Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical Cobicistat, Purity: ≥98%, CAS: 1004316-88-4, 5 mg
An inhibitor of CYP3A (IC50s = 30-285 nM for CYP3A metabolism of various HIV protease inhibitors); selective for CYP3A over other CYP isomers (IC50 = >25 μM for CYP1A2, 2C8, 2C9, and 2C19); does not inhibit HIV-1 protease (IC50 = >30 μM) or affect HIV replication in MT-2 cells (EC50 = >30 μM)
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Medchemexpress LLC Ethoxyacetic acid | 627-03-2 | MFCD00004310 | 98.0% | 104.11 g/mol | C4H8O3 | 10 G
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Ethoxyacetic acid is an endogenous metabolite supplied as a high-purity analytical standard for research use. It is provided as a colorless to light-yellow liquid (C4H8O3) with characterized molecular weight and documented quality data, intended for biochemical, analytical, and formulation studies.
- Purity 98.0% (NMR) for analytical reliability.
- Molecular weight 104.11 g/mol; formula C4H8O3 for accurate calculations.
- High solubility in DMSO (75 mg/mL) for easy preparation of stock solutions.
- Available in multiple liquid package sizes suitable for lab-scale use.
- Batch-specific certificate of analysis and SDS available for quality control.
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TARGETMOL CHEMICALS INC ALVIMOPAN 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Alvimopan (LY 246736) is a synthetic trans-3 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration this agent binds to mu-opioid receptors in the gut thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone. purity: 99%
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Medchemexpress LLC FGFR-3 Human HEK29 2ug
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Recombinant human FGFR-3 alpha (IIIc) extracellular domain fused to a human Fc, expressed in HEK293 cells and supplied as a lyophilized powder for research use. The protein is validated for bioactivity and quality, with low endotoxin and high purity to support biochemical and cell-based assays.
- Human extracellular FGFR-3 domain fused to human Fc for improved stability and detection.
- Expressed in HEK293 cells to provide mammalian post-translational modifications.
- Lyophilized formulation for long-term storage and transport.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Endotoxin below 1 EU/μg as measured by LAL.
- Bioactivity validated in cell-based proliferation assays with low ng/mL ED50.
- Reconstitute at ≥100 μg/mL; add carrier protein for long-term storage.
- Store frozen; stable at -20°C for long-term, and 4°C short-term after reconstitution.
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Eurofins Discoverx TGR5 Receptor Agonist, 5 mg. (92-1196)
TGR5 Receptor Agonist is a synthetic cell-permeable small molecule agonist for the G protein-coupled bile acid receptor TGR5 (pEC50=6.8-7.5 nM). Improves glucagon like peptide-1 (GLP-1) secretion from intestinal cells, and mediates energy balance, inflammation, and digestion. Provided as 5mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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Selleck Chemical LLC 12-Crown-4 E4834-1G
12-crown-4(EOCT Ethylene oxide cyclic tetramer) is an effective phase-transfer catalyst and complexing agent for lithium facilitating the dissolution of lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) without requiring acetonitrile It selectively binds to lithium ions and forms stable complexes significantly improving electrolyte conductivity in lithium batteries and positively influencing ion mobility and overall battery performance
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TARGETMOL CHEMICALS INC BASIMGLURANT 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Basimglurant (CTEP Derivative) is a potent selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM). purity: 99%
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TARGETMOL CHEMICALS INC GV-150013X 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GV-150013X ((S)-1-(1-(adamantan-1-ylmethyl)-24-dioxo-5-phenyl-2345-tetrahydro-1H-benzo[b][14]diazepin-3-yl)-3-phenylurea) is a potent CCKB antiagonist pKi= 9.02. purity: 100%
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Selleck Chemical LLC ML218 E8077-1MG
ML218 is a potent selective and orally active T-type Ca2 channels (Cav3 1 Cav3 2 Cav3 3) inhibitor with IC50s of 310 nM and 270 nM for Cav3 2 and Cav3 3 respectively ML218 inhibits the burst activity in subthalamic nucleus (STN) neurons ML218 has no significant inhibition of L- or N-type calcium channels KATP or hERG potassium channels ML218 can penetrate the blood-brain barrier
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Medchemexpress LLC Methyl (E)-cinnamate | 1754-62-7 | 97.6% | 162.19 g/mol | C10H10O2 | 500 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Methyl (E)-cinnamate is a naturally occurring phytochemical and flavor compound supplied for research and analytical use. It is reported to have anti-inflammatory properties and is used in flavoring and commodity applications. Key identifiers include CAS number 1754-62-7, molecular formula C10H10O2, molecular weight 162.19 g/mol, and typical purity 97.6%.
- Natural flavor compound with reported anti-inflammatory properties.
- Available in 100 g, 500 g, and 1 kg pack sizes.
- Typical purity 97.6%.
- Molecular weight 162.19 g/mol, formula C10H10O2.
- Intended for research and analytical use.
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Cayman Chemical Odanacatib, Purity: ≥98%, CAS: 603139-19-1, 10 mg
A potent, selective, and neutral inhibitor of cathepsin K (IC50s = 0.2 and 1 nM for human and rabbit enzymes, respectively)
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Cayman Chemical AMG 517, Purity: ≥98%, CAS: 659730-32-2, 50 mg
A TRPV1 antagonist (IC50 = 0.9 nM); inhibits mechanical and thermal allodynia in a rat model of burn injury at 165 µg, intrathecally; reverses increases in the level of CGRP and increases expression of GFAP and GAP-43 in the dorsal horn of the spinal cord, as well as enhances axonal regeneration in a rat model of sciatic nerve transection injury
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Cayman Chemical Chlorin e6, Purity: ≥90%, CAS: 19660-77-6, 500 mg
A photosensitizer; active against S. aureus, P. aeruginosa, E. coli, and S. typhimurium when used at 20 µM in combination with PDT; induces tumor regression when combined with PDT in several sarcoma rat xenograft models at 5 and 10 mg/kg
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Cayman Chemical Histamine, Purity: ≥95%, CAS: 51-45-6, 5 g
A biogenic amine; activates histamine H1-4 receptors to regulate allergic and inflammatory responses, gastric acid secretion, arousal, cognition, and immune cell chemotaxis
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Cayman Chemical IbrutInIb-d5 500ug
An internal standard for the quantification of ibrutinib by GC- or LC-MS
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