Bioactive Small Molecules
Medchemexpress LLC Ac2-26 TFA | 151988-33-9 | MFCD00792708 | 98.9% | 3203.45 (free base) | 10 MG
Ac2-26 TFA | 151988-33-9 | MFCD00792708 | 98.9% | 3203.45 (free base) | 10 MG
Medchemexpress LLC Proteasome 20S LMP7 Antibody (YA684) | 10 UL
Proteasome 20S LMP7 Antibody (YA684) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting Proteasome 20S LMP7. This antibody exhibits reactivity with human and rat samples and is utilized in cell biology research.
- Mouse-derived and non-conjugated IgG1 monoclonal antibody
- Targets Proteasome 20S LMP7
- Reactivity with human and rat samples
- Predicted and observed band size of 30 kDa
- Affinity purified
- Applications include Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F), and Immunocytochemistry/Immunofluorescence (ICC/IF)
- Stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Essential for processing class I MHC peptides
Medchemexpress LLC HHS-0701 | 2851993-91-2 | 98.9% | 396.46 | 50 MG
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand and a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. It works by blocking PTGR2 metabolism of the lipid substrate 15-Keto-PGE2.
- Potent PTGR2 inhibitor
- Blocks PTGR2 metabolism of 15-Keto-PGE2
- Shows concentration-dependent blockade of probe labeling in recombinant PTGR2 overexpressing HEK293T cells
Selleck Chemical LLC Anetumab-MMAE-D4006-1MG-5
Anetumab-MMAE is an antibody-drug conjugate (ADC) composed of a human anti-mesothelin (MSLN) antibody and the anti-mitotic cytotoxic agent monomethyl auristatin (MMAE)
Medchemexpress LLC PF-06305591 50mg | 1449473-97-5 | 50 MG
PF-06305591 is a potent, highly selective blocker of the NaV1.8 voltage-gated sodium channel (IC50 = 15 nM). It is supplied as a high-purity solid suitable for preclinical in vitro pharmacology and ADME studies, with recommended cold storage to preserve stability.
- Potent NaV1.8 blockade (IC50 = 15 nM)
- High purity suitable for in vitro research
- Solid powder form with recommended cold storage
- Available in small-scale quantities for preclinical testing
- Also available as a DMSO solution option for cell-based assays
Medchemexpress LLC LPA2 antagonist 2 | 36840-10-5 | 95.0% | 380.35 | 1 ML
LPA2 antagonist 2 (H2L 5226501) is a selective antagonist of LPA2 with an IC50 of 28.3 nM and a Ki of 21.1 nM, demonstrating more than 480-fold selectivity over LPA3. Lysophosphatidic acid (LPA) is a phospholipid mediator involved in various biological effects, including cell proliferation, survival, motility, and differentiation. This compound inhibits LPA1 with an Imax of 59.0% at 30 μM.
- Inhibits LPA1 with an Imax of 59.0% at 30 μM.
- LPA has been linked to the regulation of cancer cell invasion, metastasis, and resistance to chemotherapeutics and radiation.
- Appears as a solid.
- Color is light yellow to yellow.
- Soluble in DMSO: 83.33 mg/mL (219.09 mM); requires sonication.
- Powder storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 2 years, -20°C for 1 year.
Cayman Chemical C15 GalactosylcRamIDd18 1 5mg
A glycosphingolipid; contains a galactose moiety attached to a ceramide acylated with pentadecanoic acid
Cayman Chemical ANTIBODY NAB 2 10mg
An inhibitor of α-synuclein-induced toxicity; prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells; prevents formation of α-synuclein foci in wild-type yeast cells
Cayman Chemical ANTIBODY GSK690693 10mg
An ATP-competitive, pan-Akt kinase inhibitor (IC50s = 2, 13, and 9 nM for Akt1, 2, and 3, respectively) that inhibits proliferation and induces apoptosis in various human tumor cells in vitro and in xenografts in immunocompromised mice
Cayman Chemical ANTIBODY UrIdIn 25g
A pyrimidine nucleoside; forms complementary base pairs with adenosine in RNA; replaced with thymidine in DNA
Medchemexpress LLC Levocetirizine dihydrochloride | 130018-87-0 | 99.8% | 461.81 | 500 MG
Levocetirizine dihydrochloride is a third-generation peripheral H1-receptor antagonist. It is an antihistaminic agent, specifically the R-enantiomer of Cetirizine. This compound demonstrates a higher affinity for the histamine H1-receptor compared to (S)-Cetirizine, making it effective in treating allergic rhinitis and chronic idiopathic urticaria. It is intended for research use only.
- Third-generation peripheral H1-receptor antagonist
- R-enantiomer of Cetirizine
- Higher affinity for the histamine H1-receptor compared to (S)-Cetirizine
- Effective in treating allergic rhinitis and chronic idiopathic urticaria
- Intended for research use only
Medchemexpress LLC Acetyl CoA Carboxylase 1 (ACC1) Antibody (YA646) | 266 kDa | 10 UL
Acetyl CoA Carboxylase 1 (ACC1) Antibody (YA646) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Acetyl CoA Carboxylase 1 (ACC1). This antibody is suitable for research use only and ships with blue ice, ensuring stability. It is formulated in TBS with BSA and Glycerol, including sodium azide as a preservative, and is stable for 1 year when stored at -20°C.
- Targets Acetyl CoA Carboxylase 1 (ACC1)
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated and unmodified
- Reactive with human and mouse samples
- Applications include Western Blot (WB) and Immunohistochemistry-Paraffin (IHC-P)
- Predicted molecular weight of 266 kDa
- Protein A affinity purified
- Ships with blue ice for stability
Cayman Chemical ANTIBODY GSK2656157 5mg
A selective inhibitor of PERK (IC50 = 0.9 nM); blocks both stress-induced PERK autophosphorylation and eIF2α substrate phosphorylation and decreases levels of ATF4 and CHOP in multiple cell lines
Cayman Chemical Boldenon Undecylenate 5mg
An analytical reference standard categorized as an anabolic androgenic steroid; has been used to enhance physical performance in racehorses and athletes; intended for research and forensic applications
Apexbio Technology LLC Alcaftadine 147084-10-4 10mM (in 1mL DMSO)
Alcaftadine (CAS 147084-10-4) is a small-molecule histamine H1 receptor antagonist that inhibits the actions of histamine thereby mitigating inflammatory responses By blocking H1 receptor activation on conjunctival cells it prevents downstream signaling events associated with allergic symptoms such as pruritus Alcaftadine is utilized as a pharmacological tool to study histamine-mediated pathways and allergic cascade mechanisms with particular relevance to ocular models of allergic conjunctivitis Its approval for clinical use underscores its selectivity for the H1 receptor and its utility in delineating histamine-driven immunological processes