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Filtered Search Results
Medchemexpress LLC Cefozopran hydrochloride | 113981-44-5 | MFCD00944908 | >95.0% | 1 ML
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Cefozopran hydrochloride (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin antibiotic. This antibiotic demonstrates a broad spectrum of antibacterial activity, effectively inhibiting most gram-negative and gram-positive organisms.
- Semi-synthetic
- Parenteral, fourth-generation cephalosporin
- Broad-spectrum antibacterial activity
- Effectively inhibits most gram-negative organisms
- Effectively inhibits most gram-positive organisms
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eMolecules 172479-50-4 | (R)-2-tert-Butoxycarbonylamino-3-methoxy-3-oxopropylzinc iodide, 0.50 M in THF | Synthonix394.510 | C9H16INO4Zn | 0.000 | [I-].COC(=O)[C@H](C[Zn+])NC(=O)OC(C)(C)C | 100ml | 532652607
(R)-2-tert-Butoxycarbonylamino-3-methoxy-3-oxopropylzinc iodide, 0.50 M in THF | Synthonix | 172479-50-4394.510 | C9H16INO4Zn | 0.000 | [I-].COC(=O)[C@H](C[Zn+])NC(=O)OC(C)(C)C | 100ml | 532652607
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Medchemexpress LLC Buflomedil hydrochloride | 35543-24-9 | 99.8% | 1 ML
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Buflomedil hydrochloride is a vasodilator agent and an orally active α1A-adrenoceptor antagonist. Its Kis are 4.06 μM for α1A-AR and 6.84 μM for α1B-AR. It can be used for the study of peripheral circulatory disorders.
- Vasodilator agent
- Orally active α1A-adrenoceptor antagonist
- Used for studying peripheral circulatory disorders
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Medchemexpress LLC Buflomedil hydrochloride | 35543-24-9 | 99.8% | 5 G
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Buflomedil hydrochloride is a vasodilator agent that acts as an orally active α1A-adrenoceptor antagonist. It is utilized in the study of peripheral circulatory disorders and appears as a white to off-white solid.
- Acts as an orally active α1A-adrenoceptor antagonist
- Used for the study of peripheral circulatory disorders
- Has a purity of 99.8%
- Soluble in water and DMSO
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Medchemexpress LLC PRMT5-IN-1 hydrochloride | 99.5% | 455.29 | 1 MG
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PRMT5 IN-1 hydrochloride (compound 9) is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor. It functions as a hemiaminal and can be converted to aldehydes, reacting with C449 to form covalent adducts under physiological conditions. This compound inhibits cellular sDMA expression and cell proliferation in Granta-519 cells.
- Potent, selective PRMT5 inhibitor
- IC50 of 11 nM for PRMT5/MEP50
- Inhibits cellular sDMA expression with an IC50 of 0.012 μM
- Inhibits cell proliferation in Granta-519 cells with an IC50 of 0.06 μM
- Forms covalent adducts with C449
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Medchemexpress LLC Tamsulosin (hydrochloride) | 106463-17-6 | 99.8% | 25 MG
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Tamsulosin hydrochloride is an orally active antagonist of the α1-adrenergic receptor. It induces apoptosis and is used for research related to prostatic hyperplasia. It also attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models.
- Orally active α1-adrenergic receptor antagonist
- Induces apoptosis
- Used for research of prostatic hyperplasia
- Attenuates abdominal aortic aneurysm growth
- Inhibits inflammation in animal models
- Stable under recommended storage conditions
- White to off-white solid appearance
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Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | MFCD00150062 | 99.2% | 262.73 | 25 MG
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Neocuproine hydrochloride monohydrate can be used to prepare complex solutions for studying antioxidant capacity determination in biological samples based on copper reduction complexes.
- Appearance: solid
- Color: off-white to light yellow
- Handling instructions: store at room temperature, keep dry and cool. In solvent: -80°C 1 year, -20°C 6 months.
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Medchemexpress LLC Adiphenine hydrochloride | 50-42-0 | 99.1% | 500 MG
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Adiphenine hydrochloride is a non-competitive inhibitor of the nicotinic acetylcholine receptor (nAChR). It exhibits anticonvulsant effects and has specific IC50 values for various nAChR subtypes including α1, α3β4, α4β2, and α4β4. In vivo, it prevents hindleg tonic-extensor components of maximal electroshock seizures (MES) in mice.
