Sugar acids and derivatives
Medchemexpress LLC D-Biotinol 25mg
D-Biotinol is the nutrition of Lactobacillus arabinosus L casei or Saccharomyces cerevisiae D-Biotinol replaces the D-biotin (HY-B0511) in saving egg white induced biotin deficiency in rats D-Biotinol is orally active and displays to be converted to biotin by rats[1]
Medchemexpress LLC β-D-glucopyranosiduronic acid p-nitrophenyl carbonate derivative | 894095-98-8 | 99.6% | 913.83 g/mol | C45H43N3O18 | 1 G
β-D-glucuronide-pNP-carbonate is a glucuronide-cleavable carbonate linker used to attach payloads to antibodies for research-scale antibody-drug conjugate (ADC) synthesis. It is supplied as a purified small-molecule reagent for linker-payload assembly and analytical characterization.
- Cleavable glucuronide-based linker responsive to glycosidase cleavage.
- Reported purity around 99.6%.
- Molecular formula C45H43N3O18; molecular weight 913.83 g/mol.
- Available in small-scale packaging including 1 G; larger quantities available on request.
- Supporting documents include datasheet, certificate of analysis, and safety data sheet.
Matrix Scientific (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)-tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, MFCD00061613, 1g
Molecular Formula C13H17BrO9, Purity 95+%, Molecular Weight 397.18, Melting Point 106-107°
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | 99.8% | 284.26 g/mol | C9H20N2O8 | 10 MG
Tetrahydrouridine dihydrate is the dihydrated form of tetrahydrouridine, a potent competitive inhibitor of cytidine deaminase (CDA). Supplied as a white to off-white solid for research use, it is used to inhibit cytidine deamination, support studies of DNA/RNA synthesis pathways, and sensitize carcinoma cells to cytidine analog chemotherapeutics such as gemcitabine.
- Potent competitive inhibitor of cytidine deaminase (CDA).
- High purity (≈99.8%) suitable for research applications.
- Dihydrate form; molecular weight 284.26 g/mol.
- White to off-white solid, convenient for analytical and biological assays.
- Stable when stored as powder at -20°C (long-term storage).
- Available in small assay sizes for laboratory use.
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 500 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a water-soluble blue fluorescent coumarin fluorophore when cleaved
- Detectable using a fluoroenzymeter or fluorometer
- White to off-white solid
- Molecular weight of 338.31
- Purity of 99.06%
- Excitation at 390 nm
- Emission at 480 nm
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 100 MG
Sodium zirconium cyclosilicate is an inorganic, microporous zirconium silicate compound used as a selective cation-exchange reagent that binds potassium ions for biomedical and kidney disease research.
- Selectively binds potassium ions for removal in vitro or preclinical studies.
- Inorganic, non-absorbed microporous structure suitable for research applications.
- Available in multiple small-scale sizes for laboratory use.
- Supplied as a solid reagent with specified purity for experimental reproducibility.
![Medchemexpress LLC 3,4,8,9-tetrahydroxy-6H-benzo[c]chromen-6-one | 131086-98-1 | MFCD00954508 | 99.7% | C13H8O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260269.png-250.jpg)
Medchemexpress LLC 3,4,8,9-tetrahydroxy-6H-benzo[c]chromen-6-one | 131086-98-1 | MFCD00954508 | 99.7% | C13H8O6 | 10MG
Urolithin D (3,4,8,9-tetrahydroxy-6H-benzo[c]chromen-6-one; CAS 131086-98-1) is a colonic metabolite of ellagitannins used in biochemical and cell-based research. It acts as a competitive, reversible antagonist of EphA receptors, displays antioxidant activity, and modulates lipid metabolism and fatty acid oxidation. Offered as high-purity solid and DMSO solution formats for research use.
- High purity (>99.7%) suitable for analytical and biological assays.
- Molecular formula C13H8O6 and molecular weight 260.20 g/mol.
- Acts as a competitive, reversible antagonist of EphA receptors.
- Exhibits antioxidant activity and supports studies of oxidative stress.
- Modulates lipid metabolism and promotes fatty acid oxidation.
- Useful for tumor, metabolic, and inflammatory disease research.
- Available as solid and DMSO solution formats for convenient handling.
