Alcohols and polyols
- (1)
- (55)
- (347)
- (39)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (153)
- (1)
- (65)
- (27)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
- (4)
- (1)
- (2)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
- (2)
- (8)
- (2)
- (3)
- (3)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (1)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (5)
- (3)
- (2)
- (1)
- (2)
- (1)
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- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (27)
- (2)
- (1)
- (2)
- (1)
- (4)
- (3)
- (2)
- (4)
- (3)
- (2)
- (7)
- (2)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (21)
- (16)
- (1)
- (2)
- (20)
- (2)
- (2)
- (3)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
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- (2)
- (2)
- (2)
- (2)
- (9)
- (6)
- (8)
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- (1)
- (1)
- (1)
- (1)
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- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (273)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (6)
- (3)
- (1)
- (4)
- (21)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (704)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (3)
- (4)
- (33)
- (2)
- (31)
- (2)
- (3)
- (3)
- (3)
- (11)
- (3)
- (2)
- (1)
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- (3)
- (2)
- (3)
- (1)
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- (3)
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- (2)
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- (7)
- (1)
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- (2)
- (1)
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- (2)
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- (2)
- (1)
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- (1)
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- (2)
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- (1)
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- (2)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (1)
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- (1)
- (2)
- (5)
- (2)
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- (2)
- (2)
- (3)
- (2)
- (2)
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- (2)
- (2)
- (2)
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- (3)
- (2)
- (2)
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- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
- (3)
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- (3)
- (2)
- (1)
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- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
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- (2)
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- (1)
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- (2)
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- (1)
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- (2)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (1)
- (1)
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Filtered Search Results
Chemscene CHEMSCENE
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5000579742 PCPA METHYL ESTER HYDROCHLO 1G
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Medchemexpress LLC Leonurine hydrochloride | 24735-18-0 | 347.79 | 50 MG
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Leonurine hydrochloride | 24735-18-0 | 347.79 | 50 MG
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG
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Dopexamine hydrochloride | 86484-91-5 | 429.42 | 10 MG
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Medchemexpress LLC Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Medchemexpress LLC VU0453379 hydrochloride | 1638646-27-1 | 99.0% | 471.03 | 100 MG
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM. It is for research use only and not sold to patients. The product is described as a highly selective and CNS penetrant positive allosteric modulator.
- Highly selective
- CNS penetrant positive allosteric modulator
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Medchemexpress LLC P-F-HHSiD (hydrochloride) | 175615-76-6 | 99% | 386.02 | 1 MG
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p-F-HHSiD (hydrochloride) is a selective M3 mAChR antagonist. It blocks Acetylcholine-mediated vasodilatation in human umbilical vein endothelial cells (HUVECs). This product is intended for laboratory use.
- Selective M3 mAChR antagonist
- Blocks Acetylcholine-mediated vasodilatation
- Suitable for laboratory research
- Solid appearance
- Stable under recommended storage conditions
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Medchemexpress LLC Fadrozole hydrochloride (CGS 16949A) | 102676-31-3 | 99.9% | C14H14ClN3 | 50 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM and progesterone production with an IC50 of 120 μM. Higher doses can suppress the synthesis of other cytochrome P-450 dependent steroids to varying degrees.
- Potent and selective aromatase inhibitor.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows development of pituitary pars distalis adenomas and reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
- Augments Interleukin-6 (IL-6) serum levels and production by splenocytes.
- Nonsteroidal option for aromatase inhibition.
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Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | 99.9% | 615.6 g/mol | C27H40Cl2N6O4S | 1 ML
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Fedratinib (hydrochloride hydrate) is the dihydrochloride monohydrate salt of fedratinib, a potent ATP-competitive JAK2 inhibitor used for research into JAK2 signaling and myeloproliferative disorders. Supplied as a ready-to-use solution, it supports biochemical and cell-based assays requiring a high-quality JAK2 inhibitor.
- Potent JAK2 inhibitor with low-nanomolar potency
- Dihydrochloride monohydrate salt form for improved solubility
- Provided as a pre-made 10 mM solution for immediate use
- High chemical purity (99.9%) for reliable experimental results
- Suitable for biochemical and cell-based assay applications
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Medchemexpress LLC Simufilam hydrochloride | 2480226-07-9 | 99.9% | 295.81 | 10 MG
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Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. It restores NMDAR signaling and Arc expression, inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, and reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. It can be used for research of Alzheimer's disease.
