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Filtered Search Results
Medchemexpress LLC Illudin S | 1149-99-1 | MFCD00870487 | 99.8% | 264.32 | C15H20O4 | 5MG
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Illudin S is a cytotoxic natural sesquiterpene supplied for research use; it exhibits anti-tumor and antiviral activity and is reported to possess genotoxic properties, including blockage of the G1-S phase transition in human leukemia cells.
- High purity (99.8%) suitable for analytical and cellular studies.
- Supplied as a small research quantity (5 mg) in powder form.
- Solid, white to yellow appearance for straightforward handling.
- Molecular formula C15H20O4; molecular weight 264.32 g/mol.
- Documented genotoxic and cell-cycle blocking activity in vitro.
- Storage guidance: powder -20°C for long term; in solvent -80°C (short term).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Rac-zevaquenabant | 1610420-28-4 | 99.2% | 547.98 | C25H21ClF3N5O2S | 5 MG
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(Rac)-Zevaquenabant is a research small molecule described as a cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS) antagonist with reported CB1R Ki ~5.7 nM. It is used in preclinical studies, including liver fibrosis research, and is supplied as a solid or as a ready-to-use solution in DMSO.
- Potent CB1R antagonist with reported Ki of 5.7 nM.
- Also antagonizes inducible nitric oxide synthase (iNOS), useful for dual-pathway studies.
- High purity: 99.2%.
- Available as solid and as a 10 mM solution in DMSO.
- Molecular weight 547.98; formula C25H21ClF3N5O2S.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (up to 6 months).
- For research use only; not for human or clinical use.
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Medchemexpress LLC TD52 dihydrochloride | 00-00-0 | 99.6% | 433.33 g/mol | C24H18Cl2N4 | 5 MG
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TD52 dihydrochloride is a research-grade small-molecule inhibitor of cancerous inhibitor of protein phosphatase 2A (CIP2A). An Erlotinib derivative, it is orally active and induces apoptosis in triple-negative breast cancer cells by modulating the CIP2A/PP2A/p-Akt signaling pathway. Supplied as the dihydrochloride salt, the compound includes an alkyne group that enables click-chemistry applications.
- High purity suitable for research applications (99.6%).
- Available in small research pack sizes, including 5 mg.
- Supplied as solid powder and as a 10 mM solution in DMSO.
- Targeted for oncology and cell-signaling studies involving CIP2A/PP2A.
- Compatible with copper-catalyzed azide-alkyne cycloaddition reactions.
- Molecular formula C24H18Cl2N4; molecular weight 433.33 g/mol.
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Medchemexpress LLC Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-[2-[9-[(4-fluorophenyl)methyl]-5,6,8,9-tetrahydro... | 1354805-08-5 | 99.9% | 461.53 g/mol | C27H28FN3O3 | 5 MG
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ONO-8430506 is a potent, orally bioavailable autotaxin (ATX/ENPP2) inhibitor used for biochemical assays and preclinical studies. It exhibits low-nanomolar enzymatic potency and has demonstrated in vivo activity in rodent tumor models, with established solubility and storage data for laboratory use.
- Potent ATX inhibition with low-nanomolar IC50 values in enzymatic assays.
- IC90 of 100 nM for ATX activity in mouse plasma.
- Orally bioavailable and effective in preclinical tumor models.
- Documented solubility in DMSO and multiple in vivo formulation options.
- High supplied purity and specified storage conditions for stability.
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Medchemexpress LLC 1-[4-[(2S)-2-(morpholin-4-ylmethyl)pyrrolidin-1-yl]sulfonylphenyl]-3-[4-(trifluoromethyl)phenyl]urea | 2230496-99-6 | 99.9% | 512.55 | C23H27F3N4O4S | 5 MG
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ZL0590 is a potent, orally active small-molecule inhibitor selective for the BRD4 BD1 bromodomain. It has an IC50 of approximately 90 nM against human BRD4 BD1 and demonstrates anti-inflammatory efficacy in preclinical models, making it suitable for research into bromodomain biology and inflammatory disease mechanisms.
