Isotopically Labeled Compounds
Medchemexpress LLC Reserpine-d9 | 84759-11-5 | 617.73 | 5 MG
Reserpine-d9 is the deuterium labeled Reserpine. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Stable heavy isotopes have been incorporated into this compound for quantitation during drug development. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Has the potential to affect the pharmacokinetic and metabolic profiles of drugs due to deuteration.
Medchemexpress LLC Ethosuximide-d3 | 1189703-33-0 | ≥99.0% | 1 MG
Ethosuximide-d3 is the deuterium labeled Ethosuximide. It is a widely prescribed anti-epileptic agent that improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled ethosuximide.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Improves phenotypes of multiple neurodegenerative disease models.
- Blocks low voltage activated T-type calcium channel.
- Deuterium substitution can affect pharmacokinetic and metabolic profiles of drugs.
eMolecules 1020719-86-1 | Medchem Express | Sulfamethoxazole-d4 | 1mg | 673359082 | HY-B0322S | MFCD03425632 | 257.3 | C10H11N3O3S
Medchem Express | Letrazuril | 5mg | 446259027 | HY-106859 | 103337-74-2 | MFCD00867212 | 391.180 | C17H9Cl2FN4O2
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Cayman Chemical Ketotifen-13C-d3, Purity: ≥99% deuterated forms (d1-d3), CAS: 2748522-40-7, 1 mg
An internal standard for the quantification of ketotifen by GC- or LC-MS
Medchemexpress LLC Ponesimod-d7 | 00-00-0 | 96.5% | 468.02 g/mol | C23H18D7ClN2O4S | 50 MG
Ponesimod-d7 is a deuterium-labeled isotopologue of ponesimod supplied as a 50 mg reference standard for analytical and research use. It is intended for use as a stable-isotope internal standard in mass spectrometry, tracer experiments, and pharmacokinetic studies; store and handle according to supplier recommendations.
- Deuterium-labeled isotopologue for use as a stable-isotope reference.
- Suitable as an internal standard for LC-MS/MS quantitation.
- High isotopic enrichment to support accurate tracer studies.
- Supplied as a 50 mg powder with recommended storage at -20°C.
- Useful for pharmacokinetic and metabolite identification studies.
Medchemexpress LLC Sacubitril-d4 hemicalcium salt | 1369773-39-6 | C24H25D4NO50.5Ca | 1 MG
Sacubitril-d4 hemicalcium salt is the deuterium labeled Sacubitril hemicalcium salt. Sacubitril hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process.
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC N-valerylglycine-d2 | 3008541-76-9 | 95.0% | 161.20 g/mol | C7H11D2NO3 | 5 MG
N-Valerylglycine-d2 is the deuterium-labeled (d2) analogue of N-valerylglycine provided for laboratory research use. It is designed as a stable-isotope tracer or internal standard to support accurate quantitation in analytical workflows such as NMR, GC-MS, and LC-MS. Supplied as a solid with defined purity and identified by its CAS number for unambiguous reference.
- Deuterium-labeled analogue suitable as tracer or internal standard.
- Supports quantitative analysis by NMR, GC-MS, and LC-MS.
- Molecular formula C7H11D2NO3 and molecular weight 161.20 g/mol.
- CAS number 3008541-76-9 for unambiguous identification.
- Available in laboratory pack sizes, including 5 MG.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Roflumilast-d4 | 1398065-69-4 | C17H10D4Cl2F2N2O3 | 1 MG
Roflumilast-d4 is a deuterium-labeled selective PDE4 inhibitor, primarily used for research. It can be utilized as a tracer or an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS. Incorporating stable heavy isotopes into drug molecules, such as deuterium, aids in quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Acesulfame-d4 potassium | 1623054-53-4 | 1 MG
Acesulfame-d4 potassium is the deuterium labeled Acesulfame (potassium) (HY-D0195). Acesulfame potassium is an artificial sweetener that affects cognitive functions, potentially by altering neuro-metabolic functions in mice.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Aldosterone-2,2,4,6,6,21,21-d7 >=98 atom % D (based on d7), >=98% (CP) | 1261254-31-2 | 2MG
Aldosterone-2,2,4,6,6,21,21-d7 >=98 atom % D (based on d7), >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 367.49 | 1261254-31-2 | 2MG
Cayman Chemical AxItInIb-13C-d3 500ug
An internal standard for the quantification of axitinib by GC- or LC-MS
Medchemexpress LLC Menadione-d3 (Vitamin K3-d3) | 5172-16-7 | 99.1% | 5 MG
Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo. This compound is for research use only and not sold to patients.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS