Eliglustat-d4 is the deuterium labeled Eliglustat. Eliglustat is a specific, potent, and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- It is the deuterium labeled version of Eliglustat.
- It can be used as a tracer.
- It can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.