Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

Search Within Results

5,401 – 5,415 of 5,862 results

5,401

Medchemexpress LLC G4RGDSP, integrin-binding peptide | 774577-43-4 | 99.61% | 758.74 | 100 MG

G4RGDSP, integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. It is coupled to alginate to increase the viability of cells in the scaffold and can be used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology.

Targets integrin receptors
Increases viability of cells in scaffold
Suitable for chondrocyte delivery studies
Used in 3D printing technology research
Increases expression of aggregin, collagen type II, and sox9 genes in HAC cells

Pricing & Availability

5,402

Medchemexpress LLC HY-B2156 100mg Medchemexpress, Menaquinone-4 CAS:863-61-6 Purity:>98%

Medchemexpress, HY-B2156 100mg Menaquinone-4 CAS:863-61-6 Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Pricing & Availability

5,403

Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 ML

BI-2865 is a non-covalent pan-KRAS Inhibitor. It binds to wild-type and various mutant KRAS forms, including G12C, G12D, G12V, and G13D, inhibiting the proliferation of mutant KRAS expressing BaF3 cells. Characterized by a prolinol substituent and a pyrimidine linker, it forms specific interactions within the KRAS binding site. This product is for research use only.

Binds to wild-type and various mutant KRAS forms
Inhibits proliferation of mutant KRAS expressing BaF3 cells
Features a prolinol substituent and a pyrimidine linker
Demonstrates direct ionic interaction with E62
Forms a water-mediated hydrogen bond network with R68 and Q61

Pricing & Availability

5,404

Medchemexpress LLC BI-2493 | 2937344-16-4 | C24H27N7OS | 50 MG

BI-2493 is a structural analogue of BI-2865 and a highly selective and orally active pan-KRAS inhibitor. It is designed to attenuate tumor growth and is primarily used for cancer diseases research.

Highly selective and orally active pan-KRAS inhibitor
Attenuates tumor growth
Used for cancer diseases research
Inhibits proliferation of KRAS mutant cancer cell lines in a concentration-dependent manner
Exhibits tumor-suppressive activity in xenograft mouse models

Pricing & Availability

5,405

Medchemexpress LLC Talibegron hydrochloride (ZD2079 hydrochloride) | 178600-17-4 | C18H22ClNO4 | 1 MG

Talibegron hydrochloride (ZD2079 hydrochloride) is a potent β3-adrenoceptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. It has a potent vasorelaxant effect.

Potent β3-adrenoceptor agonist.
Has potent vasorelaxant effect.
Produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries.
Causes full relaxation with 1 mM.

Pricing & Availability

5,406

Medchemexpress LLC Alprenolol hydrochloride | 13707-88-5 | 99.8% | 500 MG

Alprenolol hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. It is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent.

Orally active non-selective β-adrenoceptor antagonist.
Antagonizes 5-HT1A and 5-HT1B receptors.
Used as an anti-hypertensive, anti-anginal, and anti-arrhythmic agent.
High purity of 99.76%.
Soluble in DMSO (100 mg/mL) and water (50 mg/mL).
Formulations available for oral and intraperitoneal injection.

Pricing & Availability

5,407

Medchemexpress LLC Givinostat hydrochloride | 199657-29-9 | MFCD28502062 | 98.1% | 457.95 | 100 MG

Givinostat hydrochloride is a Histone Deacetylase (HDAC) inhibitor that can penetrate the blood-brain barrier (BBB). It is known to inhibit HDAC1 and HDAC3, and has shown efficacy in suppressing inflammatory responses and inhibiting cell proliferation in various studies.

Inhibits HDAC1 (IC50: 198 nM) and HDAC3 (IC50: 157 nM)
Penetrates the blood-brain barrier (BBB)
Suppresses LPS-induced IL-1β production
Decreases IL-6 secretion in PBMCs
Inhibits JS-1 cell proliferation

Pricing & Availability

5,408

Medchemexpress LLC Irinotecan hydrochloride trihydrate | 136572-09-3 | 99.9% | 677.18 | 100 MG

Irinotecan hydrochloride trihydrate is a topoisomerase I inhibitor with antitumor activity, used to treat colon and rectal cancer. It is for research use only and has been shown to inhibit the growth of various cancer cell lines, such as LoVo and HT-29.

Inhibits topoisomerase I
Demonstrates antitumor activity
Suppresses proliferation of human umbilical vein endothelial cells
Available for research use only

Pricing & Availability

5,409

Medchemexpress LLC Benzenesulfonamide, 4-[(6-amino-4-pyrimidinyl)amino]-, hydrochloride (1:1) | 21886-12-4 | 99.6% | 301.75 | 25 MG

PNU112455A hydrochloride is an ATP-competitive inhibitor of CDK2 and CDK5. It binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively. This product is for research use only and is not sold to patients.

ATP-competitive CDK2 and CDK5 inhibitor.
Binds to the ATP site of CDK2 and CDK5.
Purity: 99.56%.
Available in various sizes and concentrations, including solid and solution forms.
Soluble in DMSO and H2O.
Provided with detailed solubility and storage information for both in vitro and in vivo applications.