- Potent BRD4 BD1 inhibition (IC50 ≈ 90 nM)
- Selective for BD1 over other bromodomains
- Demonstrated anti-inflammatory activity in animal models
- Appropriate for in vitro and in vivo research applications
- Soluble in DMSO for solution preparation
- High chemical purity (~99.9%)
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Medchemexpress LLC Oritinib | 2035089-28-0 | 99.6% | 539.67 g/mol | C31H37N7O2 | 5 MG
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Oritinib is an irreversible, third-generation EGFR tyrosine kinase inhibitor developed to overcome T790M-mediated resistance. Supplied as a high-purity solid research compound, it is used in preclinical biochemical and cellular studies to interrogate EGFR signaling and resistance mechanisms.
- Irreversible third-generation EGFR inhibitor.
- Active against T790M resistance mutations.
- High chemical purity (99.6%).
- Provided as a solid suitable for dosing and formulation.
- Applicable to biochemical and cellular assays.
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Medchemexpress LLC N-desethyl sunitinib hydrochloride | 99.1% | 406.88 | C20H24ClFN4O2 | 5 MG
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N-desethyl sunitinib hydrochloride is the N-desethyl metabolite of the tyrosine kinase inhibitor sunitinib, supplied as a solid hydrochloride salt for laboratory research. It is provided in small, accurately weighed packages for use as a reference standard or in biochemical and cell-based kinase studies.
- High purity (99.1%).
- Supplied as a solid hydrochloride salt, yellow to brown.
- Available in multiple small package sizes for research use.
- Suitable as a metabolite reference in kinase inhibitor and pharmacokinetic studies.
- Stable when stored sealed at 4°C; long-term storage in solvent at -80°C.
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Medchemexpress LLC O=C(NC1=CC=CC(CN(C(C=CS2)=C2C(N3CCC)=O)C3=O)=C1)CC4=CC=CC=C4 | 2098776-03-3 | 98.4% | 433.52 g·mol⁻¹ | C24H23N3O3S | 5 MG
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FEN1-IN-SC13 is a small-molecule inhibitor of flap endonuclease 1 (FEN1) that interferes with DNA replication and repair and has reported antitumor activity in vitro and in cells. It is supplied for research use as a characterized solid or as a 10 mM solution in DMSO, with documented purity and storage recommendations.
- Potent FEN1 inhibition with reported antitumor activity.
- Purity 98.42%.
- Chemical formula C24H23N3O3S; molecular weight 433.52 g·mol⁻¹.
- Available as solid (5-500 mg) and 10 mM 1 mL solution in DMSO.
- Store powder at -20°C (long term) or 4°C (short term); store solutions at -80°C or -20°C as recommended.
- Intended for research use only.
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Medchemexpress LLC Carboxylesterase-IN-3 | 2764748-92-5 | MFCD34676411 | 98.3% | 313.16 | C11H6Cl2N4OS | 5 MG
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Carboxylesterase-IN-3 is a research-grade small molecule inhibitor of the carboxylesterase Notum enzyme, reported as compound 4y with an IC50 ≤ 10 nM. It is intended for biochemical and cellular studies of Wnt signaling and related disease research.
- Potent Notum inhibitor (IC50 ≤ 10 nM).
- High purity, 98.3%.
- Molecular weight 313.16 g/mol; formula C11H6Cl2N4OS.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Available in multiple milligram pack sizes and as DMSO solutions.
- Powder storage: -20°C for long term; in solvent: -80°C recommended.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Abd957 | 3007772-60-0 | 98.1% | 627.68 g/mol | C27H36F3N7O5S | 5 MG
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ABD957 is a selective, covalent inhibitor of the ABHD17 family of depalmitoylases, reported to inhibit ABHD17B with an IC50 of 0.21 μM; it is supplied for research use with analytical data provided for confirmation.
