Piperidines
Medchemexpress LLC Rhodamine-N3 chloride | 2363751-90-8 | 99.9% | 847.44 g·mol⁻¹ | C44H59ClN8O7 | 10 MG
Rhodamine-N3 chloride is an azide-functionalized rhodamine fluorescent dye used to label alkyne-containing biomolecules via click chemistry. It delivers strong fluorescence (excitation 544 nm, emission 576 nm) and is supplied as a solid chloride salt for research applications.
- Azide-functional rhodamine dye for click chemistry labeling.
- Excitation 544 nm, emission 576 nm for reliable fluorescence detection.
- High purity (≈99.85%) and molecular weight 847.44 g·mol⁻¹.
- Solid, brown to black appearance; compatible with common organic solvents.
- Store at 4 °C, sealed, protected from moisture and light.
- Supplied as a 10 mg vial for small-scale labeling experiments.
Medchemexpress LLC Apixaban-13C,d3 (BMS-562247-01-13C,d3) | 1261393-15-0 | 99.5% | C2413CH22D3N5O4 | 1 MG
Apixaban-13C,d3 is a deuterium and 13C labeled version of Apixaban, also known as BMS-562247-01-13C,d3. Apixaban is recognized as a highly selective and reversible inhibitor of Factor Xa, demonstrating Ki values of 0.08 nM in humans and 0.17 nM in rabbits.
- Deuterium and 13C labeled compound.
- Highly selective, reversible inhibitor of Factor Xa.
- Can be used as a tracer in drug development processes.
- Suitable as an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
Medchemexpress LLC 1-(Chlorocarbonyl)piperidine-d10 | 1219803-31-2 | 98.2% | 157.66 | 1 MG
1-(Chlorocarbonyl)piperidine-d10 is the deuterium labeled 1-(Chlorocarbonyl)piperidine. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Piperidine-4-carboxamide-d9 | 1219803-20-9 | 98.2% | 137.23 | 5 MG
Piperidine-4-carboxamide-d9 is the deuterium labeled Piperidine-4-carboxamide. It is for research use only. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Loperamide-d6 hydrochloride | 1189469-46-2 | 99.07% | 1 MG
Loperamide-d6 (hydrochloride) is a deuterium-labeled Loperamide hydrochloride. Loperamide hydrochloride itself is an opioid receptor agonist used for the treatment of diarrhea. This compound is intended for research use only and is not sold to patients.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Rhodamine-N3 chloride | 2363751-90-8 | 99.9% | 847.44 | 5 MG
Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye utilized for labeling biomolecules that contain alkyne groups. It functions as a click chemistry reagent, possessing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups, exhibiting an excitation/emission (Ex/Em) profile of 544/576 nm.
- Azide-rhodamine fluorescent dye
- Click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
- Excitation/emission (Ex/Em) = 544/576 nm
- Enables labeling of biomolecules with alkyne groups
- Versatile for various click chemistry applications
Medchemexpress LLC Piperidine-4-carboxamide-d9 | 1219803-20-9 | 98.2% | 137.23 | 1 MG
Piperidine-4-carboxamide-d9 is the deuterium labeled Piperidine-4-carboxamide. It is for research use only and not sold to patients. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Donepezil-d4 hydrochloride | 1219798-88-5 | 100.0% | C24H26D4ClNO3 | 5 MG
Donepezil-d4 hydrochloride is a deuterium-labeled form of Donepezil hydrochloride. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. It demonstrates high selectivity for AChE over BuChE and exhibits a neuroprotective effect on Aβ42 neurotoxicity.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Nelfinavir | 159989-64-7 | C32H45N3O4S | 25 MG
Nelfinavir is a potent and orally bioavailable inhibitor of HIV-1 protease, exhibiting a Ki of 2 nM, and is utilized for HIV infection. It also acts as a broad-spectrum anticancer agent.
- Potent and orally bioavailable protease inhibitor.
- Inhibits protease with a Ki of 2 nM.
- Broad-spectrum anticancer activity.
- Treatment of HIV infection.
- Anticancer research.
- Use as an analytical standard.
- Isotope-labeled for specific research.
