Drug Standards
Medchemexpress LLC Naphazoline nitrate | 5144-52-5 | 99.1% | 273.29 | 100 MG
Naphazoline nitrate is an α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also reduces levels of inflammatory factors and can be used for non-bacterial conjunctivitis research.
- Targets α-adrenergic receptors
- Helps manage vascular issues
- Decreases levels of TNF-α, IL-1β, IL-6, IFN-γ, IL-4, IgE, GMCSF, and NGF
- Applicable for non-bacterial conjunctivitis research
- Solid, white to off-white appearance
- Solubility: 100 mg/mL in DMSO
Medchemexpress LLC Gemcitabine monophosphate disodium | 1638288-31-9 | 387.14 | 10 MM * 1 ML
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine. It has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles.
- Active intermediate of Gemcitabine.
- Synergistic anti-cancer effect.
- Can be delivered via nanoparticles.
- In vivo studies show it induces tumor cell apoptosis (30-40%), reduces tumor cell proliferation by 8 times, significantly reduces tumor microvessel density (MVD), and inhibits tumor mitosis in subcutaneous and orthotopic xenograft mouse models of non-small cell lung cancer.
Medchemexpress LLC Naphazoline | 835-31-4 | MFCD00066737 | 99.7% | 210.27 | 25 MG
Naphazoline is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also reduces the levels of inflammatory factors (TNF-α, IL-1β, and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. It can be used for non-bacterial conjunctivitis research.
- Reduces vascular hyperpermeability
- Promotes vasoconstriction
- Reduces inflammatory factors and cytokines
- Used for non-bacterial conjunctivitis research
Medchemexpress LLC Naphazoline hydrochloride | 550-99-2 | 99.4% | 10 MM * 1 ML
Naphazoline hydrochloride is a potent α-adrenergic receptor agonist that reduces vascular hyperpermeability and promotes vasoconstriction. It also decreases the levels of inflammatory factors (TNF-α, IL-1β, and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. This compound can be used for non-bacterial conjunctivitis research and is intended for research use only, not sold to patients.
- Potent α-adrenergic receptor agonist
- Reduces vascular hyperpermeability and promotes vasoconstriction
- Decreases inflammatory factors (TNF-α, IL-1β, and IL-6)
- Decreases cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF
- Suitable for non-bacterial conjunctivitis research
Medchemexpress LLC Isradipine | 75695-93-1 | 5 MG
Isradipine is an orally active, blood-brain barrier permeable L-type calcium channel blocker. It functions as a potent peripheral vasodilator and is a dihydropyridine calcium antagonist with selective effects on the heart and peripheral circulation. Isradipine is considered a potentially viable neuroprotective agent for Parkinson's disease.
- Orally active
- Blood-brain barrier permeable
- L-type calcium channel blocker
- Potent peripheral vasodilator
- Dihydropyridine calcium antagonist with selective effects on the heart and peripheral circulation
- Potentially viable neuroprotective agent for Parkinson's disease
Medchemexpress LLC Ibiglustat (succinate) | 1629063-80-4 | 99.7% | 507.57 | 50 MG
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. It can be utilized for research related to Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
- Orally active.
- Brain-penetrant glucosylceramide synthase (GCS) inhibitor.
- Can be used for research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
Medchemexpress LLC Folic acid disodium | 29704-76-5 | 98.6% | 485.36 | 50 MG
Folic acid disodium, also known as Vitamin B9 disodium or Vitamin M disodium, is an orally active disodium salt form of Folic acid. It functions as a cofactor in single-carbon transfer reactions and provides protective effects against neural tube defects, ischemic events, and certain cancers. Conversely, an overload of folic acid disodium can impair brain development during embryogenesis and promote the growth of precancerous altered cells, and a deficiency can lead to megaloblastic anemia.
- Orally active disodium salt form of folic acid.
- Acts as a cofactor in single-carbon transfer reactions.
- Offers protective effects against neural tube defects, ischemic events, and certain cancers.
- High purity of 98.56%.
- Molecular weight of 485.36.
Medchemexpress LLC Folic acid (disodium) | 29704-76-5 | 98.6% | 485.36 | 25 MG
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid with an intrinsic dissolution rate (IDR) of 4.96·10^5 g/s. It serves as a cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia.