- Non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR)
- Exhibits anticonvulsant effects
- Specific IC50 values for α1, α3β4, α4β2, and α4β4 nAChR subtypes
- Prevents hindleg tonic-extensor components of maximal electroshock seizures (MES) in mice
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Medchemexpress LLC Tizanidine (hydrochloride) | 64461-82-1 | 99.93 % | 1 ML
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Tizanidine hydrochloride is a skeletal muscle relaxant that acts as an orally effective central α2-adrenoceptor agonist. It primarily relaxes muscles by inhibiting the release of excitatory amino acids from spinal cord interneurons. Additionally, it exhibits anti-injury activity, can inhibit gastrointestinal (GI) transport, and has been shown to inhibit proliferation, migration, and invasion of lung cancer cells, inducing cell apoptosis. This compound is used to treat spasticity from conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
- Skeletal muscle relaxant
- Central α2-adrenoceptor agonist
- Inhibits excitatory amino acid release
- Exhibits anti-injury activity
- Inhibits gastrointestinal (GI) transport
- Inhibits lung cancer cell proliferation, migration, and invasion
- Induces cell apoptosis
- Treats spasticity from multiple sclerosis, stroke, and spinal cord injury
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Medchemexpress LLC Cephalexin hydrochloride | 59695-59-9 | 99.8% | 1 ML
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Cephalexin hydrochloride is a potent, orally active, new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. It demonstrates antibacterial activity against a wide variety of gram-positive and gram-negative bacteria by targeting penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. It is utilized in research for conditions such as pneumonia, strep throat, and bacterial endocarditis.
- Disrupts polymer peptidoglycan (PG) biogenesis
- Inhibits a broad spectrum of gram-positive and gram-negative organisms
- Has antibacterial activity in male Swiss-Webster mice with infected bacterial
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Medchemexpress LLC Irinotecan hydrochloride trihydrate | 136572-09-3 | 99.9% | 677.18 | 100 MG
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Irinotecan hydrochloride trihydrate is a topoisomerase I inhibitor with antitumor activity, used to treat colon and rectal cancer. It is for research use only and has been shown to inhibit the growth of various cancer cell lines, such as LoVo and HT-29.
- Inhibits topoisomerase I
- Demonstrates antitumor activity
- Suppresses proliferation of human umbilical vein endothelial cells
- Available for research use only
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Medchemexpress LLC Buflomedil (hydrochloride) | 35543-24-9 | 99.8% | 500 MG
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Buflomedil hydrochloride is a vasodilator agent and an orally active α1A-adrenoceptor antagonist. It is characterized by its Ki values of 4.06 μM for α1A-AR and 6.84 μM for α1B-AR. This compound is primarily used for the study of peripheral circulatory disorders.
- Vasodilator agent
- Orally active α1A-adrenoceptor antagonist
- Useful for studying peripheral circulatory disorders
- High purity of 99.8%
- Appears as a white to off-white solid
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Medchemexpress LLC Melevodopa hydrochloride | 1421-65-4 | 99.8% | 247.68 | 5 G
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Melevodopa hydrochloride is an effervescent Levodopa prodrug. Levodopa is an orally active metabolic precursor of the neurotransmitter dopamine and has anti-allodynic effects and potential for treating Parkinson's disease.
- Effervescent prodrug of Levodopa
- Metabolic precursor of dopamine
- Anti-allodynic effects
- Potential for Parkinson's disease treatment
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Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 1 G
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Octopamine hydrochloride is a biogenic monoamine structurally related to noradrenaline. It functions as a neurohormone, neuromodulator, and neurotransmitter in invertebrates, stimulating alpha2-adrenoceptors and increasing various metabolic processes. It mediates behaviors like learning and memory, regulates endocrine gland activity, and mobilizes lipids and carbohydrates through specific G protein-coupled receptors.
- Acts as a neurohormone, neuromodulator, and neurotransmitter
- Stimulates alpha2-adrenoceptors (ARs)
- Increases glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure
- Regulates sensory input desensitization, arousal, and rhythmic behaviors
- Involved in complex behaviors like learning and memory
- Regulates endocrine gland activity
- Induces lipid and carbohydrate mobilization
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Medchemexpress LLC Ivabradine hydrochloride | 148849-67-6 | 99.7% | 1 ML
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Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker. It inhibits the cardiac pacemaker current (If), reducing heart rate dose-dependently without modifying blood pressure. This compound demonstrates anticonvulsant, anti-ischaemic, and anti-anginal activities.
- Potent and orally active HCN channel blocker
- Inhibits cardiac pacemaker current (If)
- Reduces heart rate dose-dependently
- Exhibits anticonvulsant activity
- Shows anti-ischaemic and anti-anginal effects
- Investigated in clinical trials for conditions such as heart failure and atrial fibrillation
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