chromogenic substrate used to detect β-glucuronidase (GUS) activity. It reacts with GUS to produce an intense blue color and is commonly used in microbiology and molecular biology assays.
- Chromogenic substrate for β-glucuronidase detection
- Produces intense blue color upon enzymatic hydrolysis
- Suitable for bacterial contamination testing and GUS reporter assays
- High purity (98.0%) for reliable experimental results
- Sodium salt form improves handling and aqueous solubility
Sigma Aldrich Fine Chemicals Biosciences Polygalacturonic acid | 25990-10-7 | MFCD00131972 | 25g
Polygalacturonic acid | Purity: 85% | 25990-10-7 | MFCD00131972 | 25g
Medchemexpress LLC D-Dimannuronic acid sodium | 10 MG
D-Dimannuronic acid sodium is an alginate extract derived from brown algae. This compound is primarily used in research to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides. It is intended for research use only.
- Derived from brown algae
- Used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides
- For research use only
- Purity of 99.94%
- Molecular weight of 392.25
- Molecular formula is C12H17NaO13
- Appears as a white to off-white solid
- Soluble in H2O at 125 mg/mL (318.67 mM), requires ultrasonic treatment
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097080.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 25mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097081.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 5mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
AdipoGen 3OH-C10-L-HSL
Chemical. CAS 192883-12-8. Formula C14H25NO4. MW 271.35. Synthetic. N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Medchemexpress LLC Integrin alpha V bet 50ug | 50ug
Integrin alpha V beta 3 (ITGAV ITGB3) functions as a receptor for CD40LG enhancing Lilrb4a inhibitory effects on mast cell activation It suppresses marginal zone B cell antibody production through Lilrb4a interaction ITGAV ITGB3 forming a heterodimer with ITGAV interacts with ligands such as RAB25 CIB1 FBLN5 and more It also forms a complex with PTPRZ1 and PTN stimulating endothelial cell migration Integrin alpha V beta 6 Protein Mouse (HEK293 His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Mouse (HEK293 His) has molecular weight of 90-140 kDa