Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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2,356 – 2,370 of 6,662 results

2,356

Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML

AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML

Pricing & Availability

2,357

Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 | C14H20Cl2N4O2 | 1 ML

Cl-amidine hydrochloride is an orally active peptidylarginine deiminase (PAD) inhibitor used in biochemical, cellular, and in vivo research to block protein citrullination and probe PAD-related pathways.

Inhibits PAD1, PAD3, and PAD4 with reported IC50 values of 0.8 μM, 6.2 μM, and 5.9 μM.
Available as a 10 mM solution in DMSO or as solid quantities for formulation flexibility.
High purity (~99.8%) suitable for biochemical and cellular assays.
Demonstrated activity in cell apoptosis and neutrophil extracellular trap formation assays.
Shows efficacy in murine models of colitis and sepsis in published studies.
Provided supporting documents: data sheet, SDS, COA, HNMR, RP-HPLC, and LCMS.

Pricing & Availability

2,358

Medchemexpress LLC Antalarmin hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 1 ML

Antalarmin hydrochloride is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist used in research to suppress CRH-induced ACTH secretion and to study stress- and inflammation-related responses in animal models.

Selective CRHR1 antagonist with reported Ki ≈ 1 nM.
CAS number 220953-69-5.
Molecular formula C24H35ClN4, MW 415.01 g/mol.
Available as a solid or as a 10 mM solution in DMSO (1 mL).
High purity (~99.9%) suitable for analytical and in vivo preparations.
Recommended storage: solid at -20°C; in solvent store at -80°C for long term.

Pricing & Availability

2,359

Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 50 MG

SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) antagonist, which has demonstrated potent activity with Ki values of 57 nM and 27 nM in whole cell and membrane assays, respectively. It exhibits a high degree of specificity, showing 50-fold selectivity over the OX2 receptor. This compound is intended for research purposes only and is not sold to patients.

Selective non-peptide orexin receptor 1 (OX1) antagonist.
Ki values of 57 nM (whole cell) and 27 nM (membrane).
Exhibits 50-fold selectivity over OX2 receptor.

Pricing & Availability

2,360

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG

Melitracen hydrochloride is a research-grade tricyclic antidepressant hydrochloride salt supplied for laboratory use. It is used in pharmacological studies of monoamine neurotransmitter uptake and serotonergic (5-HT) receptor pathways. Provided as a solid for in vitro and preclinical research; not for human or veterinary use.

Tricyclic antidepressant hydrochloride salt.
Molecular formula C21H26ClN.
Molecular weight 327.89.
Purity >98.0% (HPLC).
Available as a solid powder, commonly in 200 MG quantities.
For research use only; not for human or veterinary use.

Pricing & Availability

2,361

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG

Azasetron hydrochloride is a benzamide derivative functioning as a potent and selective 5-HT3 receptor antagonist. It is utilized in studies concerning chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist
Used in studies for chemotherapy-induced nausea and vomiting (CINV)
Purity of 99.76%
Solid, white to off-white appearance
Effectively penetrates skin in in vivo studies
IC50 for 5-HT3 Receptor is 0.33 nM

Pricing & Availability

2,362

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 50 MG

Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent. It also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function.

Oral glucose-lowering agent
Reduces reactive oxygen species production
Increases mitochondrial DNA
Improves mitochondrial function

Pricing & Availability

2,363

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG

Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to the estrogen receptor, and it also inhibits aromatase activity. It has potential for breast cancer study.

Key active metabolite of Tamoxifen (TAM).
Higher affinity and specificity to estrogen receptor.
Inhibits aromatase activity.
Potential for breast cancer study.
Approximately 100-fold more potent as an antagonist of the ER than tamoxifen.
Targets estrogen receptor α for degradation in breast cancer cells.
Blocks ERA transcriptional activity and inhibits estrogen-induced breast cancer cell proliferation.

Pricing & Availability

2,364

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG

Ansofaxine hydrochloride is a triple reuptake inhibitor designed to inhibit serotonin, dopamine, and norepinephrine reuptake. It demonstrates IC50 values of 723 nM, 491 nM, and 763 nM for these reuptake processes, respectively. This compound is intended for research use only.