- Orally active disodium salt form of folic acid.
- Serves as cofactor in single-carbon transfer reactions.
- Exhibits protective effects against neural tube defects, ischemic events, and cancer.
- Deficiency leads to megaloblastic anemia.
Medchemexpress LLC Itacitinib adipate | 1334302-63-4 | 99.2% | 699.66 | 1 ML
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis.
- Orally bioavailable and selective JAK1 inhibitor.
- Tested for efficacy and safety in a phase II trial in myelofibrosis.
- For research use only.
Medchemexpress LLC Actin Related Protein 2 Antibody (YA2725) | 10 UL
The Actin Related Protein 2 Antibody (YA2725) is a rabbit-derived antibody designed for research applications. It shows reactivity with human, mouse, and rat samples and is suitable for Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF) techniques.
- Host: Rabbit
- Reactivity: Human, mouse, rat
- Clonality: YA2725
- Molecular weight: 45 kDa
- Concentration: 0.3 mg/mL
- Applications: Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)
- Storage: Store at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Medchemexpress LLC Actin Related Protein 2 Antibody (YA2725) | 100 UL
This Actin Related Protein 2 Antibody (YA2725) is a rabbit-host antibody designed for various research applications. It reacts with human, mouse, and rat samples, making it suitable for a broad range of studies.
- Host: Rabbit
- Reactivity: Human, mouse, rat
- Applications: WB (1:500-1:1000), ICC/IF (1:50-1:200)
- Molecular weight: Predicted and observed at 45 kDa
- Concentration: 0.3 mg/mL
- Formulation: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Storage & Stability: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Shipping: With blue ice
Medchemexpress LLC Oxibendazole | 20559-55-1 | 99.6% | 25 MG
Oxibendazole is an effective benzimidazole anthelmintic that combats nematode infections. It has demonstrated the ability to induce apoptosis and exhibits both anti-cancer and anti-inflammation activities.
- Induces apoptosis
- Active against nematode infections
- Exhibits anti-cancer activities
- Possesses anti-inflammation properties
- Downregulates phosphorylation of ERK1/2, P90RSK, and S6
- Upregulates expression of phosphorylated JNK, AKT, and P70S6K
Medchemexpress LLC Glipizide (Standard) | 29094-61-9 | 99.7% | 25 MG
Glipizide (Standard) is an analytical standard of Glipizide, intended for research and analytical applications. It is a potent, orally active sulfonylurea class anti-diabetic agent used for type 2 diabetes mellitus research.
- Potent, orally active sulfonylurea class anti-diabetic agent
- Used for type 2 diabetes mellitus research
- Acts by partially blocking ATP-sensitive potassium (KATP) channels
- Suitable for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- IC50: 6.4 nM ATP-sensitive potassium (KATP) channels in primary mouse pancreatic β cells
Medchemexpress LLC Clopidogrel-related Compound B (hydrochloride) | 144750-52-7 | 99.7% | 358.28 | 50 MG
Clopidogrel-related Compound B hydrochloride is an impurity of Clopidogrel. It is a solid with a white to yellow appearance, typically used for laboratory research.
- High purity at 99.67%
- Molecular weight of 358.28
- Chemical formula is C16H17Cl2NO2S
- Identified by CAS number 144750-52-7
Medchemexpress LLC Naphazoline hydrochloride | 550-99-2 | 99.4% | 5 G
Naphazoline hydrochloride is a potent α-adrenergic receptor agonist. It reduces vascular hyperpermeability and promotes vasoconstriction. This compound also decreases the levels of inflammatory factors (TNF-α, IL-1β, IL-6), cytokines (IFN-γ, IL-4), IgE, GMCSF, and NGF. It is used in research for non-bacterial conjunctivitis.
- Reduces vascular hyperpermeability
- Promotes vasoconstriction
- Decreases inflammatory factors (TNF-α, IL-1β, IL-6)
- Decreases cytokines (IFN-γ, IL-4)
- Decreases IgE, GMCSF, and NGF levels
- Used in research for non-bacterial conjunctivitis