- Acts as an orally active FLNA modulator
- Restores NMDAR signaling and Arc expression
- Inhibits overactive mTOR signaling by restoring normal FLNA conformation
- Improves insulin sensitivity
- Reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation
- Useful for Alzheimer's disease research
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Medchemexpress LLC Fendiline hydrochloride | 13636-18-5 | 99.8% | 351.91 | 100 MG
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Fendiline hydrochloride is a diphenylalkylamine type of antianginal agent that functions as an L-type calcium channel blocker and selective K-Ras inhibitor. It inhibits K-Ras plasma membrane localization, thereby blocking K-Ras signal output and the proliferation of various cancer cell lines. Additionally, it acts as a STING agonist, capable of inhibiting the growth of multiple refractory cold tumors.
- Functions as an L-type calcium channel blocker
- Acts as a selective K-Ras inhibitor
- Inhibits K-Ras plasma membrane localization
- Blocks proliferation of pancreatic, colon, lung, and endometrial cancer cell lines
- Acts as a STING agonist capable of inhibiting tumor growth
- Purity: 99.78%
- Molecular weight: 351.91
- Formula: C23H26ClN
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | MFCD04038020 | 98.43% | C19H18ClN5O7S3 | 100 MG
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Ceftiofur hydrochloride is an inhibitor of bacterial cell wall synthesis that targets bacterial penicillin-binding proteins (PBPs). It exhibits anti-inflammatory effects in endotoxemia. Its bactericidal action stems from inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Additionally, Ceftiofur hydrochloride can inhibit the activation of NF-κB and MAPKs, which consequently reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.
- Targets bacterial penicillin-binding proteins (PBPs).
- Exhibits bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis.
- Leads to bacterial cell lysis.
- Possesses anti-inflammatory properties by inhibiting NF-κB and MAPK activation.
- Reduces the secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6).
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Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 25 MG
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Dopexamine hydrochloride is a β2 adrenergic receptor agonist and a dopamine analogue. It exhibits agonist activity at β2 and dopaminergic receptors, attenuating systemic inflammatory response, reducing tissue leukocyte infiltration, and protecting against organ injury. It can reduce the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without significantly altering systemic hemodynamics.
- Agonist activity at β2 and dopaminergic receptors
- Attenuates systemic inflammatory response
- Reduces tissue leukocyte infiltration
- Protects against organ injury
- Stimulates β-adrenergic and dopamine 1 and 2 receptors
- Confers vasodilatory effects
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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG
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Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.
- Potent CCR5 antagonist
- Effective against wild-type R5 HIV-1 strains
- Suppresses HIV-1MDR variants
- Binds to CCR5 with high affinity
- Suppresses R5 HIV-1 viremia in animal models
- Investigated in clinical trials for HIV infection
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Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG
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Adrogolide hydrochloride is a research-grade prodrug converted rapidly in plasma to the dopamine D1 receptor agonist A-86929. Supplied as the hydrochloride salt, it is intended for laboratory research use only and is provided in pre-weighed quantities for assay preparation.
- High purity (≈99.6%) suitable for research applications.
- Molecular weight 435.96 and formula C22H26ClNO4S.
- Available in pre-weighed small quantities for in vitro and in vivo studies.
- Soluble in DMSO for assay preparation.
- Acts as a prodrug to the D1 receptor agonist A-86929.
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Medchemexpress LLC Cct241533 hydrochloride | 1431697-96-9 | 98.55% | 478.94 | 50 MG
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CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM. It exhibits minimal cross-reactivity against a panel of kinases at 1 μM. X-ray crystallography confirms its binding to CHK2 in the ATP pocket. The compound blocks CHK2 activity in human tumor cell lines in response to DNA damage, significantly enhancing the cytotoxicity of two structurally distinct PARP inhibitors. Clear induction of the pS516 CHK2 signal by PARP inhibitor alone is abolished by CCT241533. The cytotoxicity (GI50) in HT-29, HeLa, and MCF-7 cells is 1.7, 2.2, and 5.1 μM, respectively.
- Potent and selective CHK2 inhibitor (IC50=3 nM)
- 63-fold selectivity over CHK1 (IC50=190 nM)
- Low hERG inhibition (IC50=22 μM)
- Blocks CHK2 activity in human tumor cell lines in response to DNA damage
- Enhances cytotoxicity of PARP inhibitors
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