Triple reuptake inhibitor
Inhibits serotonin, dopamine, and norepinephrine reuptake
Intended for research use only
Appears as a solid
Color ranges from white to off-white
Recommended storage for solid is 4°C, sealed and away from moisture
For solutions, store at -80°C for up to 6 months, or -20°C for 1 month

Pricing & Availability

2,365

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML

Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.

Acts as a cannabinoid receptor type 1 (CB1) agonist
Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
Suppresses the transcriptional activity of the androgen receptor
Extracted from the bark of pine trees
Appears as a white to off-white solid
Store at -20°C in sealed conditions, away from moisture
For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture

Pricing & Availability

2,366

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 25 MG

Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent that reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function. This compound appears as a white to off-white solid.

Oral glucose-lowering agent
Reduces reactive oxygen species (ROS) production
Increases mitochondrial DNA
Improves mitochondrial function
Soluble in H2O (≥ 50 mg/mL)
Soluble in DMSO (25 mg/mL)

Pricing & Availability

2,367

Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | C18H29ClN2O3S | 5 MG

SB-269970 hydrochloride is a potent, selective, and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. It exhibits >50-fold selectivity against other 5-HT receptors.

Potent and selective 5-HT7 receptor antagonist
Brain-penetrant
Demonstrates greater than 50-fold selectivity against other 5-HT receptors
Significantly blocks amphetamine and ketamine-induced hyperactivity in animal models

Pricing & Availability

2,368

Medchemexpress LLC Ribociclib hydrochloride | 1211443-80-9 | >99.9% | 471.00 | 10 MG

Ribociclib hydrochloride is an ATP-competitive and orally active CDK4/6 inhibitor designed for research use. It effectively crosses the blood-brain barrier and demonstrates potent inhibitory activity against CDK4 and CDK6.

ATP-competitive and orally active CDK4/6 inhibitor
Crosses the blood-brain barrier
IC50 values of 10 nM for CDK4 and 39 nM for CDK6
Over 1,000-fold less potent against the cyclin B/CDK1 complex
Induces cell-cycle arrest in G0/G1 phase
Significantly delays tumor growth in neuroblastoma xenografts

Pricing & Availability

2,369

Medchemexpress LLC Ravidasvir (hydrochloride) | 1303533-81-4 | MFCD32705191 | 99.9% | 835.82 | C42H52Cl2N8O6 | 5MG

Ravidasvir hydrochloride is the hydrochloride salt of ravidasvir, a pan-genotypic hepatitis C virus (HCV) NS5A inhibitor supplied for research use. It is provided as solid vials in multiple sizes and as DMSO solutions for immediate assay use. Intended for in vitro research and assay development; not for human or clinical use.

High purity suitable for analytical and biological research.
Multiple solid vial sizes available, including small research quantities.
Available as a ready-to-use 10 mM solution in DMSO for rapid testing.
Molecular weight 835.82 and formula C42H52Cl2N8O6 for precise calculations.
CAS number 1303533-81-4 for unambiguous identification.

Pricing & Availability

2,370

Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | 98.4% | C19H18ClN5O7S3 | 1 ML

Ceftiofur hydrochloride is a potent cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs). It exerts bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis, leading to cell lysis. Additionally, it possesses anti-inflammatory properties, inhibiting NF-κB and MAPKs, which reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This compound has been shown to improve survival rates in endotoxemia models.

Targets bacterial penicillin-binding proteins (PBPs)
Inhibits bacterial cell wall peptidoglycan synthesis
Induces bacterial cell lysis
Reduces secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6)
Inhibits phosphorylation of ERK, JNK, and p38
Blocks nuclear translocation of NF-κB p65
Improves survival in endotoxemia models
Cited in 4 scientific publications

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Alcohols and polyols

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Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cl-amidine hydrochloride | 1373232-26-8 | MFCD22201084 | 99.8% | 347.24 | C14H20Cl2N4O2 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Antalarmin hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-408124 Hydrochloride | 1431697-90-3 | 98.8% | C19H19ClF2N4O | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-269970 hydrochloride | 261901-57-9 | C18H29ClN2O3S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ribociclib hydrochloride | 1211443-80-9 | >99.9% | 471.00 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ravidasvir (hydrochloride) | 1303533-81-4 | MFCD32705191 | 99.9% | 835.82 | C42H52Cl2N8O6 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | 98.4% | C19H18ClN5O7S3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More