Pricing & Availability

5,410

Apexbio Technology LLC Menadione, 10mM (in 1mL DMSO). Cas: 58-27-5 MFCD: MFCD00001681. precursor to vitamin K2

Menadione (vitamin K3), used as a nutritional supplement, is an inhibitor of mitochondrial DNA polymerase γ (pol γ), with an IC 50 value of 6 µM. Pol γ is responsible for all aspects of mitochondrial DNA synthesis, including all replication, recombination of the mitochondrial genome, and repair of mitochondrial DNA damage. Other sizes are available. Please inqury us for quote.

Pricing & Availability

5,411

Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 25 MG

Givinostat hydrochloride monohydrate is a potent HDAC inhibitor, demonstrating IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3. This compound is notable for its ability to penetrate the blood-brain barrier, making it suitable for a range of research applications.

Potent HDAC inhibitor for HDAC1 and HDAC3
Penetrates the blood-brain barrier
Suppresses LPS-induced IL-1β and IL-6 production
Inhibits JS-1 cell proliferation
Reduces serum TNFα and IL-1β levels in vivo

Pricing & Availability

5,412

Medchemexpress LLC Xaliproden hydrochloride | 90494-79-4 | 98.4% | 417.89 | 1 ML

Xaliproden hydrochloride (SR57746A) is a potent, selective, and orally active agonist of the 5-HT1A receptor, showing high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50=3 nM). It is also a selective antagonist of the dopamine D2 receptor, with moderate affinity (IC50=0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects and may have therapeutic potential for the research of neurodegenerative diseases.

Potent, selective, and orally active 5-HT1A receptor agonist
High affinity for 5-HT1A specific binding sites (IC50=3 nM)
Selective antagonist of the dopamine D2 receptor
Moderate affinity for D2 receptor (IC50=0.1-1 μM)
Exhibits anti-depression and anti-anxiety effects
May have therapeutic potential for neurodegenerative disease research

Pricing & Availability

5,413

Medchemexpress LLC 5-pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 50 MG

This product is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma. It can also significantly inhibit AHR in mice and effectively block edema formation while reducing inflammatory infiltrate and skin pathology in drug vehicle-treated animals.

Highly specific and potent antagonist of CRTH2.
Demonstrates low nanomolar potency against human and mouse CRTH2 in transfected cells.
Shows significant inhibition of airway hyperreactivity (AHR) in mice.
Effectively blocks edema formation in animal models.
Reduces inflammatory infiltrate and skin pathology.
Potential for treating poorly controlled asthma.

Pricing & Availability

5,414

Apexbio Technology LLC BI 2536(Synonyms: BI-2536, BI2536, Plk1 inhibitor BI 2536), 50mg, CAS: 755038-02-9.

BI 2536 (CAS number 755038-02-9) is an ATP-competitive inhibitor selectively targeting human polo-like kinase 1 (PLK1) exhibiting an IC50 value of approximately 0 83 nM Comparatively BI 2536 shows substantially less affinity towards other kinases In vitro studies demonstrate that BI 2536 inhibits proliferation of various human tumor cell lines (EC50 values ranging from 2 to 25 nM) and induces G2/M cell cycle arrest accompanied by apoptosis as evidenced in HeLa cervical cancer cells In vivo data from xenograft tumor models indicate that BI 2536 administered intravenously on a weekly or biweekly schedule possesses antitumor efficacy

Pricing & Availability

5,415

Medchemexpress LLC PNU112455A hydrochloride | 21886-12-4 | 99.6% | 301.75 | 1 ML

PNU112455A hydrochloride is an ATP-competitive inhibitor of CDK2 and CDK5. It binds to the ATP site of CDK2 and CDK5 with Km values of 3.6 μM and 3.2 μM, respectively. This product is intended for research use only and is not sold to patients.

ATP-competitive CDK2 and CDK5 inhibitor.
Binds to the ATP site of CDK2 and CDK5.
Km for CDK2: 3.6 μM.
Km for CDK5: 3.2 μM.
Purity: 99.56%.
Appearance: Solid, Light yellow to yellow.
Shipping: Room temperature in continental US.
Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month.

Pricing & Availability

Naphthalenes

Filtered Search Results

Narrow Results

Medchemexpress LLC G4RGDSP, integrin-binding peptide | 774577-43-4 | 99.61% | 758.74 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-B2156 100mg Medchemexpress, Menaquinone-4 CAS:863-61-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-2493 | 2937344-16-4 | C24H27N7OS | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Talibegron hydrochloride (ZD2079 hydrochloride) | 178600-17-4 | C18H22ClNO4 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alprenolol hydrochloride | 13707-88-5 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Givinostat hydrochloride | 199657-29-9 | MFCD28502062 | 98.1% | 457.95 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Irinotecan hydrochloride trihydrate | 136572-09-3 | 99.9% | 677.18 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Benzenesulfonamide, 4-[(6-amino-4-pyrimidinyl)amino]-, hydrochloride (1:1) | 21886-12-4 | 99.6% | 301.75 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Xaliproden hydrochloride | 90494-79-4 | 98.4% | 417.89 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PNU112455A hydrochloride | 21886-12-4 | 99.6% | 301.75 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More