Quinolines and derivatives
2,2'-Bicinchoninic Acid Dipotassium Salt Hydrate 98.0+%, TCI America™
CAS: 63451-34-3 Molecular Formula: C20H12K2N2O4 Molecular Weight (g/mol): 422.523 MDL Number: MFCD00014664 InChI Key: HRNSKWTYGVQLDN-UHFFFAOYSA-N PubChem CID: 66596657 IUPAC Name: 2-(4-carboxyquinolin-2-yl)quinoline-4-carboxylic acid;potassium SMILES: C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)O)C(=O)O.[K].[K]
Medchemexpress LLC Dibenzocyclooctyne-amine | 1255942-06-3 | MFCD22380759 | 99.1% | 276.34 | C18H16N2O | 1 G
DBCO-amine is a dibenzocyclooctyne-functionalized amine reagent used for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition, SPAAC). It is supplied at high purity for bioconjugation and linker synthesis, and is suitable for labeling azide-bearing biomolecules.
- Enables copper-free SPAAC bioconjugation with azide groups
- High purity suitable for synthetic and bioconjugation workflows
- Available in multiple pack sizes, including 1 g for scale-up
- Used for ADC linker synthesis and labeling applications
- Soluble in common organic solvents such as DMSO
Medchemexpress LLC Azido-PEG7-amine | 1333154-77-0 | MFCD13185016 | >98.0% | 394.46 g/mol | C16H34N4O7 | 50 MG
Azido-PEG7-amine is a bifunctional polyethylene glycol (PEG) linker bearing an azide and a primary amine terminus. It is used as a click-chemistry building block and as a linker in antibody-drug conjugate (ADC) and PROTAC synthesis.
- Bifunctional azide and primary amine termini suitable for conjugation.
- PEG7 spacer provides a short, flexible linker (seven ethylene glycol units).
- Compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted click reactions.
- High reported purity, typically greater than 98%.
- Supplied in small laboratory pack sizes for research use.
Medchemexpress LLC Azido-PEG12-amine | 2803478-25-1 | 98.0% | 614.73 g/mol | C26H54N4O12 | 50 MG
Azido-PEG12-amine is a PEG12 linker with an azide group at one terminus and a primary amine at the other, designed for bioconjugation and click chemistry applications.
- Azide functionality enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Primary amine enables conjugation to activated carboxylates such as NHS esters.
- Molecular weight approximately 614.73 g/mol; formula C26H54N4O12.
- High purity by NMR (typically 98.0%).
- Water-soluble PEG12 linker suitable for linker synthesis, PROTACs, and ADCs.
- Store sealed at 4°C, protect from moisture and light.
Medchemexpress LLC Sulfo-Cy7.5 DBCO | 99.8% | 1315.68 | C61H57K3N4O14S4 | 10 MG
Sulfo-Cy7.5 DBCO is a sulfonated near-infrared fluorescent dye bearing a DBCO reactive group. The sulfonate groups increase water solubility, enabling aqueous labeling of biomolecules for imaging and tracking applications.
- Water-soluble sulfonated cyanine dye suitable for aqueous labeling.
- Near-infrared fluorescence for deep-tissue and low-background imaging.
- DBCO reactive group enables copper-free click conjugation to azide-tagged biomolecules.
- High purity suitable for sensitive protein and antibody labeling workflows.
- Store dry at -20°C and protect from light and moisture.
Apexbio Technology LLC Cy5.5 alkyne (non-sulfonated) 25mg
Cy5 5 alkyne non-sulfonated is a near-infrared fluorescent cyanine derivative equipped with an alkyne functional group for click chemistry applications Through copper-catalyzed azide-alkyne cycloaddition (CuAAC) it forms covalent conjugates with azide-containing biomolecules metabolites or small-molecule ligands Cy5 5 alkyne non-sulfonated is primarily soluble in organic solvents aqueous solutions containing organic co-solvent such as DMSO may be used during conjugation Based on these chemical properties Cy5 5 alkyne non-sulfonated holds research potential in labeling nucleic acids peptides proteins lipids and other biomolecules for biomedical imaging tissue distribution evaluation and related pharmaceutical research applications
Apexbio Technology LLC Cy5.5 alkyne (non-sulfonated) 50mg
Cy5 5 alkyne non-sulfonated is a near-infrared fluorescent cyanine derivative equipped with an alkyne functional group for click chemistry applications Through copper-catalyzed azide-alkyne cycloaddition (CuAAC) it forms covalent conjugates with azide-containing biomolecules metabolites or small-molecule ligands Cy5 5 alkyne non-sulfonated is primarily soluble in organic solvents aqueous solutions containing organic co-solvent such as DMSO may be used during conjugation Based on these chemical properties Cy5 5 alkyne non-sulfonated holds research potential in labeling nucleic acids peptides proteins lipids and other biomolecules for biomedical imaging tissue distribution evaluation and related pharmaceutical research applications
Medchemexpress LLC Azido-PEG2-C2-amine | 166388-57-4 | MFCD13189985 | >97.0% | 174.20 g·mol⁻¹ | C6H14N4O2 | 100 MG
Azido-PEG2-C2-amine is a PEG-based bifunctional linker bearing an azide and a primary amine. It is used as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and as a linker in PROTAC and antibody-drug conjugate (ADC) synthesis.
- Azide functional group for click chemistry (CuAAC and SPAAC).
- Primary amine for conjugation to carboxyl and activated ester groups.
- PEG2 spacer provides water solubility and flexible linker length.
- Typically supplied as a solid suitable for standard conjugation workflows.
