Quinolines and derivatives
2,2'-Bicinchoninic Acid Dipotassium Salt Hydrate 98.0+%, TCI America™
CAS: 63451-34-3 Molecular Formula: C20H12K2N2O4 Molecular Weight (g/mol): 422.523 MDL Number: MFCD00014664 InChI Key: HRNSKWTYGVQLDN-UHFFFAOYSA-N PubChem CID: 66596657 IUPAC Name: 2-(4-carboxyquinolin-2-yl)quinoline-4-carboxylic acid;potassium SMILES: C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)O)C(=O)O.[K].[K]
Medchemexpress LLC 8-Hydroxyquinoline (8-Quinolinol) | 148-24-3 | >99.9% | 5 G
8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that functions as a fungicide. It exhibits a MIC range of 27.56-55.11 μM (4-8 μg/mL) against clinical isolates of *Neisseria gonorrhoeae*. This compound can bind to copper, forming complexes that facilitate copper transport into cells. Additionally, 8-Hydroxyquinoline leads to an increase in micronucleated polychromatic erythrocytes and can cause hair depigmentation in mice.
- Functions as a fungicide
- Exhibits a MIC range of 27.56-55.11 μM (4-8 μg/mL) against clinical isolates of Neisseria gonorrhoeae
- Binds to copper, forming complexes that facilitate copper transport into cells
- Can lead to an increase in micronucleated polychromatic erythrocytes
- May cause hair depigmentation in mice
Medchemexpress LLC 8-Hydroxyquinoline | 148-24-3 | 99.95% | 1 G
8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator used as a fungicide. It demonstrates an MIC range of 27.56-55.11 μM (4-8 μg/mL) against clinical isolates of *Neisseria gonorrhoeae*. The compound binds to copper, forming complexes that facilitate copper transport into cells. It has also been observed to increase micronucleated polychromatic erythrocytes and cause hair depigmentation in mice. This product is for research use only and is not sold to patients.
- Functions as a lipophilic metal chelator and fungicide
- Exhibits activity against *Neisseria gonorrhoeae*
- Binds to copper to facilitate cellular transport
- Increases micronucleated polychromatic erythrocytes in mice
- May cause hair depigmentation in mice
- Induces cytotoxicity in various cell lines
- Inhibits proteasomal chymotrypsin-like activity
- Reduces inflammation by inhibiting NO production and iNOS expression
Medchemexpress LLC Dibenzocyclooctyne-amine | 1255942-06-3 | MFCD22380759 | 99.1% | 276.34 | C18H16N2O | 1 G
DBCO-amine is a dibenzocyclooctyne-functionalized amine reagent used for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition, SPAAC). It is supplied at high purity for bioconjugation and linker synthesis, and is suitable for labeling azide-bearing biomolecules.
- Enables copper-free SPAAC bioconjugation with azide groups
- High purity suitable for synthetic and bioconjugation workflows
- Available in multiple pack sizes, including 1 g for scale-up
- Used for ADC linker synthesis and labeling applications
- Soluble in common organic solvents such as DMSO
Medchemexpress LLC 8-Hydroxyquinoline | 10 MM 1 ML
8-Hydroxyquinoline (8-Quinolinol) is a versatile compound acting as a lipophilic metal chelator and a fungicide. It demonstrates activity against *Neisseria gonorrhoeae* and can interact with copper to facilitate cellular transport. Research indicates its potential to increase micronucleated polychromatic erythrocytes and cause hair depigmentation in mice.
- Acts as a lipophilic metal chelator
- Functions as a fungicide
- Effective against *Neisseria gonorrhoeae*
- Binds to copper and facilitates transport into cells
- Increases micronucleated polychromatic erythrocytes
- Can cause hair depigmentation in mice
Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 1 ML
3,7,4'-Trihydroxyflavone, also known as 5-Deoxykampferol, is a flavonoid compound isolated from the stems of Rhus javanica var. roxburghiana. It exhibits anti-inflammatory and antioxidant properties by scavenging various reactive oxygen species (ROS) and reactive nitrogen species (RNS), and can also cleave DNA in the presence of copper ions.
- Isolated from natural sources like Rhus javanica var. roxburghiana.
- Functions as an anti-inflammatory agent.
- Possesses antioxidant activities.
- Capable of scavenging reactive oxygen and nitrogen species.
- Can cleave DNA when copper ions are present.
Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | MFCD03453246 | ≥97.0% | C22H46N4O10 | 5 G
Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Utilized in the synthesis of PROTACs
Medchemexpress LLC Etonogestrel | 54048-10-1 | 99.9% | 200 MG
Etonogestrel is an active metabolite of Desogestrel, functioning as a third-generation progesterone analogue used in various oral contraceptive preparations. It also serves as a click chemistry reagent, featuring an Alkyne group that enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Etonogestrel is known to decrease PHOX2B expression by binding to the progesterone nuclear receptor PR-B.
- Third-generation progesterone analogue
- Included in oral contraceptive preparations
- Click chemistry reagent with an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Decreases PHOX2B expression by binding to the progesterone nuclear receptor PR-B
Medchemexpress LLC Azido-PEG8-amine | 857891-82-8 | 99.9% | C18H38N4O8 | 50MG
Azido-PEG8-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne group molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid | 846549-37-9 | 98.6% | C22H42N4O12 | 250 MG
This PEG-based PROTAC linker, 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid, is designed for the synthesis of PROTACs. It functions as a click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. It is intended for research use only.
- Utilizes PEG-based PROTAC linker technology
- Features an azide group for click chemistry reactions
- Supports copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Suitable for PROTAC synthesis
Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | 97.0% | C22H46N4O10 | 50 MG
Azido-PEG10-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, which can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Ethanamine, 2-(2-azidoethoxy)- | 464190-91-8 | ≥98.0% | C4H10N4O | 250 MG
Azido-PEG1-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Reacts via copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts via strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Azido-PEG23-amine | 2172677-19-7 | 1023457 | 99.9% | C48H98N4O23 | 25 MG
Azido-PEG23-amine is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with alkyne-containing molecules
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with DBCO or BCN group-containing molecules
Medchemexpress LLC Azido-PEG5-amine | 516493-93-9 | 98.0% | C12H26N4O5 | 250 MG
Azido-PEG5-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC L-azidonorleucine (hydrochloride) | 1454334-76-9 | 98.0% | 200 MG
L-Azidonorleucine hydrochloride is an unnatural amino acid that serves as a methionine surrogate. It is used to label mammalian cell proteins and identify various methionyl-tRNA synthetase (MetRS) mutants. This compound functions as a click chemistry reagent due to its azide group, which enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Unnatural amino acid and methionine surrogate
- Labels mammalian cell proteins
- Identifies methionyl-tRNA synthetase (MetRS) mutants
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions