Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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3,451 – 3,465 of 6,672 results

3,451

Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG

Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.

Strengthens vascular contraction
Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
Increases Ca2+ in C2C12, HL1, and HepG2 cells
Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
Reduces cellular lipid content in 3T3-L1 cells
Reduces platelet-activating factor (Paf)-induced death in mice
Shows anti-hypotensive effects in orthostatic hypotension rat models
Relieves hypertension in spontaneously hypertensive rat models

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3,452

Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 98.4% | 25 MG

Moexipril hydrochloride is an orally active inhibitor of angiotensin-converting enzyme (ACE) that becomes effective after being hydrolyzed to moexiprilat (hydrochloride). This compound demonstrates significant antihypertensive and neuroprotective effects.

Orally active inhibitor of angiotensin-converting enzyme (ACE).
Becomes effective after hydrolysis to moexiprilat.
Exhibits antihypertensive and neuroprotective effects.
High potency against plasma ACE and purified ACE from rabbit lung.
Significantly reduces damaged neurons in a dose-dependent manner.
Attenuates Fe2+/3+-induced neurotoxicity.
Does not cause significant changes in apoptotic neurons.
Does not cross the blood-brain barrier.
Shows dose-dependent antihypertensive effects in various animal models.
Reduces infarct area on mouse brain surface.
Attenuates cortical infarct volume in rat brain.

Pricing & Availability

3,453

Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.3% | 274.79 | 10 MG

PhiKan 083 hydrochloride is a carbazole derivative designed to bind to the surface cavity and stabilize the Y220C p53 mutant, with a binding affinity (Kd) of 167 μM. It effectively slows down the thermal denaturation rate of the p53 mutant and has been shown to reduce cell viability in engineered variants of Ln229 cells. When used in combination with NSC 123127, it enhances pro-apoptotic activity across multiple Ln229 cell variants.

Binds to and stabilizes Y220C p53 mutant
Slows down thermal denaturation rate of p53 mutant
Reduces cell viability in engineered variants of Ln229 cells
Enhances pro-apoptotic activity when combined with NSC 123127

Pricing & Availability

3,454

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG

Melitracen hydrochloride is a research-grade tricyclic antidepressant hydrochloride salt supplied for laboratory use. It is used in pharmacological studies of monoamine neurotransmitter uptake and serotonergic (5-HT) receptor pathways. Provided as a solid for in vitro and preclinical research; not for human or veterinary use.

Tricyclic antidepressant hydrochloride salt.
Molecular formula C21H26ClN.
Molecular weight 327.89.
Purity >98.0% (HPLC).
Available as a solid powder, commonly in 200 MG quantities.
For research use only; not for human or veterinary use.

Pricing & Availability

3,455

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG

Azasetron hydrochloride is a benzamide derivative functioning as a potent and selective 5-HT3 receptor antagonist. It is utilized in studies concerning chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist
Used in studies for chemotherapy-induced nausea and vomiting (CINV)
Purity of 99.76%
Solid, white to off-white appearance
Effectively penetrates skin in in vivo studies
IC50 for 5-HT3 Receptor is 0.33 nM

Pricing & Availability

3,456

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG

Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to the estrogen receptor, and it also inhibits aromatase activity. It has potential for breast cancer study.

Key active metabolite of Tamoxifen (TAM).
Higher affinity and specificity to estrogen receptor.
Inhibits aromatase activity.
Potential for breast cancer study.
Approximately 100-fold more potent as an antagonist of the ER than tamoxifen.
Targets estrogen receptor α for degradation in breast cancer cells.
Blocks ERA transcriptional activity and inhibits estrogen-induced breast cancer cell proliferation.

Pricing & Availability

3,457

Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | 99.9% | 615.62 g/mol | C27H40Cl2N6O4S | 2 G

Fedratinib hydrochloride hydrate is the dihydrochloride monohydrate salt of fedratinib, an ATP-competitive, orally active and selective JAK2 inhibitor supplied for research use. The compound is provided as a solid (white to yellow) with high reported purity and is intended for in vitro and preclinical studies; not for human therapeutic use.

High purity (≈99.9%) as reported by supplier.
Molecular weight 615.62 g/mol; formula C27H40Cl2N6O4S.
Packaged in small-scale quantities, commonly available as 2 G.
Recommended storage: solid at 4°C; in solution -20°C to -80°C.
Potent JAK2 inhibitor with reported IC50 ≈3 nM, suitable for signaling and oncology research.

Pricing & Availability

3,458

Medchemexpress LLC SB-612111 hydrochloride | 371980-94-8 | 99.6% | 454.86 | 25 MG

SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist. It demonstrates high affinity for hORL-1 and selectivity for μ-, κ- and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in acute pain models.

Potent opiate receptor-like orphan receptor (ORL-1) antagonist
High affinity for hORL-1 (Ki=0.33 nM)
Exhibits selectivity for μ-, κ- and δ-receptors
Antagonizes pronociceptive action of Nociceptin
Had antihyperalgesic effects on carrageenan-induced rat paw

Pricing & Availability

3,459

Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | MFCD00868190 | 99.9% | 337.24 g·mol⁻¹ | C17H18Cl2N2O | 10 MG

Etifoxine hydrochloride is a non-benzodiazepine GABAergic compound used in research to modulate GABAA receptor activity. It is supplied as the hydrochloride salt for improved handling and solubility, and is commonly used in preclinical studies of anxiolytic and anticonvulsant effects.

Acts as a positive allosteric modulator of GABAA receptors
Hydrochloride salt form for enhanced solubility
High purity suitable for research applications
Available in small research pack sizes for preclinical work
Used in studies of anxiolytic and anticonvulsant pharmacology

Pricing & Availability

3,460

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG

Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine-derived, potent and selective vasopressin V2 receptor antagonist (reported IC50 ≈14 nM) used as a research chemical for studies of vasopressin signaling and conditions such as hyponatremia and SIADH. It is supplied as a white to off-white solid and is commonly available in small milligram quantities or as a DMSO solution for in vitro and pharmacology experiments. Molecular formula C27H30ClN3O2; molecular weight 464.0 g/mol; CAS 138470-70-9.

High purity suitable for research (≈99.9%)
Potent V2 receptor antagonist activity for pharmacology studies
Available in solid and DMSO solution formats
Compact packaging for small-scale experiments
Standard identifiers provided for traceability

Pricing & Availability

3,461

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML

Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.

Acts as a cannabinoid receptor type 1 (CB1) agonist
Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
Suppresses the transcriptional activity of the androgen receptor
Extracted from the bark of pine trees
Appears as a white to off-white solid
Store at -20°C in sealed conditions, away from moisture
For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture

Pricing & Availability

3,462

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.

Potent SUV39H2 inhibitor
Inhibits tumor growth in mouse xenograft models
Regulates production of γ-H2AX in cancer cells
Shows significant inhibition of tumor growth without detectable toxicity
Inhibits A549 cell growth with an IC50 of 0.67 μM
Exhibits growth suppressive effects in human cancer cell line derived xenograft models

Pricing & Availability

3,463

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG

SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG

Pricing & Availability

3,464

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme, with IC50 values of 33 μM for TET1 and 73 μM for TET2. It is valuable in the field of epigenetics and serves as a foundation for developing new therapeutics targeting DNA methylation and gene transcription.

Potent and selective cytosine-based inhibitor of TET enzyme.
Useful in epigenetics research.
Serves as a starting point for new therapeutics targeting DNA methylation and gene transcription.
Inhibitory activity is directly related to Cu(II) content; the Bobcat339-copper mixture shows significantly higher TET inhibition than either alone.
Significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells at 10 μM for 24 hours.

Pricing & Availability

3,465

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML

Azasetron hydrochloride (Y-25130 hydrochloride) is a benzamide derivative that functions as a potent and selective 5-HT3 receptor antagonist. It is currently under study for its application in treating chemotherapy-induced nausea and vomiting (CINV).

Potent and selective 5-HT3 receptor antagonist.
Used to study chemotherapy-induced nausea and vomiting (CINV).
Can effectively penetrate the skin and enter systemic circulation.

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Moexipril (hydrochloride) | 82586-52-5 | 98.4% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PhiKan 083 hydrochloride | 1050480-30-2 | 99.3% | 274.79 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | 99.9% | 615.62 g/mol | C27H40Cl2N6O4S | 2 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-612111 hydrochloride | 371980-94-8 | 99.6% | 454.86 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | MFCD00868190 | 99.9% | 337.24 g·mol⁻¹ | C17H18Cl2N2O | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.9% | 361.66 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More