Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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3,451 – 3,465 of 5,327 results

3,451

Medchemexpress LLC Berubicin hydrochloride | 293736-67-1 | 95.1% | 670.10 | 1 MG

Berubicin hydrochloride is an analog of Doxorubicin that can cross the blood-brain barrier. It inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). This product exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells. It can be used in the study of tumors related to the nervous system.

Crosses the blood-brain barrier
Inhibits P-gp and MRP1-mediated efflux
Suppresses glioblastoma multiforme (GBM)
Activates nuclear factor κB (NF-κB)
Induces apoptosis in neuroblastoma cells
More potent activity than Doxorubicin in activating NF-κB and inhibiting DNA synthesis
Prolongs survival time in intracranial orthotopic glioma models in mice

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3,452

Medchemexpress LLC mAChR-IN-1 (hydrochloride) | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MM 1ML

mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor antagonist (IC50 17 nM) provided for research use. It is offered as a solid and as a pre-made solution in DMSO, intended for in vitro pharmacology and receptor binding studies.

Potent mAChR antagonist (IC50 17 nM).
High purity: 99.6% (LCMS).
Chemical formula: C23H26ClIN2O2.
Molecular weight: 524.82 g/mol.
Physical appearance: white to off-white solid.
Available as solids (5-100 mg) and 10 mM solution in DMSO, 1 mL.
Supplied for research use only.

Pricing & Availability

3,453

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG

Nifenalol hydrochloride is a β-adrenergic receptor antagonist used in cardiac electrophysiology and pharmacology research. The compound is reported to induce early afterdepolarization (EAD) and is used to study arrhythmia and blood pressure-related effects.

Beta-adrenergic receptor antagonist activity
Induces early afterdepolarization useful for arrhythmia studies
Hydrochloride salt form for improved solubility
Molecular formula C11H17ClN2O3
Molecular weight 260.72
Available in small research pack sizes (e.g., 5 mg)
Intended for in vitro and in vivo research applications

Pricing & Availability

3,454

Medchemexpress LLC Indotecan (hydrochloride) | 1228035-68-4 | 99.8% | 514.95 | 25 MG

Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor. It has IC50s of 300, 1200, and 560 nM for P388, HCT116, and MCF-7 cell lines, respectively. This compound prevents the relaxation of supercoiled DNA and can be utilized for research on visceral leishmaniasis.

Potent Topoisomerase I inhibitor.
Effective in preventing relaxation of supercoiled DNA.
Can be used for research on visceral leishmaniasis.

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3,455

Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG

CP-640186 hydrochloride is an orally active and cell-permeable inhibitor of Acetyl-CoA carboxylase (ACC). It exhibits IC50 values of 53 nM for rat liver ACC1 and 61 nM for rat skeletal muscle ACC2. ACC is a crucial enzyme involved in fatty acid metabolism, responsible for synthesizing malonyl-CoA. This compound also promotes muscle fatty acid oxidation.

Orally active and cell-permeable.
Inhibits Acetyl-CoA carboxylase (ACC).
IC50s: 53 nM for rat liver ACC1, 61 nM for rat skeletal muscle ACC2.
Stimulates muscle fatty acid oxidation.

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3,456

Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG

Mefuparib hydrochloride is an orally active, substrate-competitive, and selective inhibitor of PARP1/2, with IC50 values of 3.2 nM and 1.9 nM respectively. It is known to induce apoptosis and exhibits significant anticancer activity both in vitro and in vivo.

Orally active.
Substrate-competitive and selective PARP1/2 inhibitor.
Induces apoptosis.
Possesses prominent anticancer activity in vitro and in vivo.

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3,457

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 10MM 1ML

Viloxazine hydrochloride is a research-grade small-molecule norepinephrine transporter inhibitor supplied for in vitro pharmacology and biochemical assays. The product is available as solid and as a ready-to-use 10 mM solution in DMSO (1 mL), providing a convenient format for concentration-controlled experiments.

Ready-to-use 10 mM solution in DMSO, 1 mL
Also available as solid in multiple mg pack sizes
High purity (98.9% typical)
Molecular formula C13H20ClNO3 and molecular weight ~273.75 g/mol
CAS number 35604-67-2 for unambiguous identification
SDS and storage instructions provided for safe handling

Pricing & Availability

3,458

Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | 99.8% | 337.24 | 10 MM 1 ML

Etifoxine hydrochloride is a non-benzodiazepine GABAergic compound. It acts as a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. It has demonstrated anxiolytic and anticonvulsant properties in rodents.

Acts as a positive allosteric modulator of GABAA receptors.
Demonstrates anxiolytic properties.
Demonstrates anticonvulsant properties.

