Unsubstituted Phenols
Medchemexpress LLC Combretastatin A-1 | 109971-63-3 | >98.0% | 50 MG
Combretastatin A-1 is a cis-stilbene microtubule polymerization inhibitor (CAS 109971-63-3) used in research to study tubulin dynamics and as an experimental antitumor agent. It is supplied as a crystalline solid for research use and is typically handled and stored under cold conditions to preserve stability.
- Microtubule polymerization inhibitor that binds the colchicine site on tubulin.
- Used for cellular assays and in vivo cancer research models.
- Crystalline solid; typically stored at -20°C for long-term stability.
- Molecular weight 332.4 g/mol, chemical formula C18H20O6.
- Provided in research-scale quantities suitable for assay development and preclinical studies.
Medchemexpress LLC ML-109 | 1186649-91-1 | 99.0% | 523.58 | 50 MG
ML-109 is identified as a potent and full agonist of the thyroid stimulating hormone receptor (TSHR), exhibiting an EC50 of 40 nM. While being surprisingly stable under neutral and basic conditions with a half-life of approximately 16 hours, it degrades at lower pH levels, with a half-life of about 3 hours. It shows no activity at FSHR or LHCGR.
- Potent and full thyroid stimulating hormone receptor (TSHR) agonist
- EC50 of 40 nM for TSHR
- No activity at FSHR or LHCGR
- Stable at neutral and basic conditions (t1/2 of ~16 h)
Medchemexpress LLC HY-15237 1mg Medchemexpress, SL 0101-1 CAS:77307-50-7 Purity:>98%
Medchemexpress, HY-15237 1mg SL 0101-1 CAS:77307-50-7 SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC 50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G 1 phase [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC SN-011 (STING Inhibitor) | 2249435-90-1 | 99.9% | C25H19FN2O4S | 50 MG
SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. This compound functions by competing with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, thereby blocking CDN binding and subsequent STING activation. It is intended for research pertaining to STING-driven autoimmune and inflammatory diseases.
- Potent and selective mouse and human STING inhibitor
- IC50 of 76 nM for STING signaling
- Blocks cyclic dinucleotide (CDN) binding and STING activation
- Useful for research of STING-driven autoimmune and inflammatory diseases
- Inhibits 2′3′-cGAMP-induced Ifnb expression in multiple cell types
- Suppresses STING oligomerization, phosphorylation, and ER-to-Golgi translocation
- Inhibits inflammation and autoimmunity in Trex1-/- mice, improving survival
Medchemexpress LLC HY-N0898 10mg Medchemexpress, Catechin CAS:154-23-4 Purity:>98%
Medchemexpress, HY-N0898 10mg Catechin CAS:154-23-4 Catechin inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 1.4 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC IKK-16 S2882-50mg
IKK-16 is a selective I B kinase (IKK) inhibitor for IKK-2 IKK complex and IKK-1 with IC50 of 40 nM 70 nM and 200 nM in cell-free assays respectively IKK-16 also inhibits LRRK2 Ser935 phosphorylation in cells and LRRK2 kinase activity in vitro with IC50 of 50 nM
Medchemexpress LLC HY-N0001 100mg , (-)-Epicatechin (-)-Epicatechol;Epicatechin;epi-Catechin CAS:490-46-0 Purity:98%
Medchemexpress, HY-N0001 100mg (-)-Epicatechin (-)-Epicatechol;Epicatechin;epi-Catechin CAS:490-46-0 Formula:C15H14O6 IC50: 3.2 μM (COX-1) Purity:98% (-)-Epicatechin inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0767 1mg Medchemexpress, Isoorientin CAS:4261-42-1 Purity:>98%
Medchemexpress, HY-N0767 1mg Isoorientin CAS:4261-42-1 Isoorientin is a potent inhibitor of COX-2 with an IC 50 value of 39 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13715 500mg Medchemexpress, Norepinephrine CAS:51-41-2 Purity:>98%
Medchemexpress, HY-13715 500mg Norepinephrine CAS:51-41-2 Norepinephrine (Levarterenol) is a β 1 -selective adrenergic receptor agonist with EC 50 of 5.37 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111832 5mg Medchemexpress, 1,2,3,6-Tetragalloylglucose CAS:79886-50-3 Purity:>98%
Medchemexpress, HY-111832 5mg 1,2,3,6-Tetragalloylglucose CAS:79886-50-3 1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-100563 100mg Medchemexpress, Cyclo(RGDyK) trifluoroacetate CAS:250612-42-1 Purity:>98%
Medchemexpress, HY-100563 100mg Cyclo(RGDyK) trifluoroacetate CAS:250612-42-1 Cyclo(RGDyK) trifluoroacetate is a potent and selective α V β 3 integrin inhibitor with an IC 50 of 20 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N1504 5mg Medchemexpress, Loureirin B CAS:119425-90-0 Purity:>98%
Medchemexpress, HY-N1504 5mg Loureirin B CAS:119425-90-0 Loureirin B, a flavonoid extracted from Dracaena cochinchinensis , is an inhibitor of plasminogen activator inhibitor-1 (PAI-1) , with an IC 50 of 26.10 μM; Loureirin B also inhibits K ATP , the phosphorylation of ERK and JNK , and has anti-diabetic activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-124817 5mg Medchemexpress, Col003 CAS:328565-16-8 Purity:>98%
Medchemexpress, HY-124817 5mg Col003 CAS:328565-16-8 Col003 is a potent inhibitor of Hsp47 , competitively binds to the collagen binding site on Hsp47 ( IC 50 , 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-16561 500mg , Resveratrol trans-Resveratrol CAS:501-36-0 Purity:98%
Medchemexpress, HY-16561 500mg Resveratrol trans-Resveratrol CAS:501-36-0 Formula:C14H12O3 IC50: 0.8 μM (Adenylyl cyclase), 1 μM (IKKβ), 3.3 and 5 μM (DNA polymerase α and δ) Purity:98% Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC 50 of 0.8, 1, 3.3 and 5 μM for adenylyl cyclase, IKKβ , DNA polymerase α and δ, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N1454 5mg Medchemexpress, Apigenin-7-glucuronide CAS:29741-09-1 Purity:>98%
Medchemexpress, HY-N1454 5mg Apigenin-7-glucuronide CAS:29741-09-1 Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC 50 s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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