Benzoxazines
TARGETMOL CHEMICALS INC CHM-1 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CHM-1 is an inducer of apoptosis and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo. purity: 100%
TARGETMOL CHEMICALS INC ATC 0175 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R MCH2R MCH1 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM >10000 nM 13 nM 9.66 nM and 16.9 nM respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders. purity: 99%
TARGETMOL CHEMICALS INC KENPAULLONE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KenPaullone (9-Bromopaullone) a potent CDK1 CDK2 and CDK5 inhibitor as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGF(beta)-Smad3 signaling pathway. purity: 98%
TARGETMOL CHEMICALS INC ESI-09 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 uM respectively. purity: 99%
TARGETMOL CHEMICALS INC WWL123 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM). WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice. purity: 99%
TARGETMOL CHEMICALS INC VIALININ A 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Vialinin A (Terrestrin A) (Terrestrin A) is a p-terphenyl compound with antioxidant properties [1]. Vialinin A is a potent inhibitor of TNF-(alpha) USP4 USP5 and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A (Terrestrin A) is able to be used for autoimmune diseases and cancer research [2] [3]. purity: 99%
TARGETMOL CHEMICALS INC APRICITABINE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 uM) the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase (alpha) (beta) and (gamma) with Ki values of 300 uM 12 uM and 112.25 uM respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients with good tolerability and low selective resistance. purity: 100%
TARGETMOL CHEMICALS INC RO5263397 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. RO5263397 is a TAAR1 specific agonist with oral activity that has been used in antidepressant studies. It has also been found to act as an inhibitor of the enzyme cyclooxygenase-2 (COX-2) which is involved in the synthesis of prostaglandins. purity: 99%
TARGETMOL CHEMICALS INC TH34 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TH34 is an HDAC6/8/10 inhibitor (IC50s 4.6/1.9/7.7 uM). It shows high selectivity over HDAC1/2/3. purity: 98%
TARGETMOL CHEMICALS INC SARDOMOZIDE DIHYDROCHLOR 5MG
Also available in 1mg 10mg 25mg 50mg 100mg and bulk. Please contact Fisher for quotes. Sardomozide dihydrochloride (CGP 48664 dihydrochloride) is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC IC50 = 5 nM). purity: 99%
EMOLECULES INC 238428-26-7 | 3-(Methylsulfonylamino)benzylamine hydrochloride | Combi-Blocks | MFCD09054706 | 236.710 | C8H13ClN2O2S | 97.000 | Cl.CS(=O)(=O)Nc1cccc(CN)c1 | 1g | 232336243
3-(Methylsulfonylamino)benzylamine hydrochloride | Combi-Blocks | 238428-26-7 | MFCD09054706 | 236.710 | C8H13ClN2O2S | 97.000 | Cl.CS(=O)(=O)Nc1cccc(CN)c1 | 1g | 232336243
TARGETMOL CHEMICALS INC OGLEMILAST 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Oglemilast (GRC 3886) suppresses pulmonary cell infiltration including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases. purity: 98%
TARGETMOL CHEMICALS INC LINTITRIPT 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1. purity: 98%
TARGETMOL CHEMICALS INC TUNICAMYCIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bacteria yeasts fungi and viruses and has anti-cancer activity. purity: 98%
TARGETMOL CHEMICALS INC SHMT-IN-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SHMT-IN-1 is a potent plasmodial serine hydroxymethyltransferase (SHMT) inhibitor with antitumor activity. purity: 99%