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Filtered Search Results
![eMolecules 842133-18-0 | Canagliflozin | Ambeed | MFCD18251436 | 444.520 | C24H25FO5S | 95.000 | Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 250mg | 525189895](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000128653.jpg-250.jpg)
eMolecules 842133-18-0 | Canagliflozin | Ambeed | MFCD18251436 | 444.520 | C24H25FO5S | 95.000 | Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 250mg | 525189895
Canagliflozin | Ambeed | 842133-18-0 | MFCD18251436 | 444.520 | C24H25FO5S | 95.000 | Cc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | 250mg | 525189895
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Medchemexpress LLC Glycinexylidide | 18865-38-8 | MFCD05267700 | 95.1% | 178.23 g/mol | C10H14N2O | 250 MG
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Glycinexylidide is the active metabolite of lidocaine supplied as a research reagent for biochemical, pharmacokinetic, and in vitro pharmacology studies. It is used as a reference standard and for investigations into lidocaine metabolism and sodium channel-related activity.
- Active metabolite of lidocaine used in metabolism and pharmacokinetic studies.
- Supplied as a research-grade chemical reagent for laboratory use.
- Available in small analytical quantities suitable for assay and reference standard use.
- Purity around 95.1%, supporting reproducible experimental results.
- Molecular formula C10H14N2O and molecular weight 178.23 g/mol.
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Medchemexpress LLC Anti-B7-H4 VTCN1 Ant 1mg | 1mg
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Anti-B7-H4/VTCN1 Antibody is a CHO-expressed human antibody that targets B7-H4/VTCN1 The Anti-B7-H4/VTCN1 Antibody contains a huIgG1 heavy chain and a hu light chain with a predicted molecular weight (MW) of 145 kDa The isotype control for Anti-B7-H4/VTCN1 Antibody can be referenced as Human IgG1 kappa Isotype Control (HY-P99001)
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Medchemexpress LLC Chloroacetamido-C4-N 250mg
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Chloroacetamido-C4-NHBoc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Copanlisib dihydrochloride | 1402152-13-9 | C23H30Cl2N8O4 | 50 MG
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Copanlisib dihydrochloride is a potent, selective, and ATP-competitive pan-class I PI3K inhibitor. It exhibits IC50 values of 0.5 nM for PI3Kα, 0.7 nM for PI3Kδ, 3.7 nM for PI3Kβ, and 6.4 nM for PI3Kγ. This compound demonstrates superior antitumor activity and shows over 2,000-fold selectivity against other lipid and protein kinases, with the exception of mTOR.
- Induces apoptosis in a subset of tumor cell lines resistant to certain treatments.
- Shows complete inhibition of PI3K-mediated AKT phosphorylation in ELT3 cells at 5 nM.
- Potently inhibits cell proliferation in various human tumor cell lines, particularly those with PIK3CA-activating mutations or HER2-positive.
- Significantly increases caspase-9 activities and levels of phosphorylated p53 at Ser15 and cleaved PARP in BT20 breast cancer cells.
- Demonstrates robust antitumor activity in rat KPL4 tumor xenograft models, with high tumor growth inhibition rates.
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Medchemexpress LLC HY-101267 100mg Medchemexpress, CHMFL-BMX-078 CAS:1808288-51-8 Purity:>98%
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Medchemexpress, HY-101267 100mg CHMFL-BMX-078 CAS:1808288-51-8 CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC 50 of 11 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-18252 100mg Medchemexpress, Avanafil TA1790 CAS:330784-47-9 Purity:98%
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Medchemexpress,HY-18252 100mg Avanafil TA1790 CAS:330784-47-9 Formula:C23H26ClN7O3 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377980 CERDULATINIB HYDROC 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378589 CERDULATINIB HYDROC 50MG
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Medchemexpress LLC Gusacitinib | 1425381-60-7 | MFCD31692335 | 99.4% | 460.5 g/mol | C24H28N8O2 | 100 MG
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Gusacitinib is an orally active dual spleen tyrosine kinase (SYK) and Janus kinase (JAK) inhibitor supplied for research use in biochemical, cellular, and preclinical studies. The material is characterized by analytical data and supplied with documentation to support research applications.
- Dual SYK/JAK inhibitory activity for immune signaling research.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid for formulation and dosing flexibility.
- Documented characterization with COA and analytical data.
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Medchemexpress LLC Protac BET degrader-10 | 1957234-97-7 | 99.4% | 783.29 g/mol | C39H39ClN8O6S | 5 MG
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PROTAC BET Degrader-10 is a small-molecule proteolysis-targeting chimera designed to induce degradation of BET family proteins, primarily BRD4. Reported in patent WO2017007612A1 (example 37), the compound links cereblon and BRD4 ligands and has a reported DC50 of 49 nM. Typical analytical data include CAS 1957234-97-7, molecular formula C39H39ClN8O6S, molecular weight 783.29 g/mol, and purity ~99.39%.
- Induces selective BRD4 degradation in cellular assays.
- Reported DC50 of approximately 49 nM for BRD4 degradation.
- Available as solid and as a 10 mM solution in DMSO for assay flexibility.
- High chemical purity suitable for biochemical and cellular studies.
- Applicable to PROTAC mechanism-of-action and epigenetic research.
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Medchemexpress LLC PROTAC BET Degrader-10 | 1957234-97-7 | 99.4% | 783.29 | 50 MG
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PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader. It is connected by ligands for Cereblon and BRD4, and has a DC50 of 49 nM. This product is for research use only and not sold to patients. PROTACs use two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent BET protein BRD4 degrader
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- Connected by ligands for Cereblon and BRD4
- DC50 of 49 nM
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Medchemexpress LLC HY-103633 10mg Medchemexpress, PROTAC BET Degrader-1 CAS:2093386-22-0 Purity:>98%
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Medchemexpress, HY-103633 10mg PROTAC BET Degrader-1 CAS:2093386-22-0 PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10993 100mg , MK-1775 AZD1775;Adavosertib CAS:955365-80-7 Purity:98%
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Medchemexpress, HY-10993 100mg MK-1775 AZD1775;Adavosertib CAS:955365-80-7 Formula:C27H32N8O2 IC50: 5.2 nM (Wee1) Purity:98% MK-1775 is a potent Wee1 inhibitor with IC 50 of 5.2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2093388-33-9 | Medchem Express | PROTAC BET degrader-2 | 5mg | 441681950 | HY-114228 | 770.851 | C41H42N10O6
Ambeed | 4-(2-Chloro-9H-purin-6-yl)morpholine | 250mg | 627733801 | A679575 | 4010-81-5 | MFCD17430374 | 239.660 | C9H10ClN5O
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