- Reported purity >97.0% and molecular weight 174.20 g·mol⁻¹.
Medchemexpress LLC Pacma 31 | 1401089-31-3 | 99.3% | 430.47 g·mol⁻1 | C21H22N2O6S | 100 MG
PACMA 31 is an irreversible small-molecule inhibitor of protein disulfide isomerase (PDI) used in biochemical and cellular research. It covalently modifies active-site cysteines, has shown tumor-targeting activity in preclinical studies, and contains an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition for conjugation and probe development.
- Irreversible inhibitor of protein disulfide isomerase for biochemical and cellular assays.
- Forms covalent bond with active-site cysteines for sustained target engagement.
- Contains an alkyne group suitable for click chemistry conjugation.
- High purity suitable for research use.
- Available in multiple pack sizes for flexible experimental needs.
Medchemexpress LLC N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine ethyl ester | 1401089-31-3 | 99.3% | 430.47 | C21H22N2O6S | 50 MG
PACMA 31 is an irreversible small-molecule inhibitor of protein disulfide isomerase (PDI) used for biochemical and cell-based research. It covalently modifies PDI active-site cysteines, has a reported IC50 of about 10 μM, shows tumor-targeting activity in preclinical models, and contains an alkyne group compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
- Irreversible PDI inhibitor that covalently modifies active-site cysteines.
- Reported IC50 of approximately 10 μM for PDI activity inhibition.
- Demonstrated tumor-targeting activity in preclinical studies.
- Contains an alkyne functional group for CuAAC click chemistry applications.
- Solid form and high reported purity suitable for research use.
Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | 98.5% | 482.57 g/mol | C20H42N4O9 | 250 MG
Azido-PEG9-amine is an azide-terminated polyethylene glycol linker containing nine ethylene glycol units and a terminal primary amine, used as a click-chemistry reagent and as a non-cleavable PEG9 linker in bioconjugation applications.
- Azide-terminated PEG linker with nine ethylene glycol units.
- Terminal primary amine for further conjugation.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC).
- Suitable for antibody-drug conjugate (ADC) and proteolysis targeting chimera (PROTAC) synthesis and general bioconjugation.
- CAS number 1207714-69-9; molecular weight 482.57 g/mol; formula C20H42N4O9; purity 98.5%.
- Supplied as 250 mg quantity for laboratory-scale synthesis.
Medchemexpress LLC Sulfo-Cy3 azide | 1801695-56-6 | MFCD30527437 | 99.6% | 806.97 | C35H46N6O10S3 | 10 MG
Sulfo-Cy3 Azide is a water-soluble Cy3 fluorescent dye bearing an azide functional group for bioorthogonal click chemistry. It is designed for labeling sensitive biomolecules, such as proteins, via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC). The dye exhibits excitation/emission around 550/570 nm and is supplied in research pack sizes.
- Water-soluble cyanine dye suitable for aqueous labeling reactions.
- Azide functional group enables CuAAC and SPAAC click chemistry.
- Excitation/emission approximately 550/570 nm for bright fluorescence.
- Soluble in DMSO at 50 mg/mL (requires sonication; use fresh DMSO).
- High purity suitable for research applications.
Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | 98.5% | 482.57 g/mol | C20H42N4O9 | 50 MG
Azido-PEG9-amine is a non-cleavable nine-unit polyethylene glycol (PEG) linker bearing an azide and a terminal amine. It is used for antibody-drug conjugate and PROTAC synthesis and enables bioconjugation via click chemistry (CuAAC and SPAAC).
- Molecular formula: C20H42N4O9.
- Molecular weight: 482.57 g/mol.
- Cas number: 1207714-69-9.
- Purity: 98.52%.
- Available package sizes: 50 mg, 100 mg, 250 mg, 500 mg, 1 g.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition for bioconjugation.
Medchemexpress LLC Sulfo-Cy5.5 azide | 1955527-41-9 | MFCD28334525 | ≥95.0% | 999.16 | C44H50N6O13S4 | 10 MG
Sulfo-Cy5.5 Azide is a water-soluble, far-red fluorescent click-chemistry reagent containing an azide functional group for covalent labeling of peptides, proteins, and oligonucleotides. It is suitable for imaging applications and reacts via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC); excitation is ~673 nm with emission ~707 nm.
- Water-soluble fluorescent dye suitable for aqueous labeling reactions.
- Azide functional group enables CuAAC and SPAAC click chemistries.
- Far-red emission for reduced background and deep-tissue imaging.
- High purity (≥95.0%) for reliable labeling results.
- Soluble in DMSO at 50 mg/mL with gentle warming and sonication.
- Store protected from light; in solvent store at -80°C for long term.
Medchemexpress LLC Sulfo-Cy5 azide | 1782950-80-4 | >90.0% | C37H48N6O10S3 | 10MG
Sulfo-Cy5 azide is a water-soluble, azide-functionalized fluorescent dye intended for bioconjugation via click chemistry. It absorbs at 647 nm and emits at 663 nm, and is supplied as a blue powder with a molecular weight of approximately 833.01 g/mol and reported purity ≥90% (HPLC). The reagent is designed for labeling biomolecules in aqueous conditions and should be stored at -20 °C.
- Water-soluble for efficient labeling in aqueous buffers.
- Provides far-red fluorescence (λabs 647 nm, λem 663 nm) for imaging and detection.
- Azide functionality enables copper-catalyzed and strain-promoted click chemistry conjugation.
- High purity (>90.0%) suitable for sensitive applications.
- Blue powder form for easy aliquoting and storage.
- Stable when stored at -20 °C with a typical shelf life of 12 months.