Bioactive Small Molecules
Medchemexpress LLC Ladarixin sodium | 865625-56-5 | 99.8% | 397.32 | 1 ML
Ladarixin sodium is an orally active, allosteric non-competitive, and dual CXCR1 and CXCR2 antagonist. It can be used for the research of COPD and asthma.
- Orally active
- Allosteric non-competitive antagonist
- Dual CXCR1 and CXCR2 antagonist
- Inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8
- Reduces allergic airway inflammation in single OVA exposure models
- Reduces allergic airway inflammation, remodeling, and bronchial hyperreactivity in chronic OVA exposure models
- Reduces pulmonary inflammation and fibrosis induced by bleomycin in mice
- Protects mice from cigarette smoke-induced exacerbation of influenza-A infection
- Effective in decreasing CXCL8-induced polymorphonuclear leukocyte infiltration in several animal models
Medchemexpress LLC 5'-O-DMT-N6-ibu-dA | 190834-10-7 | 98.0% | 623.70 | 1 ML
5'-O-DMT-N6-ibu-dA is a nucleoside antimetabolite/analog used in the synthesis of oligodeoxyribonucleotides. It targets DNA/RNA Synthesis and the Cell Cycle/DNA Damage pathway.
- Can be used in the synthesis of oligodeoxyribonucleotides
- Store at 4°C, sealed, away from moisture and light
- When in solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month, sealed, away from moisture and light
Cayman Chemical Ribavirin 5'-monophosphate (lithium salt), Purity: ≥90%, CAS: 66983-94-6, 5 mg
Competitively inhibits IMPDH in vitro (Ki = 270 nM); a metabolite of the prodrug ribavirin; broad-spectrum antiviral activity, particularly against influenza and HIV
Medchemexpress LLC Glycerophospho-N-palmitoyl ethanolamine | 100575-09-5 | MFCD11977724 | 99.0% | 453.55 | C21H44NO7P | 5 MG
Glycerophospho-N-palmitoyl ethanolamine is an endogenous glycerophospho lipid supplied as a white to off-white solid for research use. It is intended for use as a biochemical reagent or reference standard in studies of lipid metabolism and signaling and is supplied with supporting documentation including a product data sheet and safety data sheet.
- Endogenous glycerophospho lipid suitable for research use.
- Appearance: white to off-white solid.
- Purity: 99.0%.
- Chemical formula: C21H44NO7P; molecular weight: 453.55 g·mol⁻¹.
- Storage: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months).
- Provided with product data sheet and safety data sheet.
Medchemexpress LLC Colchicoside | 477-29-2 | MFCD01736974 | 99.4% | 547.55 g/mol | C27H33NO11 | 5 MG
Colchicoside (CAS 477-29-2) is a tropolone alkaloid research compound reported to have anti-leishmanial activity. It is supplied as a solid reference material with defined molecular and purity characteristics for laboratory and analytical use.
- High purity solid suitable for research and analytical applications.
- Molecular formula C27H33NO11 and molecular weight 547.55 g/mol.
- Available in small milligram pack sizes for assay and reference use.
- Provided with product and safety documentation for laboratory handling.
- Used as a biochemical standard and research reagent in parasitology studies.
Cayman Chemical Flumequine, Purity: ≥98%, CAS: 42835-25-6, 10 g
A fluoroquinolone antibiotic; active against S. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, and K. pneumoniae (MICs = 1-100 µg/ml); active against field isolates of B. hyodysenteriae (MICs = 6.25-200 µg/ml); increases survival in rat models of P. vulgaris-induced urinary tract infection and P. mirabilis-induced prostatitis at 50 mg/kg
Cayman Chemical 3',4'-tetramethylene-α-Pyrrolidinovalerophenone (hydrochloride), Purity: ≥98%, CAS: 2748590-73-8, 5 mg
A cathinone whose physiological and toxicological properties have not been investigated
TARGETMOL CHEMICALS INC BMS-309403 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BMS-309403 is an effective selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. purity: 98%
Medchemexpress LLC Histone H3 Human H 5ug
Histone H3 proteins are critical in nucleosomes which compact DNA into chromatin and regulate DNA accessibility Histone H3 Protein Human (His) is the recombinant human-derived Histone H3 protein expressed by E coli with N-His labeled tag
Medchemexpress LLC SULT1A1 Human His 250ug
SULT1A1 Protein, Human (His) is a recombinant, full-length human sulfotransferase produced in Escherichia coli with an N-terminal 6xHis affinity tag. Supplied as a stabilized, 0.2 μm filtered solution (250 μg), it is designed for biochemical and enzymatic assays and is characterized by high purity and measured enzymatic activity.
- Full-length human SULT1A1 expressed in E. coli.
- N-terminal 6xHis tag for affinity purification.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Specific activity 56.4 pmol/min/μg (PAPS/1-naphthol assay).
- Stabilized formulation with trehalose, glycerol, and Tween 80 for storage.
- Store at -80°C; avoid repeated freeze-thaw cycles.
Medchemexpress LLC Fmoc-2-Nal-OH | 112883-43-9 | 99.6% | 437.49 | 10 G
Fmoc-2-Nal-OH is an alanine derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements that influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress-related tasks, and prevent exercise-induced muscle damage, making them recognized as beneficial ergogenic dietary substances.
- Used as ergogenic supplements.
- Influences secretion of anabolic hormones.
- Supplies fuel during exercise.
- Supports mental performance during stress-related tasks.
- Prevents exercise-induced muscle damage.
Cayman Chemical Arteether, Purity: ≥95%, CAS: 75887-54-6, 25 mg
An antimalarial compound and derivative of artemisinin; inhibits P. falciparum (IC50 = 1.27 nM in vitro); effective against various strains of P. berghei in mice (ED90 = 0.5-8.2 nM)
Cayman Chemical Cyclopenin, Purity: ≥98%, CAS: 20007-87-8, 5 mg
An AChE inhibitor (IC50 = 2.04 μM for human recombinant AChE); exhibits greater than 2,000-fold selectivity over equine butyrylcholinesterase (IC50 = >4,080 μM)
Cayman Chemical 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone, Purity: ≥95%, CAS: 21618-92-8, 5 mg
An active metabolite of various polyphenols; an inhibitor of MMP-1 and MMP-2 collagen degradation activity (IC50s = 108 and 106 nM, respectively), MMP-1 and MMP-9 gelatin degradation activity (IC50s = 45.2 and 17.7 nM, respectively), and MMP-2 and MMP-9 elastin degradation activity (IC50s = 61.8 and 89 nM, respectively); scavenges free radicals in a TEAC assay
Medchemexpress LLC Phospho-CD18 (Ser745) Antibody (YA220) | 10 UL
The Phospho-CD18 (Ser745) Antibody (YA220) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically designed to target Phospho-CD18 (Ser745). This antibody is suitable for use in research applications such as Western Blot (WB) and Immunoprecipitation (IP), and has been validated for reactivity across human, mouse, and rat species.
- Rabbit-derived monoclonal antibody
- Targets phospho-CD18 (Ser745)
- Non-conjugated IgG type
- Predicted and observed molecular weight is 85 kDa
- Purity is affinity purified
- Reactive in human, mouse, and rat samples
- Applications include Western Blot and Immunoprecipitation
- Supplied in PBS, pH 7.4
- Storage at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipped with blue ice