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3,459

Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 250 MG

Noscapine hydrochloride is an orally active phthalideisoquinoline alkaloid with potent antitussive effects. It activates sigma opioid receptors and inhibits Bradykinin non-competitively. It also disrupts microtubule dynamics, leading to mitotic arrest and apoptosis. This compound exhibits anticancer, neuroprotective, and anti-inflammatory activities, and can cross the blood-brain barrier.

Activates sigma opioid receptors
Non-competitive Bradykinin inhibitor
Disrupts microtubule dynamics
Induces mitotic arrest and apoptosis
Exhibits anticancer activity
Exhibits neuroprotective activity
Exhibits anti-inflammatory activities
Capable of crossing the blood-brain barrier

Pricing & Availability

3,460

Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.

Inhibits human TXNIP promoter activity in INS-1 cells.
Decreases TXNIP mRNA and protein levels in INS-1 cells.
Blocks polymerase II binding to the E-box motif of the TXNIP promoter.
Reduces glucagon secretion in TC1-6 cells.
Inhibits glucagon-induced glucose output from primary hepatocytes.
Decreases glucagon secretion and action, and blocks hepatic glucose output in vivo.
Well tolerated in male C57BL/6J mice.
Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.

Pricing & Availability

3,461

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML

Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal aromatase inhibitor that effectively inhibits estrogen production. It is intended for research use only and not for patient use.

Potent and selective aromatase inhibitor with an IC50 of 6.4 nM.
Inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM.
Can suppress the synthesis of other cytochrome P-450 dependent steroids at higher doses.
Prevents the development of spontaneous mammary neoplasms in female rats.
Slows the development of pituitary pars distalis adenomas.
Reduces the incidence of spontaneous hepatocellular tumors.
Reduces parasite burden in male and female mice by 70%.

Pricing & Availability

3,462

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML

AMXI-5001 hydrochloride is a potent, orally active, and dual PARP1/2 and microtubule polymerization inhibitor. It shows selective antitumor cytotoxicity across a wide range of human cancer cells with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors, and can induce complete regression of established tumors, including very large ones.

Potent and orally active
Dual PARP1/2 and microtubule polymerization inhibitor
Selective antitumor cytotoxicity across a wide range of human cancer cells
Significantly lower IC50s compared to existing clinical PARP1/2 inhibitors
Induces complete regression of established tumors

Pricing & Availability

3,463

Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML

DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF) with an IC50 of 698 nM. It significantly inhibits leukemia cell proliferation in human leukemia MV-4-11 cells (EC50 120 nM, IC50 0.89 μM). The compound decreases downstream oncogene expression and c-Myc protein levels, with minimal effects on normal cells. Intended for research use only.

Inhibits bromodomain PHD finger transcription factor (BPTF)
IC50 of 698 nM against BPTF
Inhibits leukemia cell proliferation
Decreases oncogene expression and c-Myc protein
Minimal effects on normal cells
Off-white to light yellow solid appearance
Molecular weight: 433.95
Chemical formula: C20H24ClN5O2S

Pricing & Availability

3,464

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 1 ML

Melitracen hydrochloride is a research-grade small molecule antidepressant and anxiolytic agent supplied for in vitro pharmacology, mechanism-of-action studies, and analytical reference. The material is provided with solubility and stock-solution guidance, and recommended storage conditions for both solid and solution forms.

High purity of 99.8%.
CAS number 10563-70-9, formula C21H26ClN, molecular weight 327.89 g/mol.
Available as solid samples and as a pre-made 10 mM solution (1 mL) in DMSO.
Soluble in DMSO and water at up to 100 mg/mL; ultrasonic assistance may be required.
Storage: solid at 4°C; in solution store at -80°C up to 6 months or -20°C up to 1 month.
Includes stock solution preparation guidance for common concentrations.

Pricing & Availability

3,465

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG

Inhibits human TXNIP promoter activity and reduces TXNIP mRNA and protein levels in INS-1 cells.
Lowers glucagon secretion in TC1-6 cells and decreases glucagon secretion and action in vivo.
Reduces glucagon-induced glucose output from primary hepatocytes and blocks hepatic glucose output in vivo.
Reverses obesity- and Streptozotocin (STZ)-induced diabetes and hepatic steatosis in mice.
Orally bioavailable.
Well-tolerated in male C57BL/6J mice.

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC Berubicin hydrochloride | 293736-67-1 | 95.1% | 670.10 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC mAChR-IN-1 (hydrochloride) | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 260.72 | C11H17ClN2O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Indotecan (hydrochloride) | 1228035-68-4 | 99.8% | 514.95 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CP-640186 (hydrochloride) | 591778-70-0 | C30H36ClN3O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.75 g/mol | C13H20ClNO3 | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | 99.8% | 337.24 | 10 MM 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMXI-5001 hydrochloride | 98.1% | C25H21ClFN5O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More