- Selective covalent inhibition of ABHD17 depalmitoylases with reported IC50 0.21 μM for ABHD17B.
- Reported purity supports biochemical and cellular assays.
- Characterized molecular weight and chemical formula for analytical verification.
- Available in multiple small-scale quantities suitable for laboratory studies.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide | 2871872-79-4 | 99.9% | 378.49 | C18H26N4O3S | 5 MG
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DS96432529 is a small-molecule cyclin-dependent kinase 8 (CDK8) inhibitor reported to have potent, orally active bone anabolic effects. It is supplied for research use and is characterized by a molecular formula of C18H26N4O3S, a molecular weight of 378.49 g/mol, and a CAS number of 2871872-79-4. Analytical documentation and a certificate of analysis are available.
- Potent CDK8 inhibition with bone anabolic activity.
- Orally active pharmacological profile in reported studies.
- High purity (99.9%) suitable for research applications.
- Available in small research pack sizes, including 5 mg.
- Characterized by formula C18H26N4O3S and molecular weight 378.49 g/mol.
- Analytical documentation available (COA, H NMR, LC-MS).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (Z)-lanoconazole | 101529-65-1 | MFCD00865590 | 99.3% | 319.8 g/mol | C14H10ClN3S2 | 5 MG
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(Z)-Lanoconazole is an imidazole-class antifungal research compound (CAS 101529-65-1) supplied for laboratory use. It is provided as a high-purity solid and as pre-formulated DMSO solutions for in vitro antifungal assays and biochemical studies. Typical package sizes include low-milligram vials suitable for research workflows.
- Imidazole-class antifungal compound for research applications.
- High purity (~99.3%) appropriate for analytical and biological assays.
- Available as solid powder and as 10 mM solution in DMSO.
- Supplied in small-scale vials for experimental workflows.
- Product documentation includes COA and SDS for quality and safety.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 5-cyclopropyl-N-cyclopropylsulfonyl-2-fluoro-4-[(6-methylspiro[2.5]octan-6-yl)methoxy]benzamide | 1494585-79-3 | 99.2% | 10MG
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5-cyclopropyl-N-cyclopropylsulfonyl-2-fluoro-4-[(6-methylspiro[2.5]octan-6-yl)methoxy]benzamide | 1494585-79-3 | 99.2% | 10MG
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Medchemexpress LLC Zalunfiban dihydrochloride | 2815778-41-5 | 99.1% | 5 MG
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Zalunfiban dihydrochloride is a potent, selective platelet αIIbβ3 antagonist used in research applications such as myocardial infarction studies. It is supplied as the dihydrochloride salt with high reported purity and is typically used in biochemical and pharmacological assays.
- Potent αIIbβ3 antagonist (IC50 = 45 nM).
- Reported purity 99.07%.
- Molecular formula C16H20Cl2N8O2S, molecular weight 459.35 g/mol.
- Available in small pack sizes suitable for research (for example, 5 mg).
- Soluble in DMSO; supplied as the dihydrochloride salt.
- Used in myocardial infarction and platelet aggregation research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC QTX125 TFA | 2989537-78-0 | 99.9% | 10 MG
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QTX125 TFA is the trifluoroacetic acid salt of QTX125, a potent and highly selective histone deacetylase 6 (HDAC6) inhibitor with reported antitumor activity. It is supplied as a high-purity research compound for biochemical and in vivo studies.
- Potent, selective HDAC6 inhibitor.
- High purity: 99.9%.
- Molecular weight: 531.44 g/mol; formula: C25H20F3N3O7.
- Solubility: soluble in DMSO (125 mg/mL), insoluble in water.
- Storage: store sealed at 4°C; stock solutions -80°C (6 months), -20°C (1 month).
- Available in small research sizes including 10 MG.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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