Halophenols
Medchemexpress LLC Olpasiran sodium | 2225856-03-9 | C490H610F11N164Na42O306P41S7 | 1 MG
Olpasiran sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. It directly inhibits LPA messenger RNA translation in hepatocytes and potently reduces Lp(a) concentration. It can be used for the research of cardiovascular disease, such as atherosclerosis.
- N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted small interfering RNA.
- Potently reduces lipoprotein(a) concentration by directly inhibiting LPA messenger RNA translation.
- Demonstrated efficacy in silencing LPA reporter gene expression in human hepatocellular carcinoma cells.
- Achieves sustained and significant reductions in serum lipoprotein(a) levels in preclinical animal models.
- Potential application in cardiovascular disease research, specifically atherosclerosis.
Medchemexpress LLC Fondaparinux sodium | 114870-03-0 | 98.0% | 1 ML
Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor intended for research use only. This compound exhibits high purity and is available as a white to off-white solid.
- Antithrombin-dependent factor Xa inhibitor
- For research use only
- High purity of 98.0%
- Appears as a white to off-white solid
- Soluble in H2O
- Exhibits a linear, dose-dependent pharmacokinetic profile
- Features 100% bioavailability, rapid onset of action, and a half-life of 14 to 16 hours
- Does not affect prothrombin time, activated partial thromboplastin time, platelet function, or aggregation
Medchemexpress LLC Fondaparinux sodium | 114870-03-0 | 98.0% | 1 MG
Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor and the first agent of a new class of anticoagulants that selectively targets factor Xa.
- Antithrombin-dependent factor Xa inhibitor
- First agent of a new class of anticoagulants
- Selectively targets factor Xa
- Purity: 98.0%
- Molecular weight: 1728.08
- Appearance: Solid, white to off-white
- Solubility: 125 mg/mL (72.33 mM) in H2O (requires ultrasonic)
- Shows a linear, dose-dependent pharmacokinetic profile with 100% bioavailability
- Rapid onset of action with a half-life of 14 to 16 hours
- Does not affect prothrombin time, activated partial thromboplastin time, platelet function, or aggregation
Medchemexpress LLC Probenecid sodium | 23795-03-1 | MFCD01661360 | 99.4% | 307.34 | C13H18NNaO4S | 10 G
Probenecid sodium is the sodium salt of probenecid supplied for laboratory research. It acts as a TRPV2 agonist and an inhibitor of organic-anion transporters, provided as a white to off-white solid characterized by CAS 23795-03-1 and molecular formula C13H18NNaO4S.
- Sodium salt form with improved water solubility.
- Active as a TRPV2 agonist and organic-anion transport inhibitor.
- High purity (99.4%).
- Available in research-scale pack sizes, including 10 G.
- Suitable for analytical and biological assays.
Medchemexpress LLC Probenecid sodium | 23795-03-1 | MFCD01661360 | 99.4% | 307.34 | C13H18NNaO4S | 25 G
Probenecid sodium is the sodium salt of probenecid used in cell biology and pharmacology research as a selective TRPV2 agonist and an inhibitor of pannexin 1 channels. It is supplied as a high-purity research reagent with defined molecular properties and storage recommendations for stability.
- Acts as a selective TRPV2 agonist and pannexin 1 inhibitor.
- High purity (reported 99.4%).
- Available in laboratory-scale package sizes, including 25 G.
- Chemical formula C13H18NNaO4S; molecular weight 307.34 g/mol.
- Recommended to store sealed and away from moisture; long-term stability in solvent at -80°C.
Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | 99.2% | 308.37 g/mol | C19H20N2O2 | 25 MG
UCM 608 (2-Phenylmelatonin) is a potent, high-affinity melatonin (MT) membrane receptor agonist provided as a purified small-molecule standard for in vitro pharmacology and assay development. It is intended for research use only and has documented binding data for MT1 and MT2.
- High affinity for MT1 and MT2 (pKi 10.7 and 10.4).
- High purity (99.18%).
- Well characterized small molecule with formula C19H20N2O2 and molecular weight 308.37 g/mol.
- Supplied in small quantities and solution formulations suitable for assays.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | 99.2% | 308.37 g/mol | C19H20N2O2 | 5 MG
2-Phenylmelatonin is a high-affinity melatonin membrane receptor agonist used for research applications. It demonstrates potent binding to MT1 and MT2 receptors and is supplied as a high-purity powder suitable for in vitro and in vivo studies.
- High affinity for MT1 and MT2 receptors (pKi 10.7, 10.4).
- High purity (~99.2%).
- Molecular weight 308.37 g/mol.
- Available in small research quantities (for example, 5 mg).
- Soluble in DMSO (50 mg/mL) and compatible with common in vivo formulations.
- Stable as powder when stored at -20°C for long-term storage.
- Intended for research use only.
Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | MFCD00673896 | 99.2% | 308.37 g/mol | C19H20N2O2 | 1 ML
UCM 608 (2-phenylmelatonin) is a high-affinity melatonin (MT) membrane receptor agonist used in receptor pharmacology and signaling studies. It is supplied as solid material or as a ready-to-use 10 mM solution in DMSO for use in binding and functional assays.
- High affinity for MT1 and MT2 receptors (reported pKi values: MT1 10.7, MT2 10.4).
- High purity suitable for research (99.18%).
- Available as a 10 mM solution in DMSO for immediate use.
- Also available in multiple solid quantities for dose flexibility.
- Well characterized chemically (C19H20N2O2; molecular weight 308.37 g/mol; CAS 151889-03-1).
Medchemexpress LLC Probenecid (sodium) | 23795-03-1 | MFCD01661360 | 99.4% | 307.34 g/mol | C13H18NNaO4S | 1 ML
Probenecid sodium is the sodium salt of probenecid supplied for research use. It is used as a TRPV2 agonist and in assays involving pannexin 1 channel inhibition. The product is offered as a solid or as a ready-to-use solution for laboratory applications.
- Sodium salt form suitable for research applications.
- Available as a 10 mM solution in DMSO (1 mL) or as a solid for reconstitution.
- High purity (~99.4%).
- Molecular formula C13H18NNaO4S, molecular weight 307.34 g/mol.
- Acts as a TRPV2 agonist and inhibits pannexin 1 channels.
- Supplied with safety data sheet and product documentation.
Medchemexpress LLC Valnivudine hydrochloride | 956483-03-7 | 98.99% | 534.04 | 1 ML
FV-100 is a potent, selective, and orally active anti-varicella zoster virus agent. It is a proagent of CF-1743 and demonstrates very low toxicity *in vivo*.
- Potent anti-varicella zoster virus agent
- Selective activity
- Orally active
- Proagent of CF-1743
- Very low toxicity *in vivo*
Medchemexpress LLC (20R)-Ginsenoside Rg3 | 38243-03-7 | 785.01 | 1 ML
(20R)-ginsenoside Rg3, also known as (20R)-Propanaxadiol, is one of the active compounds found in ginseng root. It is recognized for its ability to inhibit angiogenesis and possesses anti-carcinogenic and antimetastatic effects.
- Inhibits the proliferation of human umbilical vein endothelial cells (HUVEC) with an IC50 of 10 nM.
- Dose-dependently suppresses capillary tube formation on Matrigel.
- Significantly attenuates VEGF-induced chemoinvasion of HUVEC and ex vivo microvascular sprouting.
- Remarkably abolishes bFGF-induced angiogenesis in an in vivo Matrigel plug assay.
- Shows anti-fatigue effects in mice via intranasal administration.
Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | MFCD00673896 | 99.2% | 308.37 g/mol | C19H20N2O2 | 50 MG
2-phenylmelatonin is a high-affinity melatonin membrane receptor agonist used in receptor pharmacology studies; it displays pKi values of 10.7 (MT1) and 10.4 (MT2) and is supplied as a high-purity solid for research applications.
- High-affinity melatonin receptor agonist with pKi MT1 10.7 and MT2 10.4.
- Molecular formula C19H20N2O2 and molecular weight 308.37 g/mol.
- CAS number 151889-03-1 for unambiguous identification.
- High purity (99.18%) solid suitable for in vitro and in vivo studies.
- Soluble in DMSO at 50 mg/mL; in vivo formulations reported at ≥1 mg/mL with common vehicles.
- Store powder at -20°C for long-term stability; store solutions at -80°C when indicated.
Medchemexpress LLC 2-phenylmelatonin | 151889-03-1 | MFCD00673896 | 99.2% | 308.37 g/mol | C19H20N2O2 | 10 MG
UCM 608 (2-Phenylmelatonin) is a high-affinity melatonin (MT) receptor agonist supplied as a purified solid for laboratory research. It binds MT1 and MT2 receptors with reported pKi values of 10.7 and 10.4, respectively, and is used in pharmacology and receptor-binding studies. Handle and store according to safety data and laboratory protocols.
- High affinity for MT1 and MT2 receptors.
- Reported pKi values: MT1 10.7, MT2 10.4.
- Molecular formula C19H20N2O2.
- Molecular weight 308.37 g/mol.
- Purity approximately 99.18% (reported).
- Solid, off-white to yellow appearance.
- Store powder at -20°C or 4°C per stability guidance.
- Intended for research use only.
Medchemexpress LLC Probenecid sodium | 23795-03-1 | MFCD01661360 | 99.4% | 307.34 g/mol | C13H18NNaO4S | 5 G
Probenecid sodium is the sodium salt of probenecid, a selective TRPV2 agonist that also inhibits pannexin 1 channels. Supplied as a white to off-white solid for research use only. Typical analytical purity is 99.4% and the compound is suitable for preparing concentrated DMSO stocks.
Medchemexpress LLC Probenecid (sodium) | 23795-03-1 | MFCD01661360 | 99.4% | 307.34 g/mol | C13H18NNaO4S | 100 G
Probenecid sodium is the sodium salt of probenecid provided as a research reagent for use in biochemical and pharmacological studies, including transient receptor potential vanilloid 2 (TRPV2) channel activation assays. The material is supplied with supporting analytical documentation for laboratory handling and safety and is not intended for human use.
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