Medchemexpress LLC Piperidine-4-carboxamide-d9 | 1219803-20-9 | 98.2% | 137.23 | 10 MG
Piperidine-4-carboxamide-d9 is the deuterium labeled Piperidine-4-carboxamide. It is a stable heavy isotope of hydrogen, carbon, and other elements incorporated into drug molecules, primarily as a tracer for quantitation during drug development. Deuteration has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for quantitative analysis
- Functions as an internal standard for quantitative analysis
- Applicable for NMR, GC-MS, or LC-MS analysis
- Affects pharmacokinetic and metabolic profiles of drugs
Apexbio Technology LLC Hoechst 33342/PI Double Staining Kit 500T
Hoechst 33342 PI Double Staining Kit is a fluorescence-based assay kit designed to distinguish apoptosis and necrosis in cell populations The kit utilizes two fluorescent probes Hoechst 33342 and propidium iodide (PI) to assess plasma membrane integrity and nuclear morphology Hoechst 33342 penetrates live cells and binds to DNA producing blue fluorescence with intensity increasing upon apoptotic chromatin condensation PI is impermeable to intact cell membranes and selectively labels necrotic cells with red fluorescence Compared to single-stain apoptosis assays this dual-stain approach enables simultaneous detection of viable apoptotic and necrotic cells Based on these properties Hoechst 33342 PI Double Staining Kit is applicable in pharmacological evaluation and cytotoxicity studies
Apexbio Technology LLC Hoechst 33342/PI Double Staining Kit 100T
Hoechst 33342 PI Double Staining Kit is a fluorescence-based assay kit designed to distinguish apoptosis and necrosis in cell populations The kit utilizes two fluorescent probes Hoechst 33342 and propidium iodide (PI) to assess plasma membrane integrity and nuclear morphology Hoechst 33342 penetrates live cells and binds to DNA producing blue fluorescence with intensity increasing upon apoptotic chromatin condensation PI is impermeable to intact cell membranes and selectively labels necrotic cells with red fluorescence Compared to single-stain apoptosis assays this dual-stain approach enables simultaneous detection of viable apoptotic and necrotic cells Based on these properties Hoechst 33342 PI Double Staining Kit is applicable in pharmacological evaluation and cytotoxicity studies
Medchemexpress LLC Donepezil-d4 hydrochloride (E2020-d4) | 1219798-88-5 | 99.96% | C24H26D4ClNO3 | 1 MG
Donepezil-d4 (hydrochloride) is the deuterium labeled Donepezil hydrochloride. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE and exhibits neuroprotective effect on Aβ42 neurotoxicity.
- Acts as a reversible, selective AChE inhibitor.
- Demonstrates high selectivity for AChE over BuChE.
- Shows neuroprotective effects against Aβ42 neurotoxicity.
- Can be utilized as a tracer in research.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes can influence pharmacokinetic and metabolic profiles of drugs.
Apexbio Technology LLC Autophagy/Cytotoxicity Dual Staining Kit (MDC/PI) 500tests
Autophagy Cytotoxicity Dual Staining Kit MDC PI is a dual-fluorescent dye kit designed to assess autophagic activity and cytotoxicity in live cells It employs monodansylcadaverine (MDC) which labels autophagic vacuoles by associating with acidic lipid-containing compartments and propidium iodide (PI) which stains cells with compromised membranes indicative of severe injury or cell death Autophagy Cytotoxicity Dual Staining Kit MDC PI enables simultaneous detection of autophagy and cytotoxicity by fluorescent staining In cell-based studies it allows real-time visualization and analysis of autophagic activity and cell membrane integrity Based on these properties Autophagy Cytotoxicity Dual Staining Kit MDC PI is suitable for research applications in autophagy cytotoxicity pharmacological assessment and mechanistic studies related to disease models
Apexbio Technology LLC Autophagy/Cytotoxicity Dual Staining Kit (MDC/PI) 2000tests
Autophagy Cytotoxicity Dual Staining Kit MDC PI is a dual-fluorescent dye kit designed to assess autophagic activity and cytotoxicity in live cells It employs monodansylcadaverine (MDC) which labels autophagic vacuoles by associating with acidic lipid-containing compartments and propidium iodide (PI) which stains cells with compromised membranes indicative of severe injury or cell death Autophagy Cytotoxicity Dual Staining Kit MDC PI enables simultaneous detection of autophagy and cytotoxicity by fluorescent staining In cell-based studies it allows real-time visualization and analysis of autophagic activity and cell membrane integrity Based on these properties Autophagy Cytotoxicity Dual Staining Kit MDC PI is suitable for research applications in autophagy cytotoxicity pharmacological assessment and mechanistic studies related to disease models
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