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 25 MG
BET-IN-14 is an orally active pan BET inhibitor with an IC50 of 5.35 nM. It exhibits anti-cancer activity. In vitro studies show that BET-IN-14 (Compound 171) has anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM), particularly in MM.1S, Ty-82, MV-4-11, and KG-1 cells. In vivo, BET-IN-14 (50 and 100 mg/kg, p.o., qd) inhibits tumor growth in MV-4-11 xenograft models by 60.36%.
- Orally active pan BET inhibitor with high potency (IC50 of 5.35 nM)
- Displays anti-tumor activity against various cancer cell lines (average IC50: 174.7 nM)
- Effective in MM.1S, Ty-82, MV-4-11, and KG-1 cells
- Inhibits tumor growth in MV-4-11 xenograft models by over 60% at tested dosages
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 5 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. It promotes the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) through induction of EMT process at concentrations of 0.5-1 mM over 24 hours.
- Critical precursor for essential glycoconjugates
- Promotes migration of liver cancer cells
- Induces EMT process in liver cancer cells
- Decreases E-cadherin and increases vimentin levels in Huh7 and SNU449 cells
Medchemexpress LLC D-Glucuronic acid | 99.9% | 240.09 g·mol⁻¹ | 13C6H11NaO8 | 10 MG
13C6-labeled D-glucuronic acid sodium salt monohydrate provided as a stable-isotope internal standard for metabolomics and biochemical research. The material is the sodium salt monohydrate of D-glucuronic acid, isotopically labeled on all six carbons (13C6), and supplied as a high-purity dry solid.
- 13C6 isotopic labeling for tracer and internal standard use.
- High purity (HPLC) - 99.9%.
- Molecular weight 240.09 g·mol⁻¹ and formula 13C6H11NaO8.
- Suitable for LC-MS and metabolomics workflows as a standard or tracer.
- Supplied as a stable dry solid for controlled storage.
Medchemexpress LLC 4-methylumbelliferyl α-L-arabinofuranoside | 77471-44-4 | MFCD00057308 | 99.9% | 308.28 | C15H16O7 | 5 MG
4-Methylumbelliferyl α-L-arabinofuranoside is a fluorogenic glycosidase substrate used to measure α-L-arabinofuranosidase activity. Enzymatic hydrolysis releases fluorescent 4-methylumbelliferone, enabling sensitive fluorometric assays in biochemical and enzymology workflows. For research use only.
- Fluorogenic substrate for α-L-arabinofuranosidase assays.
- Produces 4-methylumbelliferone for sensitive fluorometric detection.
- High purity (99.93%) to minimize background signal.
- Molecular weight 308.28 and formula C15H16O7.
- Soluble in DMSO at ≥ 50 mg/mL.
- White to off-white solid with recommended cold storage for stability.
- Supplied in small research pack sizes suitable for assay development.
Medchemexpress LLC D-Psicose-d | 53685-24-8 | 99.9% | 181.16 | 25 MG
D-Psicose-d is a deuterium-labeled D-Psicose, an orally active rare sugar. It inhibits p38-MAPK phosphorylation and MCP-1 expression, and also inhibits the AGEs/RAGE/NF-κB pathway. It protects pancreatic β-islets, and improves hyperglycemia and high-fat diet-induced non-alcoholic fatty liver disease.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
- For research use only
Medchemexpress LLC 4-methylumbelliferyl β-d-glucopyranoside | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 1G
4-Methylumbelliferyl β-D-Glucopyranoside is a fluorogenic β-D-glucoside substrate used to measure β-glucosidase activity. Enzymatic cleavage releases 4-methylumbelliferone (4-MU), a highly fluorescent reporter (emission 445-454 nm); excitation maxima are pH-dependent (330, 370, 385 nm at pH 4.6, 7.4, 10.4). The product is supplied as a solid and as a 10 mM solution in DMSO for convenient assay setup.
- Fluorogenic substrate for β-glucosidase assays.
- Releases 4-methylumbelliferone for sensitive fluorescence detection.
- High reported purity (99.87%).
- Available as solid and 10 mM solution in DMSO.
- Suitable for biochemical and cell-based enzyme activity assays.
- Molecular weight 338.31 g/mol; formula C16H18O8.
- Pack sizes suitable for assay workflows, including 1 g solid options.
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier function
- Modulates gut microbiota
- Increases beneficial bacterial populations
- Suppresses harmful bacterial populations